... Regardless of dopamine treatment, overexpres-sion of a-synuclein significantly affected the levels of four proteins [stathmin 1, glutathione S-transferase(GST)p, Ran 1 binding protein and C1q binding ... suggested to be linked toearly stages of PD pathogenesis [26]. Interestingly, in our model, dopamine induces an increase of the actinbundles regulator fascin 1 [27] and discordant changes of two calcium-dependent, ... obtained from ppi spider starting from the proteins grouped as above (Tables S2 and S3). In both cases, bioinformatic analysis revealed thatthe NF-jB pathway could be involved in determiningthe...