Báo cáo khoa học: The equinatoxin N-terminus is transferred across planar lipid membranes and helps to stabilize the transmembrane pore pot

Báo cáo khoa học: The equinatoxin N-terminus is transferred across planar lipid membranes and helps to stabilize the transmembrane pore pot

Báo cáo khoa học: The equinatoxin N-terminus is transferred across planar lipid membranes and helps to stabilize the transmembrane pore pot

... Journal compilation ª 2006 FEBS The equinatoxin N-terminus is transferred across planar lipid membranes and helps to stabilize the transmembrane pore Katarina Kristan 1 , Gabriella Viero 2 , Peter ... contacts is between the monomers, which should stabilize the toroidal pore [19]. Thus, the purpose of this work was to gain further insight into th...
Ngày tải lên : 23/03/2014, 10:20
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Báo cáo khoa học: Identification of yeast aspartyl aminopeptidase gene by purifying and characterizing its product from yeast cells potx

Báo cáo khoa học: Identification of yeast aspartyl aminopeptidase gene by purifying and characterizing its product from yeast cells potx

... pre- cursor, they are probably located in the cytosol. There- fore, aspartyl aminopeptidase activity may be related to the metabolism of cytosolic peptides, particularly during the final step in their ... belong to the M18 family of metal- loprotease, comprise 12 identical subunits, and the activity of these enzymes is inhibited by EDTA [4,5]. These two enzymes may be related...
Ngày tải lên : 07/03/2014, 12:20
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Báo cáo khoa học: An antimicrobial peptide tachyplesin acts as a secondary secretagogue and amplifies lipopolysaccharide-induced hemocyte exocytosis potx

Báo cáo khoa học: An antimicrobial peptide tachyplesin acts as a secondary secretagogue and amplifies lipopolysaccharide-induced hemocyte exocytosis potx

... exocytosis [12,16]. This exocy- tosis reaction is important for the host defense ability to engulf and kill invading microbes; hemolymph coagulation prevents the leakage of hemolymph and the spread ... interacts with G protein and receptor- independently induces the exocytosis of mast cells [22]. Previously, we found that mastoparan is able to induce the exocytosis of...
Ngày tải lên : 30/03/2014, 20:20
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Tài liệu Báo cáo khoa học: Olfactory receptor signaling is regulated by the post-synaptic density 95, Drosophila discs large, zona-occludens 1 (PDZ) scaffold multi-PDZ domain protein 1 pptx

Tài liệu Báo cáo khoa học: Olfactory receptor signaling is regulated by the post-synaptic density 95, Drosophila discs large, zona-occludens 1 (PDZ) scaffold multi-PDZ domain protein 1 pptx

... antibodies. Immunohistochemistry Mice were raised and maintained according to governmen- tal and institutional care instructions. Immunohistochemis- try was carried out on 14 lm horizontal sections, and fluorescence ... mammals to detect and discriminate between thou- sands of different odorant molecules is governed by the diverse array of olfactory receptors expressed by olfac...
Ngày tải lên : 18/02/2014, 13:20
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Tài liệu Báo cáo khoa học: Rotary F1-ATPase Is the C-terminus of subunit c fixed or mobile? docx

Tài liệu Báo cáo khoa học: Rotary F1-ATPase Is the C-terminus of subunit c fixed or mobile? docx

... c and the complete a-helical C-terminus as held within the top of (ab) 3 . The rotary axis z was aligned along the main axis of the shaft. The ‘bearing’ included a total of 138 residues from the ... on the two groups of four carbon atoms each. The first group included the C a atoms of cK18, cI19, cT20 and cK21, and the second group C a atoms of cD233, cN234, cA235...
Ngày tải lên : 19/02/2014, 16:20
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Báo cáo khoa học: Arabidopsis thaliana CYP77A4 is the first cytochrome P450 able to catalyze the epoxidation of free fatty acids in plants potx

Báo cáo khoa học: Arabidopsis thaliana CYP77A4 is the first cytochrome P450 able to catalyze the epoxidation of free fatty acids in plants potx

... that the regioselectivity and enantioselectivity of epoxidation are cytochrome P450 dependent [37,38]. For CYP77A4, the requirement of unsaturation, in the cis configuration, together with the ... plants, and only a few biological activities have been attributed to them. The discovery of such activities in plants might help to understand the physi- ological role of CYP77A4....
Ngày tải lên : 07/03/2014, 03:20
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Báo cáo khoa học: Neuroserpin Portland (Ser52Arg) is trapped as an inactive intermediate that rapidly forms polymers Implications for the epilepsy seen in the dementia FENIB ppt

Báo cáo khoa học: Neuroserpin Portland (Ser52Arg) is trapped as an inactive intermediate that rapidly forms polymers Implications for the epilepsy seen in the dementia FENIB ppt

... inserted into its own b-sheet A to form a latent conformer [16]. However, this is unlikely as the latent conformer of the serpins is unable to form polymers [17,18]. Other charac- teristics of the latent ... [1,8]. This contrasts with other conditions such as Parkinson’s and Huntington’s disease in which the mutant proteins form disordered aggregates within the cytoplasm [...
Ngày tải lên : 07/03/2014, 16:20
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Báo cáo khoa học: Androgen receptor function is modulated by the tissue-specific AR45 variant ppt

Báo cáo khoa học: Androgen receptor function is modulated by the tissue-specific AR45 variant ppt

... of cofactors and adrenal androgen The absence of stimulatory activity of AR45 might be linked to poor coactivator recruitment, due to the absence of the NTD. This might be overcome by the overexpression ... found in the regulatory regions of their target genes [14]. Due to the involvement of these receptors in several major diseases, extensive research has been carried out...
Ngày tải lên : 07/03/2014, 16:20
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Báo cáo khoa học: b-Secretase cleavage is not required for generation of the intracellular C-terminal domain of the amyloid precursor family of proteins pot

Báo cáo khoa học: b-Secretase cleavage is not required for generation of the intracellular C-terminal domain of the amyloid precursor family of proteins pot

... APP 695 -expressing cells is due to the fact that the epitope for the antibody against rodent Ab is not present in human APP (Table 1), whereas the absence of this band in the APP KO extract confirms the specificity ... samples (Fig. 1C). As the band migrating at  94 kDa was rec- ognized by antibodies directed to both the ectodomain and the C-terminus, this band app...
Ngày tải lên : 15/03/2014, 10:20
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Báo cáo khoa học: Sp3 transcription factor is crucial for transcriptional activation of the human NOX4 gene doc

Báo cáo khoa học: Sp3 transcription factor is crucial for transcriptional activation of the human NOX4 gene doc

... Sp1 and Sp3 are the major transcription factors that bind to GC-boxes 1 and 2 in the NOX4 promoter. In vivo binding of Sp1 and Sp3 to GC-boxes 1 and 2 in the NOX4 promoter To examine whether ... Sp1 and Sp3 to GC-boxes 1 and 2 in the NOX4 promoter The GC-box is known to bind Sp ⁄ Klf transcription factors, especially Sp1, Sp3 and Sp4 [14,15]. To exam- ine...
Ngày tải lên : 29/03/2014, 00:20
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