Báo cáo khoa học: Betulinic acid-mediated inhibitory effect on hepatitis B virus by suppression of manganese superoxide dismutase expression pot

... isomeriza-tion of the Cys-Pro amide bonds in the Cys6-Pro-Cys-Pro(6–9) motif [17]. Only one configuration is detected by 113Cd(II)-NMR, whereas the other is broadenedbeyond detection by fast ... oxidatively unstable under aerobic conditions asa result of the formation of disulfide bridges [2]. Sec-ond, in contrast to the high thermodynamic stability,the binding is kinetically labile, allowing ... in metal-lothionein-3, in comparison to those in metallothionein-1 and metallothion-ein-2, and discusses the possible biological and functional implications.AbbreviationsAb, b- amyloid; AD,...

... thisregard, GIF has been demonstrated to not only preventAb aggregation, but also block the generation of ROS by Ab-Cu(II) [27,38]. Therefore, the ability of GIF toredox-silence metal ions and directly ... 2010)doi:10.1111/j.1742-4658.2010.07718.xNeuronal growth -inhibitory < /b> factor, later renamed metallothionein-3, is one of four members of the mammalian metallothionein family. Metallothione-ins are a family of ubiquitous, low-molecular-weight, ... function of neuronal growth-inhibi-tory factor within the brain, particularly in response to brain injury orduring neurodegenerative disease progression.AbbreviationsAD, Alzheimer’s disease; Ab,...