... Department of Medical Biophysics, University of Toronto, Canada4 Department of Laboratory Medicine and Pathology, University of Toronto, Canada5 Department of Biochemistry, University of Toronto, ... levels after CsA treatment. Gb3was undetected in wild-type liver, and the levels of Gb3(but not gangliosides) in Fabry mouse liver were significantly depleted byCsA treatment. VT1 liver histochemistry ... and 4, lipidextract of wild-type liver; (F, G) lane 1, GSL standards; lanes 2 and 4, lipid extracts of control Fabry liver; lanes 3, 5, lipid extracts of CsA-treated Fabry liver. Gb3is only...