... [12,14,15,19,20,22],there are no reports on the true nature of the RGD-containing proteins and their interacting partners. The involvement of the PLDa C2 domain in theseFig. 7. C2 domain is degraded by cardosin ... at the tip of a loop protruding away from the core of the protein. This amino-acid motif mimics RGD in terms of charge and is positioned at the tip of a loop and istherefore reminiscent of RGD ... at the surface of the protein [4]. The presence of this well-known integrin-binding motif [11], and the previouspurification of a cardosin A-binding protein from pol-len, raised the idea that...