... (13-methyl-[1,3]-benzodioxolo[5,6-c]-1,3-dioxolo-[4,5-i]-phenanthridinium chloride) (Fig. 1), a benzophenanthridine alkaloid derived from the plantSanguinaria canadensis, has been shown to have anti-microbial, anti-inflammatory, antioxidant, and anti-cancer ... micros-copy facility, and Dr Leslie Wilson, Dr Kamlesh Gupta,Manas Kumar Santra, K Rathinasamy and RenuMohan for critical reading of the manuscript. The workis partly supported by grants (to D.P.) ... Bcl-2 family proteins andmitochondrial apoptosis pathway by sanguinarine inimmortalized human HaCaT keratinocytes. Clin CancerRes 9, 3176–3182.25 Adhami VM, Aziz MH, Reagan-Shaw SR, Nihal M,Mukhtar...