... necrosis factor-alpha (TNF-a) and interleukin-6 (IL-6), resulting in aheightened degree of inflammation [5].Lipid meta bolites and cytokines, including chemokines and growth factors, are the ... recom-binant cytokines was used to establish standard curves and to maximize the sensitivity and dynamic range ofthe assay. Cytokine levels were determined using aLuminex IS 100 (Luminex, Austin, ... environmental factors and countless interactions with infectious agents leads to achronic inflammatory state in older individuals, termedinflammaging, characterized by an increase in proinflam-matory...