Báo cáo khoa học: The crystal structure of the ring-hydroxylating dioxygenase from Sphingomonas CHY-1 pot
Báo cáo khoa học: MR solution structure of the precursor for carnobacteriocin B2, an antimicrobial peptide fromCarnobacterium piscicola Implications of the a-helical leader section for export and inhibition of type IIa bacteriocin activity pdf
... establish the preferred geometry of the precursor. We now report the chemical synthesis, bio-chemical production, and solution structure of preCbnB2,and compare it with the structure of the maturebacteriocin, ... Solution structure of preCbnB2 in 70% trifluoroethanol. The positions of the N-terminus and C-terminus are indicated, as are the residues at the start and finish of each a-helix. The position of the double ... purple.Fig. 4. Superimposition of preCbnB2 structures. (A) Superimposition of the backbone of the leader peptide a-helix for 20 structures. (B)Superimposition of the backbone of helix 2. Both helix...
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Báo cáo khoa học: Monomeric solution structure of the helicase-binding domain of Escherichia coli DnaG primase pdf
... Stereo views of the solution and crystal structures of DnaG-C. (A) Superposi-tion of the backbone atoms of residues447–581 of the 20 NMR conformers of DnaG-C representing the NMR structure (Table ... andboundaries of helix 6 (Fig. 3D,E), showing that thishelix can be separated from the core of the structure. The solution structure of DnaG-C identifies the crystal Fig. 2. Sequence alignment of DnaG-C ... (D) Con-former I of the crystal structure dimer of E. coli DnaG-C [4]. (E) Conformer II of the crystal structure dimer of E. coli DnaG-C [4].X C. Su et al. Solution structure of E. coli DnaG-CFEBS...
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Báo cáo khoa học: X-ray structure of glucose/galactose receptor from Salmonella typhimurium in complex with the physiological ligand, (2R)-glyceryl-b-D-galactopyranoside pdf
... This kind of protein is exemplified by the Thermus thermophilus protein, PDB entry 2B3B [28]. The mode of binding the monosaccharide is completelydifferent in terms of orientation of the sugar, ... similarity between the Fig. 3. Extension of the GGal site. Stereo-view of the residues lining the water-filledtunnel that extends from the glyceryl moietyto the surface of GBP are shown.S. ... blue).Domain 1 of the two structures is superimposed. (B) Superposition of domain 1 in the available GBP structures from Salmonella andE. coli. The structures are colored progressing from blue (mostclosed)...
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Báo cáo khoa học: Change in structure of the N-terminal region of transthyretin produces change in affinity of transthyretin to T4 and T3 pdf
... evolution of the primary structure of the N-terminal regions of TTR and the biologicalfunction of TTR.ResultsSynthesis of recombinant human TTRIn the crocodile, TTR is only synthesized in the liverduring ... T4). In the other, the N-terminal region of crocTTR was deleted. The affinity of T3 and T4 to both TTRs was studied and the results are a powerful demonstration of the rela-tionship between the evolution ... that the N-terminal regions of TTR affect the affinities of TTR for thyroid hormones. A previousstudy revealed that altering the structure of the N-ter-minal region influenced the affinity of thyroid...
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Tài liệu Báo cáo khoa học: Salt-induced formation of the A-state of ferricytochrome c – effect of the anion charge on protein structure docx
... for the formation of the A-state from acid-denatured cytochrome c,as the A-state possesses a native-like a-helix structure [11,17]. Figure 1 shows the gradual recovery of the ordered secondary structure ... that the variants undergo very fast optical (and thus structural)changes within the dead time of the stopped-flowapparatus. In the case of the K13N mutant, this hypo-thesis finds support from the ... Effect of sulfate (s) and selenate (. ) concentration on the heme pocket environment [and on the strength of the Met80–Fe(III) axial bond] of the salt-induced A-state of cytochrome c,asobserved from...
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Báo cáo khoa học: NMR solution structure of Cn12, a novel peptide from the Mexican scorpion Centruroides noxius with a typical b-toxin sequence but with a-like physiological activity doc
... (ENa¼)65). To determine the amplitude of the toxin-induced slowinactivation, we subtracted the control traces from the tracesrecorded in the presence of the toxin. The amplitude of thesetoxin-induced ... a clear cut separation of all the b Na-ScTxs from all the a Na-ScTxs. The a Na-ScTxs have identities of the order of 50% among themselves, the same being true for all the b Na-ScTxs (data not ... organism (e.g. the ratbrain isoform rNaV1.1 is 10-fold more sensitive to the action of the a Na-ScTx Lqq5 than the cardiac isoform rNaV1.5[67]). However, when the overall charge of both the toxinsand...
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Báo cáo khoa học: Three-dimensional structure of a thermostable native cellobiohydrolase, CBH IB, and molecular characterization of the cel7 gene from the filamentous fungus, Talaromyces emersonii ppt
... beaccommodated. The b-sandwich represents the characteris-tic fold of GH7 and is a lso the fold of the l egume-lectinfamily and of GH16 [57]. The loops extending from the b-sandwich are stabilizedby the ... hold the b-sandwich in position. With the exception of four a-helices and t wo pairs of short b-strands, the rest of the protein consists almost entirely of loopsconnecting the b-strands. The ... analysisPeptides sequenced from native CBH I B confirmed the identity of the T. emersonii cel7 gene/gene product; the location of these peptides in the deduced polypeptidesequence is given in the legend to...
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Báo cáo khoa học: H NMR study of the molecular structure and magnetic properties of the active site for the cyanomet complex of O2-avid hemoglobin from the trematode Paramphistomum epiclitum pdf
... away from the heme normal (z¢ axis),a is the angle between the projection of the tilt of the z axis on the x¢,y¢ plane (defined direction of tilt of z and the x¢ axis), and j % a + c defines the location ... ligand.Comparison of the strengths of dipolar interactions insolution with the alternate crystal structures of methemo-globin establish that the solution structure of wild-type Hbmore closely resembles the ... por-tions of the protein that we have characterized above.Thus parts of the FG corner move away from the hemeand the B-helix moves closer to the heme in the WTmetHbthanintherWTmetHbH2O crystal structure, with...
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Báo cáo khoa học: Inhibitor-mediated stabilization of the conformational structure of a histone deacetylase-like amidohydrolase pptx
... refolding of HDAH The crystal structure of HDAH contains one Zn2+ionat the bottom of the active site and two K+ions in the neighbourhood of the active site [13]. The import-ance of Zn2+and ... interactions of the aliphaticchains with Phe152 and Phe208, are believed to con-tribute to the stabilization of the the major part of the conformational structure of HDAH [13]. The meqvalue of free ... [33]. The free energy of unfolding (DGu) from the intermediate to the denatured and the parameter meqwere obtained from fitting the data of the equilib-rium denaturation curve to Eqn (1). The...
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Tài liệu Báo cáo khoa học: An autoinhibitory effect of the homothorax domain of Meis2 ppt
... positions of molecular mass markers are shown to the left,and the size in base pairs of the products to the right (the Meis2 equivalent of Meis3.2 would be expected at 149 bp). (C, D) RNA from aseries ... However, the activity of the full-length Meis1awas not tested, and on the basis of our work we expectthat its activity would be inhibited by the conservedHth domain. The Meis1a isoform, in which the C-terminal ... independently of Pbx, and does notpossess the autoinhibitory function of the Hth domain.In summary, our data suggest that one function of the conserved Hth domain is to inhibit the activity of the transcriptional...
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Từ khóa: chuyên đề điện xoay chiều theo dạngNghiên cứu tổ chức pha chế, đánh giá chất lượng thuốc tiêm truyền trong điều kiện dã ngoạiGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitQuản lý hoạt động học tập của học sinh theo hướng phát triển kỹ năng học tập hợp tác tại các trường phổ thông dân tộc bán trú huyện ba chẽ, tỉnh quảng ninhPhát triển mạng lưới kinh doanh nước sạch tại công ty TNHH một thành viên kinh doanh nước sạch quảng ninhNghiên cứu, xây dựng phần mềm smartscan và ứng dụng trong bảo vệ mạng máy tính chuyên dùngNghiên cứu tổng hợp các oxit hỗn hợp kích thƣớc nanomet ce 0 75 zr0 25o2 , ce 0 5 zr0 5o2 và khảo sát hoạt tính quang xúc tác của chúngNghiên cứu khả năng đo năng lượng điện bằng hệ thu thập dữ liệu 16 kênh DEWE 5000Quản lý nợ xấu tại Agribank chi nhánh huyện Phù Yên, tỉnh Sơn La (Luận văn thạc sĩ)Tăng trưởng tín dụng hộ sản xuất nông nghiệp tại Ngân hàng Nông nghiệp và Phát triển nông thôn Việt Nam chi nhánh tỉnh Bắc Giang (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtchuong 1 tong quan quan tri rui roGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtBÀI HOÀN CHỈNH TỔNG QUAN VỀ MẠNG XÃ HỘIHIỆU QUẢ CỦA MÔ HÌNH XỬ LÝ BÙN HOẠT TÍNH BẰNG KIỀMQUẢN LÝ VÀ TÁI CHẾ NHỰA Ở HOA KỲ