... to otherproteins of this class, such as the DNA-binding domain of the Mu repressor [21]. Third, the backbone atoms of the region comprising the ÔwingÕ b-sheet (residues 2–4, 35–36and 41–44 of ... in the immediate vicinity of residue 28 (Fig. 3B),indicating that the overall structure of Xis_wt is notaffected by the substitution. The DSC study revealed that the stabilities of the two proteins ... between the two a-helices),these structures can be superposed with a backbone RMSD of 0.71 A˚. The statistics of the final structure calculation aresummarized in Table 2. The global structure of...