... bio-synthesis of DIMs and PGLs, the in vivo functions of these FadD proteins in this pathway remain to beestablished and ⁄ or completed. For instance, the involvement of FadD26 in the biosynthesis of pheno-lphthiocerol, ... becontrolled in vivo by specific interactions betweenFadD29 and PKS15 ⁄ 1 on the one hand, and FadD26 and the FasI system on the other hand. Further inves-tigations, including protein interaction ... PpsAduring DIM biosynthesis prompted us to examinewhether another FadD protein is specifically involved in the activation of the PpsA substrates during the formation of PGLs. Among the fadD...