Báo cáo khoa học: Apolipoprotein E-derived antimicrobial peptide analogues with altered membrane affinity and increased potency and breadth of activity pdf

Tài liệu Báo cáo khoa học: Mouse recombinant protein C variants with enhanced membrane affinity and hyper-anticoagulant activity in mouse plasma pptx

Tài liệu Báo cáo khoa học: Mouse recombinant protein C variants with enhanced membrane affinity and hyper-anticoagulant activity in mouse plasma pptx

... important membrane phospholipids in promoting efficient binding, complex assembly and enzyme catalysis in vivo. Membrane affinity of a Gla protein often correlates with its membrane localized activity. ... into the Gla protein membrane interaction and identify new reagents with varying degrees of anticoagulant potency that may be of use for testing in murine models of...
Ngày tải lên : 18/02/2014, 06:20
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Báo cáo khoa học: Starch-binding domains in the CBM45 family – low-affinity domains from glucan, water dikinase and a-amylase involved in plastidial starch metabolism pptx

Báo cáo khoa học: Starch-binding domains in the CBM45 family – low-affinity domains from glucan, water dikinase and a-amylase involved in plastidial starch metabolism pptx

... Department of Plant Biology and Biotechnology, Faculty of Life Sciences, University of Copenhagen, Frederiksberg, Denmark 3 Department of Biology, ETH Zu ¨ rich, Switzerland 4 Department of Biology, ... evolution of low -affinity domains is a recurring and functionally important theme in plastid- ial starch metabolism. Results and Discussion Identification and bioinformatic...
Ngày tải lên : 06/03/2014, 00:21
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Báo cáo khoa học: nNOS inhibition, antimicrobial and anticancer activity of the amphibian skin peptide, citropin 1.1 and synthetic modifications pot

Báo cáo khoa học: nNOS inhibition, antimicrobial and anticancer activity of the amphibian skin peptide, citropin 1.1 and synthetic modifications pot

... the average IC 50 concentration of the peptide against that group of cancers and the number of tumours, out of 60 tested, that were affected by the particular peptide. For details of how the IC 50 value ... active peptides, suggests that the anticancer activity is also due to penetration and disruption of the membranes of the cancer cells. The selectivity of these pep...
Ngày tải lên : 17/03/2014, 09:20
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Tài liệu Báo cáo khoa học: The Alzheimer b-peptide shows temperature-dependent transitions between left-handed 31-helix, b-strand and random coil secondary structures doc

Tài liệu Báo cáo khoa học: The Alzheimer b-peptide shows temperature-dependent transitions between left-handed 31-helix, b-strand and random coil secondary structures doc

... radius dependence on number of residues for a polypeptide chain in ideal random coil, b-strand and PII-helix conformations. Measurements of translational diffu- sion for the Ab(12–28) and Ab(1–9) peptides were performed ... controller. A quartz cell with 2 mm optical path was used. The spectral range was 190– 250 nm with a resolution of 0.2 nm and a bandwidth of 2 nm. A scan...
Ngày tải lên : 20/02/2014, 01:20
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Tài liệu Báo cáo khoa học: A novel dicyclodextrinyl diselenide compound with glutathione peroxidase activity ppt

Tài liệu Báo cáo khoa học: A novel dicyclodextrinyl diselenide compound with glutathione peroxidase activity ppt

... selenolate and enhance the GPX-like activity of diselenides [11]. Although some GPX mimics show some increased activity, most show only limited catalytic enhancement. Based on an understanding of the ... the 6-CySeCD-cata- lyzed reduction of hydroperoxides by GSH and other species. One unit of enzyme activity is defined as amount of mimic that utilizes of 1 lmol of NAD...
Ngày tải lên : 19/02/2014, 02:20
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Tài liệu Báo cáo khoa học: FOXM1c transactivates the human c-mycpromoter directly via the two TATA boxes P1 and P2 docx

Tài liệu Báo cáo khoa học: FOXM1c transactivates the human c-mycpromoter directly via the two TATA boxes P1 and P2 docx

... immune and endocrine systems, components of signaling pathways and of the ubiquitin–proteasome pathway, and genes of tumor viruses. Activation of cell-cycle regulators, proto-oncogenes and genes involved ... binds to the P1 and P2 TATA boxes. (A, B) EMSAs were performed with radioactively labeled oligonucleotides P1 or P2 and with purified TBP and TFIIA or as control...
Ngày tải lên : 19/02/2014, 05:20
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Tài liệu Báo cáo khoa học: Aldehydes release zinc from proteins. A pathway from oxidative stress⁄lipid peroxidation to cellular functions of zinc pptx

Tài liệu Báo cáo khoa học: Aldehydes release zinc from proteins. A pathway from oxidative stress⁄lipid peroxidation to cellular functions of zinc pptx

... the etiology of cancer of the respiratory and digestive tracts, and in other diseases [10,32]. In summary, the reactivity of aldehydes with zinc proteins demonstrates that elevated levels of aldehydes affect ... thionein with acetaldehyde for 30 min, removing the excess of aldehyde with 1 unitÆmL )1 of yeast ADH, 2 mm NADH and 100 mm potassium chloride, and then assa...
Ngày tải lên : 19/02/2014, 06:20
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Tài liệu Báo cáo khoa học: "Large-Scale Syntactic Language Modeling with Treelets" docx

Tài liệu Báo cáo khoa học: "Large-Scale Syntactic Language Modeling with Treelets" docx

... sentences with a script that randomly deletes, inserts, or misspells a word; and Och et al. (2004) and Cherry and Quirk (2008) both use the 1-best output of a machine translation system. Examples of ... component of all speech recognition and machine translation systems, and a great deal of research centers around refining models (Chen and Goodman, 1998), ef- ficient stora...
Ngày tải lên : 19/02/2014, 19:20
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Tài liệu Báo cáo khoa học: "Improving Chinese Semantic Role Labeling with Rich Syntactic Features" ppt

Tài liệu Báo cáo khoa học: "Improving Chinese Semantic Role Labeling with Rich Syntactic Features" ppt

... put forward a number of new features to encode the structural information. Category of c k ’s parent; head word and POS of head word of parent, left sibling and right sibling of c k . Lexicalized ... rules: Conjuction of rewrite rule and head word of its corresponding RHS. These features of candidate (lrw-c) and its parent (lrw-p) are used. For example, this lrw- c fea...
Ngày tải lên : 20/02/2014, 04:20
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Tài liệu Báo cáo khoa học: "Expanding Verb Coverage in Cyc With VerbNet" doc

Tài liệu Báo cáo khoa học: "Expanding Verb Coverage in Cyc With VerbNet" doc

... relationship to Agent and Recipient is represented with the predicates giver and givee. The subject and oblique-object of the sentence fill those arguments, and the actual change of possession is ... frames 5 and they improved ResearchCyc parser performance by 20%. However, with 35% of frames in the VxC comparison and 16% in the parse test failing because of c...
Ngày tải lên : 20/02/2014, 04:20
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