... specificallyexpressed in the central nervous system, retina, anddeveloping heart [6]. AP-2e expression has beendetected in the developing olfactory bulb, neural tis-sue, especially the midbrain and hindbrain ... AP-2e. The proline-rich and glutamine-rich N-terminus, which is important fortransactivation, is shown in yellow, and contains the PY-motif (green). The helix–span–helix domain at the C-terminus ... tried to link the expression of AP-2a in thesetissues to upstream signaling pathways. They assessed the organization of a cis-regulatory region within the fifth intron specific for directing AP-2a...