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Báo cáo khoa học: Cooperation of two carotene desaturases in the production of lycopene in Myxococcus xanthus pot

Tài liệu Báo cáo khoa học: An engineered disulfide bridge mimics the effect of calcium to protect neutral protease against local unfolding docx

Tài liệu Báo cáo khoa học: An engineered disulfide bridge mimics the effect of calcium to protect neutral protease against local unfolding docx

... Ger-many). The amount of intact protein was calculated from the intensity of the protein band.Autoproteolysis in sample solutions containing <20lgÆmL)1protein was followed by determining the ... the introduction of the disulfide bridge (at5mm CaCl2and 25 ° C) is obtained. The in uence of calcium ions on the unfoldingkinetics The in uence of the calcium ion concentration onunfolding ... variant with a mutation in the vicinity of cal-cium binding-site III (W55F) is included in the studies. The results indicate two competing routes of auto-proteolysis, one starting from locally unfolded...
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Tài liệu Báo cáo khoa học:

Tài liệu Báo cáo khoa học: "From HOPE en I''''ESPERANCE On the Role of Computational Neurolinguistics in Cross-Language Studies " pptx

... affected. The study includes off-line picture naming which forces use of articles in all of the above contexts, as well as on-line production of these morphemes in an attempt to determine in which ... disambiguated word meaning. It is the in interaction of the results of these asynchronous processes that the process of comprehension is defined. The processes are independent of the know- ledge ... defined than through other methods, because it enables one to develop a broader perspective of the questions within an analysis of the hypothesis in the con- text of a characterization of the...
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Tài liệu Báo cáo khoa học:

Tài liệu Báo cáo khoa học: "Language Resources Factory: case study on the acquisition of Translation Memories" potx

... facilitate the acquisition of Language Resources. We build a factorythat automates the stages involved in the ac-quisition, production, updating and mainte-nance of these resources. The factory ... error in one of the inputs, Taverna will report the error message produced by the WS or proces-sor component that causes it. However, Tavernawill be able to continue processing the rest of the input ... changes considerably with WSs,as in this case only the WSP needs to have a deepknowledge of the installation and maintenance of the tool, thus allowing all the other users to benefit1from this...
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Báo cáo khoa học: A novel 2D-based approach to the discovery of candidate substrates for the metalloendopeptidase meprin pot

Báo cáo khoa học: A novel 2D-based approach to the discovery of candidate substrates for the metalloendopeptidase meprin pot

... lysine or arginineresidue. Hence, peptide fragments not featuring alysine or arginine residue in the C-terminal ends ortruncated in the N-termini by some amino acids rela-tive to the preceding ... Critchley DR (1996) Acidicphospholipids inhibit the intramolecular associationbetween the N- and C-terminal regions of vinculin,exposing actin-binding and protein kinase C phosphory-lation sites. ... media of cells with non-activatedmeprina ⁄ b (Table 1). These unique protein spots weretherefore absent in the corresponding other condition.Thus, unique spots were indicative of proteins releasedinto...
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Báo cáo khoa học: cAMP increases mitochondrial cholesterol transport through the induction of arachidonic acid release inside this organelle in Leydig cells pdf

Báo cáo khoa học: cAMP increases mitochondrial cholesterol transport through the induction of arachidonic acid release inside this organelle in Leydig cells pdf

... mitochondria. The absence of hormone ⁄ cAMP-induced steroidsynthesis when protein synthesis is inhibited can beexplained now by the inhibition in the induction of ACS4 [28] during the early response ... stimu-lation of steroidogenesis using 300 lm AA in the pres-ence of albumin. These different results can beexplained by the fact that protein binding can increase the overall concentration of fatty ... steroid synthesis, the release of AAinto the mitochondria is the first stimulator of choles-terol transport. The sustained phase of the acuteresponse will then need the induction of StAR. Wecannot...
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Báo cáo khoa học:

Báo cáo khoa học: "Estimating Upper and Lower Bounds on the Performance of Word-Sense Disambiguation Programs" docx

... the training set consists of several documents written by each of the two (or more) authors. The resulting discriminator is then tested on documents whose authorship is disputed. In the information ... for the machine; it needs all the help it can get. The conditional probabilities, Pr(wlsense), are determined during the training phase by counting the number of times that each word in the ... 100 sets of concordance lines containing one of the test words selected from a single article in Grolier's. The judges were asked to indicate if the set of concordance lines used the same...
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Báo cáo khoa học: A novel mass spectrometric approach to the analysis of hormonal peptides in extracts of mouse pancreatic islets ppt

Báo cáo khoa học: A novel mass spectrometric approach to the analysis of hormonal peptides in extracts of mouse pancreatic islets ppt

... performed in orderto get an overview of the many compounds of the pancreaticislet extract (Fig. 1a). The prominent signals in the spectrumoriginated from products of proinsulin. Two insulin variantsare ... is produced in the pancreatic a-cells and in the L-cells of the intestines. The post-translational process-ing of proglucagon is tissue-specific. In the pancreatica-cells, the main products ... 60–80% of the islets and as insulin makes up almost20% of the proteins in the b-cells, proinsulin-derivedpeptides can be expected to constitute quantitatively pre-dominant components of the extracts....
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Báo cáo khoa học: A novel splicing variant form suppresses the activity of full-length signal transducer and activator of transcription 5A pot

Báo cáo khoa học: A novel splicing variant form suppresses the activity of full-length signal transducer and activator of transcription 5A pot

... region of the variantlacked the transactivation domain and the tyrosine res-idue (Tyr694) phosphorylated by Janus protein tyro-sine kinase or other tyrosine kinases, although the DNA-binding ... splicing variant of STAT5A,STAT5A_DE18, from a cDNA library of the mousebrainstem. The variant protein was generated by aframeshift in the C-terminal region, resulting in dele-tion of the ... consists of 52 bp, similar to the case for mouse STAT5A. Therefore, we examinedwhether the splicing variant was expressed in the human brainstem. To minimize the amplification of STAT5B, the analysis...
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Báo cáo khoa học: Complement factor 5a receptor chimeras reveal the importance of lipid-facing residues in transport competence doc

Báo cáo khoa học: Complement factor 5a receptor chimeras reveal the importance of lipid-facing residues in transport competence doc

... detectable binding. To determine whether the decrease in binding affinity in the other chimeraswas the result of protein instability and misfolding orwas merely a byproduct of the localization of chimeras in ... the rest of the bundle (Fig. 3A). At the same time, the main kinks in the TM helices of rhodopsin (e.g. the functionallyimportant kink in TM6) were preserved in the 3Dmodel of C5aR. Also, the ... patterns of homo-oligomeric cross-linking for C5aR and AT1R-YFP. Because the rate of cross-linking depends on the proximity of the sidegroups, the flexibility of the structures containing the cysteine...
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Báo cáo khoa học: An internal ribosome entry site mediates the initiation of soluble guanylyl cyclase b2 mRNA translation potx

Báo cáo khoa học: An internal ribosome entry site mediates the initiation of soluble guanylyl cyclase b2 mRNA translation potx

... cells. The insertion of the sense-orientedsGC b25¢-UTR in the intercistronic position increased the translation of the downstream cistron 6.3-fold over the control (pSL3) and two- fold over the ... YesaDegree of agreement with the Kozac consensus sequence for the initiation of protein translation.bNumber of amino acids encodingfor the upstream ORF (uORF) of the sGC b25¢-UTR.cWhether thisATG ... Y-structurecharacteristic of the cellular IRES. The dotsdenote the position of the uAUG in the sec-ondary structures. The folding energy (DG)appears below each structure.Table 1. Characteristics of the initiation...
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