Báo cáo khoa học: The crystal structure of a xyloglucan-specific endo-b-1,4glucanase from Geotrichum sp M128 xyloglucanase reveals a key amino acid residue for substrate specificity potx
... picolinic
acid (PA), quinolinic acid (QA) and NAD homeostasis. Indeed, the enzyme
stands at a branch point of the tryptophan to NAD pathway, and deter-
mines the final fate of the amino acid, i.e. transformation ... by the action of
ACMS decarboxylase (ACMSD, also known as picoli-
nate carboxylase; EC 4.1.1.45) into a- aminomuconic
Keywords
cerebral malaria; kynurenin...
... 5¢-AGATCTTATCACTCCCTTACTAAGTCGATG-3¢
for the b subunit and 5¢-CATATGAGCGAGAAAACCA
TGCGCGTGCAG-3¢ and 5¢-AGATCTTAGCTTCCTTT
ACGCAGCTTATGC-3¢ for the c subunit. The segments
were digested with NdeIandBglII ... Poznanskaya, A. A., Yakusheva, M.I. & Yakovlev, V .A. (1977)
Study of the mechanism of action of adenosylcobalamin-depen-
dent glycerol dehydratase from Aerobacter...
... 5¢-aataatccatggggagtaatacttcctggcgta
aaagtgaagtcc-3¢ and 5¢-attattggatccctattgctggtccgattctgccag-3¢.
3-TPR NlpI primers (residues 62–197) were 5¢-aataatccatgg
gggcacagcttttatatgagcgcggag-3¢ and 5¢-aataatggatcctcactgttc
cttatccgatttttcgaagtgc-3¢. ... responsible for the sharp curvature of the array and
reduced superhelical pitch, leading to the formation of a globular structure....
... [1–4].
Mammalian annexins A1 [5], A5 , and A 6 [6], as well as
plant annexins from Medicago sativa [7] and Arabidop-
sis thaliana [8,9], have been implicated in oxidative stress
response. In particular, ... annexin Anx24(Ca32), but significant differences
are seen when compared to the structure of nonplant
annexins. A comparison with the structure of the mamma-
lian annexi...
... on relaxation
matrix calculations, was used to back calculate the NOESY
cross-peaks from the calculated structure to assess the
quality of the structure.
The final family was made up of 30 structures ... and compared with that of
oxidized human SOD. All the metal ligands are well defined
in a single conformation. For all the ligands, the rmsd value
calculated for...
... Tsuruga and Shikama [21] confirmed
that the fast phase of oxidation was due to the a chains and
the slow phase was due to the bchains. Tsuruga et al. found
that the beta chain of the tetramer does ... auto-oxidation of Hb A
0
has been
the subject of several studies. Mansouri and Winterhalter [5]
reported that the oxidation of the a chains of Hb A
0
was 10...
... phosphorylation. The data presented here suggest that the
pro-domain of BMP-2 can alter the signalling properties of the growth factor
by modulating the ability of the mature part to interact with the ... [16]. In the case of BMP-9, the pro-pep-
tide appears not to alter significantly the activity of the
mature part [17]. For the pro-peptide of BMP-7, a...
... Edmonton, AB, Canada
Type IIa bacteriocins, which are isolated from lactic acid
bacteria that are useful for food preservation, are potent
antimicrobial peptides with considerable potential as
therapeutic ... specificity similar to
the mature type IIa bacteriocin.
The leader peptide, which consists of the first 18 amino
acids of PreCbnB2(1–64), forms a 10 -amino acid a...
... mixture of species at
both concentrations. The average M
r
was calculated by
linear regression using ultrascan data analysis software
Version 5 (Beckman Coulter), and an (assumed) partial
specific ... replication of the leading strand and synthesis of
the Okazaki fragments is initiated by RNA primers
made by the specialized RNA polymerase, primase.
The first primase to be identi...
... iMDsoft,
Sassenheim, The Netherlands) and searched the hospital
information system for the following: orders for sputum cul-
tures or performance of a bronchoalveolar lavage for culture,
or start ... clinical decision
making in the ICU. In that study, a questionnaire was com-
pleted for each radiograph, addressing the indication for the
radiograph and whether it ch...