Báo cáo khoa học: R120G aB-crystallin promotes the unfolding of reduced a-lactalbumin and is inherently unstable ppt
Tài liệu Báo cáo khoa học: MicroRNA-23a promotes the growth of gastric adenocarcinoma cell line MGC803 and downregulates interleukin-6 receptor pdf
... miR-23apotently promotes the growth of the gastric adeno-carcinoma cell line MGC803, providing the first proof- of- concept that there is a potential link between the tumor promoter miR-23a and gastric ... Institute and Hospital and the National Foundation of Cancer Research. All of the tumor types were confirmedby pathologic analysis. The experiments were undertakenwith the understanding and written ... China), and all otherswere obtained from Sigma-Aldrich (St Louis, MO, USA).Statistical analysis The data were expressed as the means ± standard devia-tion (SD) and statistical analysis utilized...
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Tài liệu Báo cáo khoa học: Aggregative organization enhances the DNA end-joining process that is mediated by DNA-dependent protein kinase pdf
... irrespective of the presence of the supernatant from the initial centrifugation, the yield of EJ products did not appreciably change (com-pare lanes 1 and 2). The replacement of the superna-tant ... DNA in the absence of Ku and predominantly forms a large com-plex without any mobility shift in the well of the gel[31]. The stability of the complex against salt is alsoenhanced by the presence ... the action mode, the role of the N-terminal portion of nucleolin is suggestive.This region includes the basic and repeated octapep-tides that are similar to histone H1 [28] and acidicstretches...
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Tài liệu Báo cáo khoa học: Inorganic phosphate regulates the binding of cofilin to actin filaments pdf
... University of Jerusalem, Israel2 Department of Chemistry and Biochemistry and the Molecular Biology Institute, University of California, USAActin dynamics, the polymerization and depolymeriza-tion of ... actin protomers locatedin the vicinity of the barbed end of the filament, pro-ducing an ATP or ADP–Pi cap at this end. Because of the presence of this cap at the barbed end the criticalconcentration ... inhibitory effect of Pi on the subtilisin digestionindicates stabilization of the D-loop.Monitoring the binding of cofilin to F-actin bylimited proteolysis The effect of Pi on the binding of cofilin...
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Tài liệu Báo cáo khoa học: Final steps in the catabolism of nicotine Deamination versus demethylation of c-N-methylaminobutyrate doc
... completing the catabolism of the pyrrolidine moiety of nicotine.Expression of the genes of these enzymes was dependent on the presence of nicotine in the growth medium. Thus, two enzymes of the nicotine ... in this study and RT-PCR analysis of transcripts. (A) Schematic representation of the pAO1 gene and ORFcluster flanked by Tn554 and DTn. The cluster consists of the pmfR gene, encoding the regulator ... understanding of the enzymology of nicotine catabolism is required.Our effort is directed towards the comprehensivecharacterization of the metabolic pathways of nicotinebreakdown as it is present...
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Tài liệu Báo cáo khóa học: Further insights into the assembly of the yeast cytochrome bc1 complex based on analysis of single and double deletion mutants lacking supernumerary subunits and cytochrome b pdf
... caused the loss of the othertwo subunits. This is consistent with the crystal structure of the cytochrome bc1complex that shows that these threesubunits comprise its core, around which the remainingsubunits ... on the left side of the blots. The Westernblots are shown in panels A and B and the relative amounts of each of the subunits determined by densitometry scanning of the stained Westernblots of ... is one of the two respiratoryTable 3. Cytochrome bc1subunit analysis of single deletion mutants. The values represent the percentages of the amounts of the individualsubunits present in the...
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Tài liệu Báo cáo khoa học: Oxygen tension regulates the expression of a group of procollagen hydroxylases docx
... fully support these previous findings and on the otherhand extend them by far and set them in a more generalcontext, as both a-subunits of P4h, PDI as the b-subunit of P4h [13] and the collagen ... [29] and also for the keyplayers of angiogenesis [30].Considering the parallel up-regulation of enzymesinvolved in collagen fiber formation raises the question of whether this up-regulation is ... characteristic time-dependentfive- to 12-fold up-regulation of the mRNAs of the two P4ha-subunits [aI (P4ha1) and aII (P4ha2)] and of two lysyl-hydroxylases (PLOD1 and PLOD2). These effects of hyp-oxia...
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Tài liệu Báo cáo khoa học: Proteasome involvement in the degradation of the Gq family of Ga subunits pptx
... loadedwith the 35S immunoprecipitates and the arrowheads indicate the position of Gaq and Ga16. The molecular mass standards areindicated. The arrow indicates the position of some unspecific bands.Proteasome ... ormaturation of the protein. An increase was alsoobserved in the rate of degradation of the remainingmutant protein (20% left of the protein) vs. the wildtype (40% left of the protein) at 3 h of chase(Fig. ... DNA:pCISGaqor pCISGa16in presence or absence of pCISM1Ror pCISM2R ⁄ pCISC5aR (Ga ⁄ R ¼ 0.4 ⁄ 0.6), respectively. The total amount of DNA was kept constant with the addi-tion of pCISLacZ.Metabolic...
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Tài liệu Báo cáo khoa học: Multidentate pyridinones inhibit the metabolism of nontransferrin-bound iron by hepatocytes and hepatoma cells docx
... overloadconditions, and is also implicated in intracellular Femetabolism [3,9,10]. An important aspect of this workwas the assessment of the effect of novel Fe chelators on the uptake and fate of NTBI and ... to the obligatory treatment of the anemia with bloodtransfusions. The contribution of plasma NTBI to the toxicity associated with Fe overload in these disorders is uncertain, as is the form of ... 1693Effect of chelators and Fe status on subcellular distribu-tion of NTBI in hepatocytes. The effect of the chelators on the intracellular distribution of Fe in normal and Fe-loadedhepatocytes in the...
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Tài liệu Báo cáo khoa học: Adaptive changes in the expression of nuclear and mitochondrial encoded subunits of cytochrome c oxidase and the catalytic activity during hypoxia pptx
... tested the level of mRNA for subunit VIIa,which is expressed as isolog H and L. The L isolog is ubiquitously expressed in all the tissues whereas the H isolog is detected in the heart and skeletal ... switch and alters the expression of the twonuclear genome coded isoforms of CytOX V [10,32]. The regulation of genes CytOX5a and CytOX5b, coding for the two isofoms Va and Vb, parallels that of ... Table 2, there was a markeddifference in the total cell ATP synthesis as well asmitochondrial respiration-coupled ATP synthesis inmacrophages and PC12 cells. The rate of ATP synthesisin control...
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Tài liệu Báo cáo khoa học: "Detecting Novel Compounds: The Role of Distributional Evidence" potx
... corpus is indicative of their terminological sta-tus, and has not addressed the issue of discovering terms when data is sparse.This becomes apparent in the case of noun compounding, which is extremelyproductive: ... the BNCmore than once (CoocF > 1) the heuristic's accu-racy is increased by 11.0%. However, the number of potential compounds is reduced by a factor of three. The majority of the candidate ... terms. The main assumption underlying the statisticalapproach to term acquisition is that lexically as-sociated words tend to appear together more of- ten than expected on the basis of their...
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Từ khóa: Báo cáo quy trình mua hàng CT CP Công Nghệ NPVchuyên đề điện xoay chiều theo dạngMột số giải pháp nâng cao chất lượng streaming thích ứng video trên nền giao thức HTTPGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitNGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN SLIDETrả hồ sơ điều tra bổ sung đối với các tội xâm phạm sở hữu có tính chất chiếm đoạt theo pháp luật Tố tụng hình sự Việt Nam từ thực tiễn thành phố Hồ Chí Minh (Luận văn thạc sĩ)Phát hiện xâm nhập dựa trên thuật toán k meansNghiên cứu, xây dựng phần mềm smartscan và ứng dụng trong bảo vệ mạng máy tính chuyên dùngĐịnh tội danh từ thực tiễn huyện Cần Giuộc, tỉnh Long An (Luận văn thạc sĩ)Tìm hiểu công cụ đánh giá hệ thống đảm bảo an toàn hệ thống thông tinThiết kế và chế tạo mô hình biến tần (inverter) cho máy điều hòa không khíChuong 2 nhận dạng rui roTổ chức và hoạt động của Phòng Tư pháp từ thực tiễn tỉnh Phú Thọ (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtchuong 1 tong quan quan tri rui roNguyên tắc phân hóa trách nhiệm hình sự đối với người dưới 18 tuổi phạm tội trong pháp luật hình sự Việt Nam (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtTrách nhiệm của người sử dụng lao động đối với lao động nữ theo pháp luật lao động Việt Nam từ thực tiễn các khu công nghiệp tại thành phố Hồ Chí Minh (Luận văn thạc sĩ)TÁI CHẾ NHỰA VÀ QUẢN LÝ CHẤT THẢI Ở HOA KỲ