Báo cáo khoa học: Small peptides derived from the Lys active fragment of the mung bean trypsin inhibitor are fully active against trypsin pptx

Báo cáo khoa học: Small peptides derived from the Lys active fragment of the mung bean trypsin inhibitor are fully active against trypsin pptx

Báo cáo khoa học: Small peptides derived from the Lys active fragment of the mung bean trypsin inhibitor are fully active against trypsin pptx

... Small peptides derived from the Lys active fragment of the mung bean trypsin inhibitor are fully active against trypsin Rui-Feng Qi 1 , Zhi-Xue Liu 2 , ... studied Bowman–Birk protease inhibitors. A modified peptide, Lys3 3GP, with 33 residues derived from the long chain of the Lys active fragment of mung bean trypsin inhibitor, w...
Ngày tải lên : 15/03/2014, 09:20
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Báo cáo khoa học: A peptide derived from cyclin-dependent kinase activator (p35) specifically inhibits Cdk5 activity and phosphorylation of tau protein in transfected cells pdf

Báo cáo khoa học: A peptide derived from cyclin-dependent kinase activator (p35) specifically inhibits Cdk5 activity and phosphorylation of tau protein in transfected cells pdf

... constitute the smallest fragment (p16) of p35 that fully activates Cdk5 [20] (Fig 1A). That study found that further truncation of p16, removing either the N-terminal 11 residues (part of the p35 ... appears to be a consequence of the rigidity of the cyclin box structure of the activator compared to the relatively more flexible T-loop. Judging from the crystal...
Ngày tải lên : 23/03/2014, 21:21
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Tài liệu Báo cáo khoa học: A facile method for expression and purification of the Alzheimer’s disease-associated amyloid b-peptide pdf

Tài liệu Báo cáo khoa học: A facile method for expression and purification of the Alzheimer’s disease-associated amyloid b-peptide pdf

... A common drawback of such approaches is the cost of the affinity resins used to isolate the fusion protein and the proteases required to liberate the protein of interest from the fusion protein. ... concentrated manner at the top of the column, or, if bound to the resin prior to packing the column, the salt gradient concen- trates the peptide on its way out o...
Ngày tải lên : 18/02/2014, 13:20
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Tài liệu Báo cáo khoa học: Verprolin function in endocytosis and actin organization Roles of the Las17p (yeast WASP)-binding domain and a novel C-terminal actin-binding domain doc

Tài liệu Báo cáo khoa học: Verprolin function in endocytosis and actin organization Roles of the Las17p (yeast WASP)-binding domain and a novel C-terminal actin-binding domain doc

... when the CABS charged cluster or the LBD are mutated are not simply due to decreased protein expression or stability. Neither mutation of the CABS VH2-C domain charged cluster nor deletion of the LBD ... pro- teins, but we expect that the relative expression level of the tagged proteins is indicative of that of the equival- ent untagged proteins. To assess the fu...
Ngày tải lên : 18/02/2014, 16:20
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Tài liệu Báo cáo khoa học: Multiple promoters regulate tissue-specific alternative splicing of the human kallikrein gene, KLK11⁄hippostasin ppt

Tài liệu Báo cáo khoa học: Multiple promoters regulate tissue-specific alternative splicing of the human kallikrein gene, KLK11⁄hippostasin ppt

... antibody raised against KLK11 was the same size as that of the translational product by isoform 2 mRNA (Fig. 4B). The product by isoform 1 mRNA was smaller than the isoform 2 product. The multiple bands ... isoforms 1 and 2 are detected in the organ. All of these nucleotide sequences were identical to the genomic sequence of the human KLK11 gene (GenBank accession nu...
Ngày tải lên : 19/02/2014, 06:20
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Tài liệu Báo cáo khoa học: Endogenous expression and protein kinase A-dependent phosphorylation of the guanine nucleotide exchange factor Ras-GRF1 in human embryonic kidney 293 cells pptx

Tài liệu Báo cáo khoa học: Endogenous expression and protein kinase A-dependent phosphorylation of the guanine nucleotide exchange factor Ras-GRF1 in human embryonic kidney 293 cells pptx

... mediates activation of Ras subsequent to the stimulation of G i - and G q - coupled receptors [8,9]. The main mechanism for the activation of Ras- GRF1 is the binding of Ca 2+ ⁄ CaM to the N-terminal IQ ... identified [17,19]. The smaller iso- forms correspond to N-terminal deletions of the full- length 140 kDa protein. The physiological role of the guanine nucleo...
Ngày tải lên : 19/02/2014, 18:20
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Tài liệu Báo cáo khoa học: "Exploiting Readymades in Linguistic Creativity: A System Demonstration of the Jigsaw Bard" docx

Tài liệu Báo cáo khoa học: "Exploiting Readymades in Linguistic Creativity: A System Demonstration of the Jigsaw Bard" docx

... the scale of the Bard’s genera- tivity, and the quality of its insights. 5 Empirical Evaluation The vastness of the web, captured in the large- scale sample that is the Google ngrams, means the Jigsaw ... properties are indeed acquired from the Web for our vocabulary of stereotypes (this point relates to the aptness of the similes sug- gested by the Bard)...
Ngày tải lên : 20/02/2014, 05:20
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Tài liệu Báo cáo khoa học: Cell surface heparan sulfate proteoglycans Target and partners of the basic ®broblast growth factor in rat Sertoli cells pptx

Tài liệu Báo cáo khoa học: Cell surface heparan sulfate proteoglycans Target and partners of the basic ®broblast growth factor in rat Sertoli cells pptx

... coreceptors, are m ainly regulated at the transcriptional level. This report s hows that the b FGF r egulation of their expression speci®cally depends on the nature of HSPG and of the Sertoli ... (HSPG) on the cell surface [11]. Oligosaccharidic sequences of HS chains are de®ned for the bFGF binding and for the recognition of the speci®c bFGF receptor, leading to...
Ngày tải lên : 21/02/2014, 03:20
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Báo cáo khoa học: Nup358, a nucleoporin, functions as a key determinant of the nuclear pore complex structure remodeling during skeletal myogenesis docx

Báo cáo khoa học: Nup358, a nucleoporin, functions as a key determinant of the nuclear pore complex structure remodeling during skeletal myogenesis docx

... regulates the formation of transport complexes. GTP hydrolysis by Ran in the cytoplasm drives disso- ciation of the export cargo from the export complex, whereas RanGTP promotes disassembly of the ... regulates the move- ment of molecules into and out of the nucleus and is necessary for the survival of eukaryotic cells. The pas- sage of molecules such as RNA,...
Ngày tải lên : 06/03/2014, 01:20
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Báo cáo khoa học: Relation between domain evolution, specificity, and taxonomy of the a-amylase family members containing a C-terminal starch-binding domain pot

Báo cáo khoa học: Relation between domain evolution, specificity, and taxonomy of the a-amylase family members containing a C-terminal starch-binding domain pot

... linkers The initial analysis of 40 amino acid sequences of GH 13 members having the ÔclassicalÕ SBD (Table 1) revealed that, in fact, there are two groups of these enzymes, which are the five-domain ... agreement with the complete-sequence tree (Fig. 3A). In the group of CGTases produced by the genera Bacillus and Thermo- anaerobacter (the large compact clusters in th...
Ngày tải lên : 08/03/2014, 08:20
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