Báo cáo khoa học: Presence of membrane ecdysone receptor in the anterior silk gland of the silkworm Bombyx mori pdf
Báo cáo khoa học: A role for serglycin proteoglycan in granular retention and processing of mast cell secretory granule components ppt
... following exposure to calcium iono-phore, indicating that they were correctly targeted into secretory granuleseven in the absence of serglycin. In the absence of serglycin, the fates of the serglycin-dependent ... on serglycin. Together,these findings indicate that the reduced amounts of neutral proteases in the absence of serglycin is not caused by missorting into the constitutive path-way of secretion, ... explan-ation for these findings would be that the absence of SG causes missorting of mMCP-6 and pro-CPA into the constitutive rather than into the regulated pathway of secretion. If indeed this were the case,...
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Báo cáo khoa học: Calcium, mitochondria and oxidative stress in neuronal pathology Novel aspects of an enduring theme pdf
... increase in the amount of ROS [21]; (b) loss of cytochrome c impairs the flow of electrons in the respiratory chain inducing over-reduction of the complexes, favouring the generation of ROS [16,17,22]; ... con-tribute to the latent [Ca2+]crise in the context of glutamate-induceddelayed calcium deregulation; (b) the likelihood of the involvement of the channels in the phenomenon of ‘Ca2+paradox’ ... upon which the cell looses the ability to buffer the incoming calciumresulting in an abrupt, sustained and irreversibleincrease in [Ca2+]c, probably coincides with the clea-vage of the exchanger...
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Báo cáo khoa học: A di-leucine sorting signal in ZIP1 (SLC39A1) mediates endocytosis of the protein doc
... detec-ted in the perinuclear region of the CHO cells with apunctate distribution in the cytoplasm of the cell(Fig. 2A). The perinuclear staining of the wt ZIP1-Mycprotein was strikingly coincident ... contrast, in the presence of chloroquine, the total ZIP1-Myc accumula-tion in the CHO cells expressing the wt ZIP1-Myc pro-tein was increased to the level that was detected in the cells expressing the ... the surface of these cells were internalized after 1 h of incubation(Fig. 5H), indicating that the endocytic machinery in these mutant ZIP1-Myc expressing cells was intact.Taken together, these...
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Báo cáo khoa học: Adeno-associated virus gene transfer in Morquio A disease – effect of promoters and sulfatase-modifying factor 1 pot
... and production of the target protein[43,44]. The results presented in this work agree withprevious reports showing that the inclusion of a syn-thetic intron and the use of the bovine growth hor-mone ... 0.226). The differencebetween the increases in GALNS enzyme activities andmRNA levels could be explained by the presence of additional sequences within the cassette (Fig. 1). The synthetic intron ... substantial increase in GALNS activity in trans-duced cells and their media, indicating the advantage of coexpression of SUMF1 and GALNS. The effect of SUMF1 coexpression on the sulfatase activity is in u-enced...
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Báo cáo khoa học: Presence of membrane ecdysone receptor in the anterior silk gland of the silkworm Bombyx mori pdf
... Presence of membrane ecdysone receptor in the anterior silk gland of the silkworm Bombyx mori Mohamed Elmogy, Masafumi Iwami and Sho SakuraiDivision of Life Sciences, Graduate School of Natural ... determinedusing 25 nM[3H]PonA and increasing amounts of proteins in individual incubations. The percentage of specific b indingincreased in a protein concentration-dependent mannerwithin the range of ... only in the pelletafter the first centrifugation step. On increasing the concentration of Triton X-114, the binding activity wasrecovered predominantly in the detergent-rich phase. The binding in...
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Tài liệu Báo cáo khoa học: Specific membrane binding of the carboxypeptidase Y inhibitor IC, a phosphatidylethanolamine-binding protein family member doc
... little information is available regard-ing the phospholipid and membrane binding of the other members of the PEBP family. Consequently, the binding characteristics of PEBP proteins, includingthose ... the CPY-binding sites participates in regulation of the specific binding of ICto the anionicphospholipid membranes (Fig. 4A). The participation of the N-terminal region of bovine PEBP in its ... CPY-binding sites of IC in its membrane bindingAs IC–CPY has no affinity for phospholipid membranes,to obtain additional information on the involvement of the CPY-binding sites of IC in its phospholipid...
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Tài liệu Báo cáo khoa học: Structure and membrane interaction of the internal fusion peptide of avian sarcoma leukosis virus pdf
... that the helicalstructure was enhanced in association with the modelmembranes, p articularly in the N -terminal portion of the peptide. According to the infrared study, the peptide insertedinto ... bilayer, including in particular the structural in uence of proline. Consistentwith other c lass I viral fus ion proteins, the IFP o f ASLVinserts into the membrane primarily as a h elix in contrastto ... contrastto the I FP of class II fusion protein which uses a Ôcd loopÕto insert into the target membrane in the fusion process[10,11]. In the following, a variety of physical properties of the putative...
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Báo cáo khoa học: Solution and membrane-bound chaperone activity of the diphtheria toxin translocation domain towards the catalytic domain" doc
... equilib-rium of the C domain in favor of the MG state. The T domain favors the interaction of the C domainwith the membrane, because it brings the C domain in its MG state into the vicinity of the bilayer, ... transloca-tion, the C domain and only the 63 N-terminal aminoacids of the T domain are present on the trans side of the membrane [24,25]. The remaining 124 amino acids of the T domain are left in the membrane. ... toxin lacking the receptor- bindingdomain), each of these steps. The behavior of the T domain is marginallymodified by the presence or absence of the C domain, whereas that of the C domain is greatly...
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Báo cáo khoa học: Catalytically active membrane-distal phosphatase domain of receptor protein-tyrosine phosphatase a is required for Src activation doc
... submitted),suggesting the presence of other Src-binding sites in RPTPa. Taken together, phosphorylation of Tyr789 isnot the only determinant in Src binding. Instead, weprovide evidence that other features of ... domains of RPTPs are involved in protein–protein interactions[16–18,20,28]. We investigated whether the introduc-tion of inactivating mutations in RPTPa-D2 (R554Hand C723S) affected the interaction ... structures of LAR andCD45, another role of the D2 domain was proposed:stabilization of the D1 domain [7,22]. These interactionssuggest that the D2 domains function as regulators of the activity of the...
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Báo cáo khoa học: Presence of melanocortin (MC4) receptor in spiny dogfish suggests an ancient vertebrate origin of central melanocortin system pot
... been found in brain tissue [8,41]. The DreMC4 receptor was also found in the brain but rather surprisingly also in the eye, gastro-intestinal tract and ovaries. In chicken, the MC4 receptor isexpressed ... RT-PCR. The results of the RT-PCR are shown in Fig. 5. The SacMC4 receptor was expressed in five brain regions (Fig. 6) but not in any of the peripheral tissues. There were strong signals in the brain ... withfeeding [37,38]. In the brainstem, the SacMC4 receptor could be involved in visceral afferent signals from the gut via the nucleus of the solitary tract (NTS). The NTS could besending signals...
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Từ khóa: Nghiên cứu sự hình thành lớp bảo vệ và khả năng chống ăn mòn của thép bền thời tiết trong điều kiện khí hậu nhiệt đới việt namNghiên cứu tổ hợp chất chỉ điểm sinh học vWF, VCAM 1, MCP 1, d dimer trong chẩn đoán và tiên lượng nhồi máu não cấpBiện pháp quản lý hoạt động dạy hát xoan trong trường trung học cơ sở huyện lâm thao, phú thọGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANQuản lý hoạt động học tập của học sinh theo hướng phát triển kỹ năng học tập hợp tác tại các trường phổ thông dân tộc bán trú huyện ba chẽ, tỉnh quảng ninhPhát triển mạng lưới kinh doanh nước sạch tại công ty TNHH một thành viên kinh doanh nước sạch quảng ninhPhát hiện xâm nhập dựa trên thuật toán k meansNghiên cứu về mô hình thống kê học sâu và ứng dụng trong nhận dạng chữ viết tay hạn chếNghiên cứu tổng hợp các oxit hỗn hợp kích thƣớc nanomet ce 0 75 zr0 25o2 , ce 0 5 zr0 5o2 và khảo sát hoạt tính quang xúc tác của chúngĐịnh tội danh từ thực tiễn huyện Cần Giuộc, tỉnh Long An (Luận văn thạc sĩ)Tìm hiểu công cụ đánh giá hệ thống đảm bảo an toàn hệ thống thông tinThơ nôm tứ tuyệt trào phúng hồ xuân hươngThiết kế và chế tạo mô hình biến tần (inverter) cho máy điều hòa không khíSở hữu ruộng đất và kinh tế nông nghiệp châu ôn (lạng sơn) nửa đầu thế kỷ XIXBT Tieng anh 6 UNIT 2Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtMÔN TRUYỀN THÔNG MARKETING TÍCH HỢP