... group of enzymes catalyzing the hydrolysis of alkyl and aryl epoxides into the corresponding vicinaldiols [1,2]. They fulfill various functions in hostorganisms, including detoxification by hydrolysis ... hydrolysis of endogenous and exogenous epoxides, regulation of cell signaling by hydrolysis of epoxide-containingbioactive lipids, or participation in the secondarymetabolism of microorganisms. In ... precursors in cutin synthesis [4]. The inde-pendence from cofactors in combination with, in some cases, high catalytic efficiencies and enantio-selectivities has created an interest in using epoxidehydrolases...