Báo cáo khoa học: a-Fetoprotein positively regulates cytochrome c-mediated caspase activation and apoptosome complex formation docx

Báo cáo khoa học: a-Fetoprotein positively regulates cytochrome c-mediated caspase activation and apoptosome complex formation docx

Báo cáo khoa học: a-Fetoprotein positively regulates cytochrome c-mediated caspase activation and apoptosome complex formation docx

... AFP stimulates formation of the Apaf-1 apoptosome complex, enhances recruitment and activation of procaspase 3 in the complex, and stimulates release of active caspase 3 and 9 from the apoptosome. ... the complexes. Fig. 7. AFP positively regulates formation of Apaf-1 apoptosome in cell-free extracts and promotes caspase activation and release of caspase 3...
Ngày tải lên : 08/03/2014, 08:20
  • 12
  • 401
  • 0
Tài liệu Báo cáo khoa học: Collagen I regulates matrix metalloproteinase-2 activation in osteosarcoma cells independent of S100A4 pdf

Tài liệu Báo cáo khoa học: Collagen I regulates matrix metalloproteinase-2 activation in osteosarcoma cells independent of S100A4 pdf

... in decreased proMMP-2 activation and reduced MT1-MMP expression A decrease in the total amount of MMP-2 (72, 64 and 62 kDa bands), as well as in the active MMP-2 forms (64 and 62 kDa bands), was observed ... expression pattern and activation mechanisms. The best-described activation mechanism for MMP-2 is the two-step cell-surface activation in which proMMP-2 is activated in a...
Ngày tải lên : 18/02/2014, 11:20
  • 12
  • 572
  • 0
Tài liệu Báo cáo khoa học: Oxygen tension regulates the expression of a group of procollagen hydroxylases docx

Tài liệu Báo cáo khoa học: Oxygen tension regulates the expression of a group of procollagen hydroxylases docx

... hypoxia (0.5% oxygen) and deferoxamine (100 lmolÆL )1 ) clearly induced P4ha1 (four- and sevenfold) and P4ha2 mRNA (seven- and fourfold) and to a lesser extent also PDI mRNA (two- and 1.5-fold), whilst ... chelation and cobalt with those reported by Tanaka and coworkers for cultured astrocytes [15]. Our findings thus on the one hand fully support these previous findings and on...
Ngày tải lên : 20/02/2014, 02:21
  • 8
  • 434
  • 0
Báo cáo khoa học: Human anionic trypsinogen Properties of autocatalytic activation and degradation and implications in pancreatic diseases potx

Báo cáo khoa học: Human anionic trypsinogen Properties of autocatalytic activation and degradation and implications in pancreatic diseases potx

... l M Ca 2+ (A) and pH 5.0 (B and C). Autoactivation experiments were carried out asin Fig. 9A (A) and 10(B and C). Samples (2 l M total zymogen in 100 lL) were trichloroacetic acid-precipitated and analyzed ... trypsinogen Properties of autocatalytic activation and degradation and implications in pancreatic diseases Zolta ´ n Kukor, Miklo ´ sTo ´ th* and Miklo ´ s Sahin-To ´...
Ngày tải lên : 17/03/2014, 03:20
  • 12
  • 381
  • 0
Báo cáo khoa học: "High-precision Identification of Discourse New and Unique Noun Phrases" docx

Báo cáo khoa học: "High-precision Identification of Discourse New and Unique Noun Phrases" docx

... the literature. R. Vieira and M. Poesio use hand-crafted heuris- tics, encoding syntactic information. For exam- ple, the noun phrase “the inequities of the current land-ownership system” is classified ... discourse and the hearer givenness.The resulting taxonomy is summarised below: brand new NPs introduce entities which are both discourse and hearer new (“a bus”), sub- class of them, b...
Ngày tải lên : 31/03/2014, 03:20
  • 7
  • 285
  • 0
Tài liệu Báo cáo khoa học: Proteolytic processing regulates pathological accumulation in dentatorubral-pallidoluysian atrophy pdf

Tài liệu Báo cáo khoa học: Proteolytic processing regulates pathological accumulation in dentatorubral-pallidoluysian atrophy pdf

... (0.2 lm and 20 lm; Roche Diagnostics), pan caspase inhibitor Z-VAD-FMK (50 lm; Peptide Institute), caspase- 1 and -4 inhibitor Z-YVAD-FMK (50 lm; Bachem, Du ¨ ben- dorf, Switzerland), caspase- 2 ... tract was cleaved by caspase- 3 in vitro and in the human brain tissues [27], and that cleavage at the caspase- 6 site in huntingtin was essential for the HD-related behavioural and...
Ngày tải lên : 15/02/2014, 01:20
  • 15
  • 590
  • 0
Tài liệu Báo cáo khoa học: Inorganic phosphate regulates the binding of cofilin to actin filaments pdf

Tài liệu Báo cáo khoa học: Inorganic phosphate regulates the binding of cofilin to actin filaments pdf

... of Chemistry and Biochemistry and the Molecular Biology Institute, University of California, USA Actin dynamics, the polymerization and depolymeriza- tion of actin filaments and formation of ordered ... of breakage and destruction of filaments upon exposure to SDS and potassium iodide (KI) [30], and the decreased tryptic susceptibility of the 60–69 loop in subdomain 2 [31]. Phos...
Ngày tải lên : 19/02/2014, 07:20
  • 9
  • 487
  • 0
Tài liệu Báo cáo khoa học: Adaptive changes in the expression of nuclear and mitochondrial encoded subunits of cytochrome c oxidase and the catalytic activity during hypoxia pptx

Tài liệu Báo cáo khoa học: Adaptive changes in the expression of nuclear and mitochondrial encoded subunits of cytochrome c oxidase and the catalytic activity during hypoxia pptx

... genes CytOX5a and CytOX5b, coding for the two isofoms Va and Vb, parallels that of genes CYC1 and CYC7, which encode iso-1 and iso-2 of yeast cytochrome c, respectively. CytOX 5a and CYC1 are ... resolved as two major complexes, which comigrated with Apo-ferritin and b-amylase. Based on the rates of migration, the slow migrating complex may be a dimmer and the faster migrati...
Ngày tải lên : 20/02/2014, 23:20
  • 9
  • 554
  • 0
Báo cáo khoa học: Heterologous synthesis of cytochrome c¢ by Escherichia coli is not dependent on the System I cytochrome c biogenesis machinery ppt

Báo cáo khoa học: Heterologous synthesis of cytochrome c¢ by Escherichia coli is not dependent on the System I cytochrome c biogenesis machinery ppt

... Allochromatium vinosum cytochrome c¢; Ccm, cytochrome c maturation; Dsb, disulfide bond formation; EC b 562 , Escherichia coli cytochrome b 562 ; PHCP, Hydrogenophilus thermoluteolus cytochrome c¢;PHc 552 , ... cyto- chrome c¢ (PHCP) and H. thermoluteolus cytochrome c 552 (PH c 552 ) genes are indicated as c¢ and c 552 , respectively. The arrow and arrowhead indicate the posit...
Ngày tải lên : 06/03/2014, 00:20
  • 8
  • 606
  • 0
Báo cáo khoa học: NF-jB regulates the transcription of protein tyrosine kinase Tec pdf

Báo cáo khoa học: NF-jB regulates the transcription of protein tyrosine kinase Tec pdf

... inactivation of Btk and Tec genes in mice cause a severe phenotype resembling XLA. Tec is involved in the regula- tion of both B and T lymphocytes, fine-tuning of TCR ⁄ BCR signaling, and also activation ... T-cell line Jurkat and in two liver cell lines, HepG2 and Huh7 (Fig. 5C, left part, and data not shown). The proteasome and NF-jB inhibitors repress transcription from the...
Ngày tải lên : 07/03/2014, 00:20
  • 11
  • 450
  • 0

Xem thêm

Từ khóa: