A Single-Molecule Perspective on the Role of Solvent Hydrogen Bonds in Protein Folding and Chemical Reactions pptx

... rupture of a pair of hydrogen bonds in the A and B b-strands near the amino terminus of the protein domain causes an initial extension of the protein, before the unfolding transition state is reached.[53] The ... bridging the A and G b-strands of the I27 protein during the main unfold-ing barrier.[39]To further validate this view and gain insight into the role of solvent hydrogen bonds in protein unfolding, ... bond engineered within a single pro-tein. Altogether, these experiments provide new information on the nature of the underlying interactions in protein folding and chemical reactions and demonstrate...

What Changes Are Being Made to Social Assistance Benefits: A Community Perspective on the Impact of these Changes. pdf

... municipal decision-making;  discover what provincial and local actions are taking place in response to the changes;  have a chance to say what the changes will mean for people on Ontario ... Breastfeeding can help to keep families together because the CAS is less willing to take a baby from a mother who is breastfeeding. Breastfeeding saves a huge amount of money, and can continue ... from a father who is work-ing.  Single mothers on assistance are afraid that they will lose their benefits because they will not be able to afford the cost of testing and therefore they won’t...

Báo cáo khoa học: Concepts and tools to exploit the potential of bacterial inclusion bodies in protein science and biotechnology pdf

... misincorporation,premature chain truncation and incomplete modiﬁca-tions. Such aberrant molecules accumulate in the cyto-plasm and increase protein aggregation [14]. In general, mutations are retained only ... principal biophysical methods available for the characterization of proteins aggregated in IBs and summarize the information generated by their applica-tion (Fig. 2). The aggregation of recombinant ... native a- helices of the N-terminal 185 residues of the functional domain of the HA2 subunit of the in uenza virus hemagglutinin protein and to detectconformational heterogeneity of the protein...

Báo cáo khoa học: What’s in a covalent bond? On the role and formation of covalently bound flavin cofactors doc

... the formation of these covalent bonds. The amino acidsthat are involved in specific interactions with the flavinring system and may facilitate formation of the cova-lent protein flavin bond are ... on elucidating the mechanism(s) of covalent flavin incorporation (flavinyla-tion) and the possible role( s) of covalent protein flavin bonds. Theseendeavors have revealed that covalent flavinylation is a ... described above, mainly histidyl–FAD-containing enzymes, it appears that the func-tional benefit of acquiring and retaining a covalentflavin protein link is to increase the redox potential and thus also...

A CFD analysis on the effect of ambient conditions on the hygro-thermal stresses distribution in a planar ambient airbreathing PEM fuel cell

... humidity. As a result of in the changes in temperature and moisture, the membrane, GDL and bipolar plates will all experience expansion and contraction. Because of the different thermal expansion and ... meeting two conflicting needs: adequate membrane hydration and avoidance of water flooding in the cathode catalyst layer and/ or gas diffusion layer [2]. Water management is related with air ... displacement and the degree of the deformation in membrane are directly related to the increasing of ambient temperature and decreasing of relative humidity, due to increasing of heat generation. ...

Tài liệu A Case Study on the Implementation of A Knowledge Management Strategy Oriented to Innovation pdf

... externalsources; the integration of internal and externalknowledge and its application to problem solving; the creation of new knowledge and the generation of innovations from this integration, and ... that is, an interactionbetween actions and behaviors. The action of creation does not consist of the processing of infor-mation or data, since the obtaining of tacit knowl-edge, which cannot ... view of the ﬁrm, as an overall change process and a form of organisational renewal, focused on innovation,through the creation, transmission and application of new knowledge (Cohen and Levinthal,...

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A STUDY ON THE TRANSLATION OF ENGLISH COMPUTER TEXTS IN VIETNAMESE EQUIVALENTS

... with the central concepts in translation incorporating translation theory, translation equivalence, translation methods and procedures, technical translation and translation in the field of computer ... Different linguists have put the definition of translation in various ways, among which the followings stand out. “Translation is the expression in another language (or target language) of what has ... saying the main division in the translation field is between literary and technical translation”. As he puts it, “one way of defining technical translation is by asking the question, does the...

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Tài liệu A Historical Primer on the Business of Credit Ratings docx

... question is that the agencies gather and analyze all sorts of pertinent financial and other information, and then use it to provide a rating of the intrinsic value or quality of a security as a ... guarantors of the assets. Agency bond ratings could be used as one way of constraining the asset managers from acting in such a way. As Martin Fridson, a proponent of this newer view of the independent ... exist among the owners of financial assets, the institutions (both public and private) that guarantee the assets, and the asset managers that act as agents for the principals or owners. An asset...

Tài liệu A REVIEW OF INDOOR AIR POLLUTION AND HEALTH PROBLEMS FROM THE VIEWPOINT OF ENVIRONMENTAL HYGIENE: FOCUSING ON THE STUDIES OF INDOOR AIR ENVIRONMENT IN JAPAN COMPARED TO THOSE OF FOREIGN COUNTRIES pptx

... Kamijima, M., Sh ib ata, E., Ohn o, H. and Nakajima, T. (2009) Annual transition and seasonalvariation of indoor air pollution levels of 2-ethyl-1-hexanol in large-scale buildings in Nagoya, Japan.J. ... by the “Act for Maintenance of Sanitation in Buildings”;however, small buildings and individual residencesare not included, and the substances in indoor air and their concentrations from the ... phthalate (DEHP)among phthalates were detected predominantly in indoor air samples.93) The dominant path of phtha-lates intake was the ingestion of foodstuffs com-pared to inhalation of indoor...

Tài liệu Báo cáo khoa học: "From HOPE en I''''ESPERANCE On the Role of Computational Neurolinguistics in Cross-Language Studies " pptx

... ASSUMPTIONS IN HOPE HOPE is not an acronym but was chosen as the name of the system based on the legend of Pandora's box. While raising many questions of language within a new computational perspective, ... value, initially at a resting state, that is modified over time depending on the input, interconnections to other information, and an automatic activity decay scheme. In addition, the decay ... INTERPRETATION is a result of acti- vation of a pragmatic representation of a disambiguated word meaning. It is the in interaction of the results of these asynchronous processes that the process of comprehension...

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