Báo cáo khoa học: "CONCURRENT PARSING IN PROGRAMMABLE LOGIC ARRAY PROBLEMS AND PROPOSALS" docx

... conceptual and practical introduction into the principles of wiring or constructing special machines for language processing tasks instead of programming a universal machine. Construction would in ... in principle, could not be solved by programming. It is simply the case that almost all solutions are descriptively inadequate for representing and understanding what goes on in human beings ... The diagram includes the input and output registers, in order to show how easily these are integrated into the PLA design. The inputs stored during [clocksig- nal] ~l in the input register...

Tài liệu Báo cáo khoa học: The role in the substrate speciﬁcity and catalysis of residues forming the substrate aglycone-binding site of a b-glycosidase docx

... be of particular importance in understanding thephysiological role of b-glycosidases and in designinginhibitors. In addition, another important issue in understand-ing the aglycone speciﬁcity ... aglycone-binding site in the stabilizationof ESà and the interdependence between the binding ofaglycone and the positioning of glycone in subsite )1are not known. In this study, the role in the ... was included to facilitate the visualization of the active site. (C) Agly-cone-binding site of SbDhr1, including the substrate dhurrin. (D) Aglycone-binding site of BglB, including the inhibitor...

Tài liệu Báo cáo khoa học: Caveolin-1 inﬂuences P2X7 receptor expression and localization in mouse lung alveolar epithelial cells docx

... P2X7protein. Indeed, suppression of Caveolin-1 protein expression in E10 cells using short hairpin RNAs resulted in a large reduction in P2X7protein expression. Our data demonstrate a potential interaction ... physiologic role of caveolae and Caveolin-1could be to centralize, concentrate and colocalize part-ner proteins, signaling proteins and effectors withinlipid rafts. For some proteins, Caveolin-1 ... Caveolin-1 and P2X7distribution in control and in Caveolin-1 shRNA-transfected E10 cells.Note the loss of colocalization of Caveolin-1 and P2X7 in Cav-1 shRNA treated cells.Caveolin-1 and...

Tài liệu Báo cáo khoa học: Adaptive changes in the expression of nuclear and mitochondrial encoded subunits of cytochrome c oxidase and the catalytic activity during hypoxia pptx

... Chaps and 150 mMNaCl and protease inhibitors [5 lgÆmL)1pepstatinA, 5 lgÆmL)1aprotinin, and 1 mMphenylmethanesulfonylﬂuoride]) and lysed by three cycles of freezing and thawing in liquid ... lgÆmL)1penicillin/streptomycin. The myocyteswere induced to differentiate into myoblasts by replacing themedium at conﬂuence with a fresh medium containing 2%(v/v) fetal bovine serum. These ... not been investigated in detail. In a previous study we demonstrated that administrationof inhibitors of heme biosynthesis (succinyl acetone and cobalt chloride) to mice, resulted in a 50% reduction...

Tài liệu Báo cáo khoa học: "Text Alignment in a Tool for Translating Revised Documents" docx

... away the situation is interpreted as involving two indepen- dent editing operations. The window is set to 4, since the dynamic programming approach is very fast in recovering from local errors. ... to handle insertions and deletions. The algorithm that was developed for aligning paragraphs is a nat- ural choice. It handles insertions and deletions suc- cessfully and it has certain other ... assumption can still be main- rained. Gale and Church hint that their method 449 works well for aligning sentences within paragraphs and that they use different means to find the corre- spondence...

Báo cáo khoa học: Protein transport in organelles: The composition, function and regulation of the Tic complex in chloroplast protein import pptx

... CaM-bindingdomains, and contains at least one conserved potentialCaM-binding motif [46]. Additionally, the binding ofCaM at the C-terminus and the binding of NADPH atthe extreme N-terminus ... domains are degenerate 34-amino acidrepeats forming anti-parallel a-helices known to beinvolved in an array of protein–protein interactions(generally with non-TPR proteins) [41]. Both domainsare ... in two distinct modules. The N-terminus contains the dehydrogenase domain (green) and might mediate membrane binding via a hydrophobic patch on the surface of the protein, whereas the C-terminus...

Báo cáo khoa học: Protein transport in organelles: Protein transport into and across the thylakoid membrane pptx

... ª 2009 FEBSMINIREVIEWProtein transport in organelles: Protein transport into and across the thylakoid membraneCassie Aldridge*, Peter Cain* and Colin RobinsonDepartment of Biological Sciences, ... proteinaceous insertion machinery. Other single-spanning proteins have also been suggested to use thismembrane integration route, including the photosys-tem II subunits, PsbW and PsbX. In describing ... vicinity ofthe twin arginine motif, whereas Hcf106 cross-linksless strongly to residues in the hydrophobic core and the early mature protein [32]. Binding of the precursorcan occur in the absence...

Báo cáo khoa học: Nucleosome positioning in relation to nucleosome spacing and DNA sequence-speciﬁc binding of a protein doc

... have shown in this study thattrans-acting proteins are the dominant determinantsfor nucleosome positioning and spacing. Several exam-ples of nucleosome positioning due to the binding of atranscription ... loa-ded in a 1% agarose gel containing 15 lm chloroquin. Thegel was run at 60 V for 12 h in 1 · TBE buffer containing15 lm (10 lgÆmL)1) chloroquin. Chloroquin was removedbefore staining the ... ª 2007 FEBSNucleosome positioning in relation to nucleosome spacing and DNA sequence-speciﬁc binding of a proteinRama-Haritha Pusarla*, Vinesh Vinayachandran* and Purnima BhargavaCentre for...

Báo cáo khoa học: "Semantic parsing with Structured SVM Ensemble Classiﬁcation Models" docx

... domain of semantic parsing shows ad-vantages in comparison with the originallarge margin methods.1 IntroductionNatural language semantic parsing is an interest-ing problem in NLP (Manning and ... consists of a train-ing and a testing phase. In the training phase, eachindividual SSVM is trained independently by itsown replicated training data set via a bootstrapmethod. In the testing phase, ... learning and averaging phases in which the learning phases areeither a boosting or a bagging model, and the av-eraging phase is based on a switching method onoutputs obtained from all individual...

Báo cáo khóa học: Genetic defects in fatty acid b-oxidation and acyl-CoA dehydrogenases Molecular pathogenesis and genotype–phenotype relationships ppt

... mis-sense sequencevariations, in addition to in uencing protein biogenesis, alsomay affect the splicing efficiency by interfering with bindingsites for splice modulating factors [19]. Although ... alsoreflected in the profile of acyl-carnitines in blood and in patient cells metabolizing long-chain fatty acids [27]. Notsurprisingly, the severe metabolic block results in profoundenergy deficiency and ... enzyme.Investigations of biogenesis and stability In the late 1980s and early 1990s it was realized that theexpression and folding of many cellular proteins, includingmitochondrial proteins,...

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