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Lean Manufacturing and the Environment: Research on Advanced Manufacturing Systems and the Environment and Recommendations for Leveraging Better Environmental Performance doc

Lean Manufacturing and the Environment: Research on Advanced Manufacturing Systems and the Environment and Recommendations for Leveraging Better Environmental Performance doc

Lean Manufacturing and the Environment: Research on Advanced Manufacturing Systems and the Environment and Recommendations for Leveraging Better Environmental Performance doc

... Manufacturing and the Environment: Research on Advanced Manufacturing Systems and the Environment and Recommendations for Leveraging Better Environmental Performance Lean Manufacturing and the Environment ... between lean implementation and organizational environmental performance. Establishing the Link Between Lean and Environmental Improvement Research for this report indicates that environmental performance ... Section IIprovides background information on lean manufacturing, section III documents four keyobservations on the relationship between lean manufacturing and environmental management, and section...
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White Papers on Advanced Manufacturing Questions  pptx

White Papers on Advanced Manufacturing Questions  pptx

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DRAFTWorkingPapersVersion040510a systems approachthatinvolvesfundingofmultipleactivitiesfrombasic research toprototypedevelopment,inanintegratedfashionisbest.DOE’sARPA‐Eprogramisonesuchprogramthathas the flexibilitytosponsorR&Dthatspansmultiplestages,frombasic research tocommercialization, and inareasthatareotherwisetoocross‐cuttingormulti‐disciplinarytofitinto the currentS&Tfundingsystem.123456789101112131415161718192021222324252627282930313233343536373839404142Createregulations and standardsettingin the areaof advanced manufacturing isanotherappropriaterole for S&Torientedagencies.ExpertsatNISTstatethatwhilehundredsofstandardsexist for ICs,almostnonedone for MEMs and othertechnologiesrelevant for advanced manufacturing. MEMS and evolvingnanotechnologyproductstendtobespecialized,customproducts; and lackofstandardscankeepcosts for newapplicationshigh, and hurtU.S.competitivenessbothindomestic and internationalmarkets(NISTMEL).16Depending on howtheyarestructured,regulations and standardsmayaddtocostofproduction,butcanalsospurinnovation.Thereareseveralexamplesin the environment domainwhereregulationstriggered the discovery and introductionofcleanertechnologies and environmental improvements.Build the physicalinfrastructure.AsGregTasseynotes,“whileproductscommercializedbased on newtechnologiesareprivategoods, the underlyingtechnologyplatforms(“generictechnologies”) and supporting“infratechnologies”arederivedfromacombinationofpublic and privateassets.”17Thisobservationisimportant for tworeasons.First,thatinfrastructureis the foundationthatcommercializedtechnologiesarebuiltupon and enablestheirdesign,development, and production, and, second,that the governmentcan and shouldplayaroleinfosteringearlyinvestmentinunder‐supported manufacturing infrastructureR&D,supplychainintegration, manufacturing systems integration, and technologymaturitylifecyclemanagement.Emergingfirmsthatlackdesignsupport,tools,matureprocesses, and technical and businessknow‐howmustdemonstratesomeplanorabilitytodeveloptheseinordertoattract the requisiteinvestmentcapitaltogetoff the ground.Existingfirmsmustconstantlyrefine and renew the technologyplatform and manufacturing processesthattheyemployinordertokeepupwithcompetitors,letalonecapturecompetitiveadvantage.Therefore, manufacturing infrastructureinnovationisseenasessentialtobothnew and existingfirms and wouldbenefitfromagovernmentcommitmenttoprovidingaccesstoworld‐bestR&D,processes, and technologies.Skill‐Building for Advanced Manufacturing Akeyfactorinrespondingquicklytocustomerneeds and developingnewprocesses and productsmorerapidly(twoimportantattributesof advanced manufacturing) isaworkforcethatisready for thesechallenges.Severalexperts,especiallyfrom the manufacturing industry,lamented the lackofappropriatelytrainedworkersfromU.S.institutions.Thisdearth(amongotherreasonstobesure)leadsthemtomanufactureelsewhere,especiallyAsia.Whenaskedifhiscompanywasbeingheldbackbyweakscience and matheducationinAmerica’sK‐12schools,PaulOtellini, the CEOofIntelcommented,“Asacitizen,Ihateit.Asaglobalemployer,Ihave the luxuryofhiring the bestengineersanywhere on earth.IfIcan’tgetthemoutofMIT,I’llgetthemoutofTsinghua.”Expertswithwhomwespokeindicatedthattoaid the UnitedStatesingrowingits advanced manufacturing economy and toovercometechnologicalchallenges,workersneedtobe better and moredifferentlyeducated. For example,inarecentreport,JamesDuderstadtof the UniversityofMichiganproposedthatundergraduateengineeringshouldbereconfiguredasanacademicdiscipline,similartootherliberalartsdisciplinesin the sciences,arts, and humanities,allowingstudentstobenefitfrom the broadereducationalopportunities for alifetimeoffurtherlearningratherthanprofessionalpractice.Simultaneously,engineering(or,perhapsmorebroadly,technology)shouldbeincludedin the liberalartscanonundergirdingatwenty‐first–centuryundergraduateeducation for allstudents.18 The governmentmayneedtoconsiderarangeofnewideassuchasthistorevampeducation for manufacturing relatedjobs.16NISTMELhomepagehttp://www.nist.gov/mel/,accessedJanuary29,2010.17GregTassey,“Rationales and mechanisms for revitalizingUS manufacturing R&Dstrategies,”op.cit.18JamesDuderstadt,“Engineering for aChangingWorld:ARoadmapto the FutureofEngineeringPractice, Research and Education,” The MillenniumProject,UniversityofMichigan,2008. ... DRAFTWorkingPapersVersion040510123456789101112131415161718192021222324252627282930313233343536373839404142434445464748 The industrysees the waytoovercomethiscost and complexityhurdleisthroughphotonicintegration.Assuch,threeclassesofdevicesrepresent the integrationin the photonicsworld. The planarlightwavecircuit(PLC)consistsonlyofpassivedevicesfabricatedfromtransparentmaterialsusingplanartechnology.Itisessentiallyopticalwiring and canperformsomesignalprocessingbutdoesnotalter the signal.TypicallyPLCmaterialsaresilica on silicon,polymers, and silicon on isolator(SOI). The industryhasusedthistechnologywidely for the last10years. The photonicintegratedcircuit(PIC)is the sameasaPLCbutalsoincludes on chipgeneration,modulation,alteration, and detection.Ithasbothpassive and activephotonicdevices(InPorGaAs‐based) and transparent and opaquesemiconductormaterialswithdifferentbandstructures and doping.Semiconductorwaferprocessingtechnologiesfabricate the opticalwaveguidedevices.PICscanbemonolithic,whereallof the devicesresideinonedie,orhybrid,wherecertaindevicesarephysicallyattachedtogetherontoacommonplatformtofunctionasoneunit.Thistechnologyrepresents the currentstate‐of the art, and whereindustryR&Disfocused. The optoelectronicintegratedcircuit(OEIC)is the sameasaPICbutincludes on chipelectronicstodrive the activeelements and provideelectricaloutputs.Itconsistsofphotonic and electronicdevicescombinedontoonechip and fabricatedusingsemiconductorprocessingtechnologies.Thisfuturetechnologyisone the industryhopestoachieve.Becauseof the largeexistinginfrastructure,siliconwouldbe the idealcandidate for photonicintegration.Althoughresearchershavefabricatedmostof the requiredactive and passiveopticalfunctionsinsilicon(Si), the fundamentalchallengehasbeenthatsilicondoesnotsupportalaser,anessentialcomponentin the opticalworld.Academic and industrialresearchershavedevisedcleverapproachestomitigatethisshortcomingofsilicon. For the mostpart,theyhaverelied on the indiumphosphide(InP)materialssystem for the laser. The problemwithInPistwofold—immatureproduction environment and concomitantly the lackofasharedcommonproductionapproach.First, the material and fabricationinfrastructureisimmature.TypicalwafersizesofInPare3inches,withleadingedgeat6inches.Siliconfabrication, on the otherhand,typicallyuses8‐or12‐inchwafers.Six‐inchtechnology for Siismanygenerationsold.Because the market for InPdevicesisrelativelysmall, the toolinfrastructurehasnotbenefitedfromahighlevelofinvestment.Second,InPdeviceshaveevolvedina manufacturing environment where the intellectualpropertyisembeddedin the process,ratherthan the design.Asaresult,onecannottakeadevicefabricatedinonefacility and replicateitusing the processesofanotherfabricationfacility(fab).Again,inthisrespectphotonicintegrationisat the levelofmaturityofsiliconin the 1960s,beforeCMOSbecame the technologyofchoice.Notwithstanding the difficultiesofmonolithicintegration on the InPplatform,somecompanies,suchasJDSU and Infinera,havesuccessfullybroughtproductsbased on monolithicInPintegrationtomarket.Oclerobelievesitiswell‐positioned for thismarketsegmentbecauseofitsInPfabinCaswellUK. The secondapproachtoPICsistointegrateasmanypassive and activecomponents on asiliconsubstrateaspossible, and thenattach and couplecriticalnon‐Sicomponentsto the platform.Oneof the advantagesofSiasaplatformisthatSiO2makes for anexcellentwaveguidematerial, and the processescanbefullycompatiblewith the existingCMOSinfrastructure. The challengeisin the mismatchof the thermalconductivitiesofInP and Si.Astemperaturechanges, the componentsmayshiftslightly,impacting the alignmentof the opticalpath.CompaniesthatfollowthisapproachincludeKotura,Luxtera, and NeoPhotonics.Potentialroadblocksaheadincludedensitylimits,both on and offchip.With the massiveamountofwirebondingrequired for theseintegratedphotonicdevices, and withall the wiresrunning10or40GHzsignalsthoughthem,theyactlikeaphaseantenna,bringingupseriousissuesofelectromagneticinterference.AnotherkeyimpedimenttoPICdevelopmentis the lackofaneconomicallyviablefoundrybase. The economicrealityisthatmanyIII‐Vfoundriesarestrugglingwithexcesscapacity and no“killerapplication”insightthatwoulddrivevolume.Companiestrytolockinwhatlittlecustomerbasetheyhavethroughproprietaryprocessesthatarenotportablefromfoundrytofoundry. On the technicalside, the lackofarobustmarket,haslimited the developmentofcomprehensivemodelingsoftware and otherinfrastructureelements.Researchersinterestedinbuildingphotonicintegratedcircuitshaveto ... DRAFTWorkingPapersVersion040510MassCustomization12345678910111213141516171819202122232425262728293031323334Oneof the definitionsof advanced manufacturing references the need for new manufacturing platformstobeflexibletorespondtocustomerdemands.Anemerging advanced manufacturing conceptsuggestedindiscussionswithexpertsis the abilitytoachievecost‐effective“masscustomization”ofaproduct.Throughadvancesincomplexproductrealization and single‐unit manufacturing, asdescribedpreviously,masscustomizationisbecomingamoreplausiblereality. Advanced manufacturing techniques,suchassolidfree‐formfabrication(oftencalled“additive manufacturing ) and laserprocessing,cancreatecomplex,customproducts and replacementpartsthatarerequiredtobeproducedquicklyinlowvolumes.5Suchadvancesin manufacturing couldleadtonewwaysofapproachingpersonalizedmedicine and biomanufacturingofpharmaceuticals.Somedefinepersonalizedmedicineas“aformofmedicinethatusesinformationaboutaperson’sgenes,proteins, and environment toprevent,diagnose, and treatdisease.”6Givenlimitations and reducedefficacyofconventionalmedicinesacrossbroadpatientpopulations,manyresearchersarelookingtowardspersonalizedhealthcarestrategies and cell‐basedtherapiesto better targetdiseases.However, manufacturing technologies for targetedtherapiesthatmeet the regulatory and economicrequirements for successfulcommercializationarestillinembryonicstages.Anotherexampleofmasscustomizationthatemergedfromdiscussionswithindustryexpertsis the manufacturing ofcustomizableprescriptioneyelenseswithuniquefeatures. The technology,developedbyLuxottica,allows for specialfeaturessuchascoatings and progressivelensestobemademorepreciselythroughnewlayeringtechnologies.Advancesin manufacturing processestocreatedesktopmachineshaveenabled the companytoautomatelens manufacturing for improvedqualityatalowercost.OpenInnovation Manufacturing Anotheremergingconceptleverages the powerofcollectiveintelligence and informationtechnologytocollectnewdesign and manufacturing strategies for productdevelopment.ArecentarticledescribesaBoston‐basedCompany,LocalMotorsInc.,as the firstopen‐sourceautomotivecompany.7LocalMotorsaimstobuildanoff‐road,butstreet‐legal,vehicletobereleasedinJune2010.ThroughaCreativeCommonslicense,8notonlydesignideasbutalsodevelopment and manufacturing solutions(mostofwhichwereoff the shelfcomponents)weresolicitedfrom the public.Throughwell‐managedcommunityinputaswellastechnologiessuchas3‐Ddesignsoftware and photorealisticrenderingtechnology,enthusiasts and LocalMotorsemployeesworkedtogethertodesign and buildacarthat,accordingto the article,“putsDetroittoshame.”Network‐Centric Manufacturing Arecentreport,Rationales and Mechanisms for RevitalizingU.S.R&D Manufacturing Strategies,arguesthatamajorrequirement for competitivenessin manufacturing isagreateruseofinformationtechnologytomoreeffectivelyintegrateallbusinessoperationsin manufacturing supplychains.Onemethodofachievingthisgoalisthroughnetwork‐Centric manufacturing (NCM),definedas:95GregTassey,“Rationales and mechanisms for revitalizingUS manufacturing R&Dstrategies,”JournalofTechnologyTransfer,publishedonline29Jan2010,availableathttp://www.springerlink.com/content/e70574777627wmg4/fulltext.pdf.6SeeNationalCancerInstitute,“DefinitionofTerms,”availableathttp://www.cancer.gov/templates/db_alpha.aspx?CdrID=561717.7ChrisAnderson,“In the NextIndustrialRevolution,AtomsAre the NewBits,”WiredMagazine,January25,2010.8CreativeCommonsisanonprofitorganizationthatworkstoincrease the amountofcreativity(cultural,educational, and scientificcontent)in“the...
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INTERNATIONAL AGENCY FOR RESEARCH ON CANCER WORLD HEALTH ORGANIZATION: Vitamin D and Cancer pptx

INTERNATIONAL AGENCY FOR RESEARCH ON CANCER WORLD HEALTH ORGANIZATION: Vitamin D and Cancer pptx

... pmol/L d stands for deci; m stands for milli; µ stands for micro; n stands for nano; p stands for pico; and f stands for femto Abbreviations for measure of risk in epidemiological and clinical ... obtaining better information on dose-response relationships, the role of the pattern of exposure for melanoma and BCC and the role of exposure at various times in life. The data on ambient ... widespread in the Netherlands and in Nordic countries, and the changes recently observed on the anatomical distribution of BCC and melanoma in these countries supports the hypothesis that sunbed...
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Digital Sound Recorder: A case study on designing embedded systems using the UML notation.

Digital Sound Recorder: A case study on designing embedded systems using the UML notation.

... converter The interface between the microphone and the processorDigital to analogue converter The interface between the processor and the microphoneScreen controllerGenerates the image on the ... manufacturer. These requirements are described in the secondsection of this document. The third section discusses the object model of the system and presents the main classdiagram. The fourth section continues ... it5Set the clock time The user can set the clock time and adjust it to the current time zone.Watch the time The system constantly shows the current time and date on the display. The user justlooks...
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research on gas - sensing properties of lead sulfide-based sensor for detection

research on gas - sensing properties of lead sulfide-based sensor for detection

... of the layer at this state. There is a threshold value of concentrationbetween the first and second stage. Only when the gas concen-tration exceeds the threshold value will the second adsorptionappear. ... inconcentration until the NO2gas concentration exceeded a certainvalue, as it can be seen in Fig. 4. The relation curves between the response and gases concentration show a saturation point and ... explained. One of possible reasons is that sulfurion concentration, chemical reaction rate and temperature influ-ence the surface area and the activation absorption center (position and quantity)...
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ESMA''''s technical advice to the European Commission on possible implementing measures of the Alternative Investment Fund Managers Directive doc

ESMA''''s technical advice to the European Commission on possible implementing measures of the Alternative Investment Fund Managers Directive doc

... accessible for future reference for a period of time adequate for the purposes of the information and which allows the unchanged reproduction of the information stored. ‘Group’, in relation to ... function’ means the relevant persons or body or bodies responsible for the supervision of its senior management and for the assessment and periodical review of the adequacy and effectiveness of the ... additional own funds and professional indemnity insurance, on one side, and of a cap for the additional own funds required under article 9(7) of the AIFMD, on the other side. Furthermore, the request...
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Báo cáo khoa học: Effects of the antioxidant PycnogenolÒ on cellular redox systems in U1285 human lung carcinoma cells docx

Báo cáo khoa học: Effects of the antioxidant PycnogenolÒ on cellular redox systems in U1285 human lung carcinoma cells docx

... stress in the form of H2O2. The cells werefirst incubated with PycnogenolÒ for 48 h, followed byH2O2treatment at a concentration of 0.1 mm and incubation for an additional 48 h. Then the ... comparedto the control as shown in Fig. 4A. However, the increase was reversible for TrxR after addition of25 lgÆmL)1PycnogenolÒ, declining to the basal level.GPx, on the other hand, barely responded ... decreased inparallel with the duration of incubation for both treated and non-treated cells, reflecting varying expression at the various stages of the cell cycle. The presence of Pyc-nogenolÒ(25...
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RESEARCH ON THE CHANGE OF 2-AP AND OTHER VOLATILE COMPOUNDS IN PROCESSING BUN FROM RICE

RESEARCH ON THE CHANGE OF 2-AP AND OTHER VOLATILE COMPOUNDS IN PROCESSING BUN FROM RICE

... 250C. The injection was performed in splitless mode first (5 min for SPME and 2 min for SDE), then in split mode to the end of the cycle (38.5 min for SPME and 70 min for SDE). After warming the ... used for the GC/MS analysis. The transfer line and the 3. RESULTS AND DISCUSSION 3.1. Extraction, identification, and quantification of 2-AP in Pandan leaf In this experiment, response ... Phuoc Hien, 2011). Based on the two methods we studied for extraction and quantitative analysis of 2-AP in the pandan leaf and used it as the standard for qualitative and quantitative analysis...
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Tài liệu The Early Detection Research Network: Investing in Translational Research on Biomarkers of Early Cancer and Cancer Risk docx

Tài liệu The Early Detection Research Network: Investing in Translational Research on Biomarkers of Early Cancer and Cancer Risk docx

... agencies—NIST, the Centers for Disease Control and Prevention, FDA, the Pacific Northwest National Laboratories of the Department of Energy and the National Aeronautics and Space Administration (NASA) ... for Cancer Screening, Diagnosis and Therapy: The State of the Science, Evaluation, Implementation and Economics (Margie Patlak and Sharyl Nass, 2006) and Cancer Biomarkers: The Promises and ... translational paradigm for the discovery and validation of biomarkers for cancer early detection and risk assessment. As noted, early performance was uneven. CEVCs, in collaboration with others...
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Tài liệu BETTER RESEARCH FOR BETTER BUSINESS: The Expert Panel on Management, Business, and Finance Research pptx

Tài liệu BETTER RESEARCH FOR BETTER BUSINESS: The Expert Panel on Management, Business, and Finance Research pptx

... targeted to research in energy, the environment, and information and communications technologies, and $37 million to the Canadian Institutes of Health Research (CIHR) for research in the health ... and design, the assembly and guidance of the research team, oversight of the conduct of the research, and the dissemination of the results to academics, practitioners, and organizations. 2 Chapter ... the use of the journal classication system developed for the U.S. National • Science Foundationa comparison against the Scopus and Web of Science classication systems the identication...
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