Báo cáo khoa học: "Are These Documents Written from Different Perspectives? A Test of Different Perspectives Based On Statistical Distribution Divergence" ppt

... importantnatural language processing applications. Such a computational definition can be used to detectthe emergence of contrasting perspectives. Me-dia and political analysts regularly monitor broad-cast ... LinguisticsAre These Documents Written from Different Perspectives? A Test of Different Perspectives Based On Statistical Distribution DivergenceWei-Hao LinLanguage Technologies InstituteSchool of Computer ... of different perspectives will be very valuable to in-formation analysts.We first review the relevant work in Section 2.We take a model -based approach to develop a computational definition of...

Báo cáo khoa học: UDP-galactose 4-epimerase from Kluyveromyces fragilis – catalytic sites of the homodimeric enzyme are functional and regulated docx

... inhibition and secondary reactionsare not applicable for an enzyme, its deviation from the Michaelis–Menten relationship is a strong indication of allosteric regulation. Speciﬁc inactivation of onecatalytic ... UDP-Galbinding site indicates protection againsttrypsinization in the presence of UDP-Gal.All other notations are as in Scheme 1. A. Brahma et al. Regulation of catalytic sites of yeast epimeraseFEBS ... stated assay conditions, only the native epim-erase (E1) showed an initial lag in catalysis. The duration of lag (in seconds) was calculated from the time axis byextrapolating the linear...

Tài liệu Báo cáo khoa học: Evidence for noncooperative metal binding to the a domain of human metallothionein ppt

... columns (Amersham Bio-sciences ⁄ GE Healthcare, Piscataway, NJ, USA), superfineG-25 Sephadex (Pharmacia ⁄ Pfizer, Oakville, ON, Canada)and a stirred ultrafiltration cell (Amicon Bioseparations ⁄Millipore, ... investigated in thepast, primarily as in vitro metallation reactions with different MT isoforms and varying metal ions [16–21].Although most of these publications are from 10–20 years ago, these ... for a full description of theprotein preparation and purification details). Followingisolation and purification, the S-tag fusion peptide wascleaved from the domain, generating the isolateda...

Báo cáo khoa học: Nck-1 selectively modulates eIF2aSer51 phosphorylation by a subset of eIF2a-kinases docx

... eIF 2a- kinases is a general phe-nomenon, we also investigated the modulation of eIF 2a phosphorylation in conditions activating GCN2.As expected, amino acid starvation (deprivation of four amino acids) ... b-subunit of eIF2 [19]. In addition, we havereported that increased cellular levels of Nck stronglyimpair the phosphorylation of eIF2aSer51, attenuation of translation and polysomal dissociation that ... PKR and HRIactivation. By contrast, the overexpression of Nck in mammalian cells failsto attenuate eIF2aSer51 phosphorylation in response to amino acid starva-tion, a stress well known to activate...

Báo cáo khoa học: Well-deﬁned secondary structures Information-storing molecular duplexes and helical foldamers based on unnatural peptide backbones pot

... backbone could fold into well-definedand robust conformation based on backbone rigidification,could the same strategy of backbone rigidification beapplied to different unnatural backbones? Initial ... designed andsynthesized as complementary pairs with only one allowablemode of dimerization (Fig. 4). Initial indications of dime-rization were apparent as the solubilities of separatesolutions of ... unnaturalpeptide backbonesAdam R. Sanford, Kazuhiro Yamato, Xiaowu Yang, Lihua Yuan, Yaohua Han and Bing GongDepartment of Chemistry, University at Buffalo, State University of New York, Buffalo,...

Báo cáo khoa học: Examining multiprotein signaling complexes from all angles The use of complementary techniques to characterize complex formation at the adapter protein, linker for activation of T cells pdf

... acceptormust have a sufﬁcient spectral overlap, a favorable ori-entation and a separation of 1–10 nm [52]. Because of the ability of FRET to measure only close interactions,it is a valuable approach ... cellsJon C. D. Houtman, Mira Barda-Saad and Lawrence E. SamelsonLaboratory of Cellular and Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD, USAReversible ... form at the cytoplasmicdomain of transmembrane receptors, and at modularenzymes and nonenzymatic adapter proteins. Suchcomplexes are vital for the activation and propagation of intracellular...

Báo cáo khoa học: Natural-abundance isotope ratio mass spectrometry as a means of evaluating carbon redistribution during glucose–citrate cofermentation by Lactococcus lactis potx

... [11].esoculg 5.0etarticetavurypetatcalα etatcaloteca-etamrof A oC-lytecaHDANDAN+HDANDAN+niotecalytecaidP-lytecaetatecaHDANDAN+PDAPTAHDANDAN+PTAPDA124 a6 ,57b6389312101edyhedlatec a D A N+HD A NHDANDAN+lon a hte11HDANDAN+loid-3,2-n a tub7Fig. ... nonenzymaticdecarboxylation of a- acetolactate, whereas acetoin may bederived by either the nonenzymatic or the enzymaticdecarboxylation of a- acetolactate (Fig. 1). The high accu-mulation of ... Natural-abundance isotope ratio mass spectrometry as a means of evaluating carbon redistribution during glucose–citratecofermentation byLactococcus lactisMohamed Mahmoud, Emmanuel Gentil and...

Báo cáo khoa học: "Rare Word Translation Extraction from Aligned Comparable Documents" doc

... bilin-gual lexicon extraction from parallel corpora, rely-ing on the assumption that a word has one sense, onetranslation, no missing translation, and that its trans-lation appears in aligned parallel ... that our sys-tem can be trained on a pair of languages and test on a different pair of languages, obtain-ing a F-Measure of 77% for the classiﬁcation of Chinese-English translations using a ... learning approach. This approach consists of training a classiﬁer on positive examples of transla-tion pairs, and negative examples of non-translationspairs. The trained model (in our case, a...

Báo cáo khoa học: "Capturing Errors in Written Chinese Words" docx

... incorrect char-acters that are related to their pronunciations. They may use characters that could be pronounced exactly the same as the correct characters. They may also use characters that have ... propose characters that look similar to the correct character. Two characters may look similar for two reasons. They may contain the same components, or they contain the same radical and have ... experiments than using “Twn+Trad”. This observation may arouse a perhaps controversial argument. Although Taiwan has proclaimed to be the major region to use traditional Chinese, their web pages might...

Báo cáo khoa học: "Reformatting Web Documents via Header Trees" ppt

... is not anXML tag, but a header which is a part of documentthat can be regarded as tags annotated to other parts of the document. Titles, headlines, and attributes areexamples of headers. The ... where headers do notrepeat at all. Therefore, this type of algorithm maybe inadequate for the task of header extraction from arbitrary web documents. The remainder of this paper is organized as ... Deﬁnition of TermsOur system decomposes an HTML document into a list of blocks. A block is deﬁned as the part of a web document that is separated by a separator .A separator is a sequence of HTML tags...

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