Báo cáo khoa học: Structural diversity in lipopolysaccharide expression in nontypeable Haemophilus inﬂuenzae Identiﬁcation of L-glycero -D-manno-heptose in the outer-core region in three clinical isolates potx

Tài liệu Báo cáo khoa học: What makes biochemical networks tick? A graphical tool for the identiﬁcation of oscillophores ppt

... cycles in such a combinationdo not touch each other). The value (the sign) of a cycle is the product of the values (the signs) of its steps. The sign o f the magnitude of a Ôminus combined autoinfluence ... concentrations of itsspecies. Therewith the c oefficient of o rder p of the characteristic equation equals the sum of all simplestcombined Ôminus autoinfluence paths of order pÕ in the network. ... cause instability. Then only the negative autoinflu-ence path of Eqn (16) remains, which then cancels the positive autoinfluence of Eqn (17). Revolving around the cycle then does not lead to an increase...

Báo cáo khoa học: Structural and functional roles for b-strand 7 in the a-crystallin domain of p26, a polydisperse small heat shock protein from Artemia franciscana pdf

... the remaining b-strands, with the exception of strand 6, are arranged in two antiparallelbeta sheets within the a-crystallin domain. The inter-face between monomers of a dimer involves interactionbetween ... directly in the dimer–dimer interface. As a result of the spatial dis-position of monomers and their b-strand elements in the a-crystallin domain, the amino acid substitutionF112R introduces ... within the a-crystallin domain, better understand the conse-quences of amino acid substitutions, and identify pro-tein regions involved in oligomer assembly. The fourmodiﬁed a-crystallin domain...

Báo cáo khoa học: Structural evidence for a constant c11 ring stoichiometry in the sodium F-ATP synthase doc

... the size of the ring isnot changed by massive overexpression of subunit c in the E. coli host cells, indicating that intrinsic fea-tures of the monomeric unit determine the number of subunits ... c10complex in the recombinant c ringpreparations suggests that the insertion of the last csubunit forms the limiting step in the assembly process of a functional oligomer.Upon closer inspection, the ... be packed into the ring. These dataare fully compatible with the recent ﬁnding that the stoichiometry of the subunit III cylinder within the ATP synthase of the green algae, C. reinhardtii,isnot...

Tài liệu Báo cáo khoa học: Structural characterization of Ca2+/CaM in complex with the phosphorylase kinase PhK5 peptide pdf

... aC-terminal extension to the protein kinase folds backon the kinase domain and interferes with the substratebinding sites. In the case of the titin and twitchinkinases, the autoinhibitory sequence ... extrinsic calmodulin (CaM). The c subunit is the catalytic subunit and the d subunit is an intrinsic mole-cule of CaM that binds to the enzyme even in the absence of Ca2+[2]. The regulation of ... hexadecameric enzyme consisting of four copies of four subunits: (abcd)4. An intrinsic calmodulin (CaM, the dsubunit) binds directly to the c protein kinase chain. The interaction site of CaM on c has...

Tài liệu Báo cáo khoa học: "Structural and Topical Dimensions in Multi-Task Patent Translation" ppt

... into a single training set. Instead of a trivial enlargement of training data by pooling,we train the pooled models on the same amount of sentences as the individual models. For in- stance, the ... 2003. Minimum error rate train-ing in statistical machine translation. In Proceed-ings of the Human Language Technology Confer-ence and the 3rd Meeting of the North AmericanChapter of the Association ... models. In Pro-ceedings of the 20th International Conference onComputational Linguistics (COLING’04), Geneva,Switzerland.828Proceedings of the 13th Conference of the European Chapter of the...

Báo cáo khoa học: Structural and functional aspects of unique type IV secretory components in the Helicobacter pylori cag-pathogenicity island potx

... this family.Finally, when crystallized in the presence of Cu(II), the protein shows the presence of the ion coordinated in a small cavity of the surface at the polar opposites of each monomer, ... [38]. In particular, SycTshares the same topology in the region including the N-terminal helix and the b-sheet element, whereas itdisplays a remarkable difference in the orientation of the a-helices ... to another dimer present in the crystal packing and partially involving it in the coordination. It is likely that the presence of Cu(II) isan artefact of the crystallization, although the possibil-ity...

Báo cáo khoa học: Structural and functional evidence for a singular repertoire of BMP receptor signal transducing proteins in the lophotrochozoan Crassostrea gigas suggests a shared ancestral BMP/activin pathway docx

... clarify the binding properties of each of these domains we generated synthetic mRNA encodingonly the C1 or C2 domains. Expression of only the C1domain resulted in the dorsalization of embryos in ... and the cysteine knot is boxed.Also boxed are the transmembrane domain, the ATP binding site, the L45 loop and the serine ⁄ threonine kinase domain. (B) The implied amino acid sequence of Cg-TGFbsfR2 ... ⁄ threonine kinase domain [22]. Anotherstriking point is the phase conservation of the intron–exon boundaries that lie either side of the exon enco-ding the extracellular domain. This lends...

BÀI BÁO CÁO KHOA HỌC TẠI BẮC KINH ATCM 2009 THE SCIENTIFIC REPORT IN BEIJING - CHINA

... 1 The number contains the end two digits are digit 1 The number contains the end three digits are digit 1 The number contains the end four digits are digit 1Answer : the number contains the ... know that the number contains the first four digits and the end four digits are digit 1Step 1 : Find the number contains the end four digits are digit 1.Solution : The number contains the end ... =5. Find the fourteenth digit after of the decimal point of We have : the digit 5 can have rounded We try the digit 5 can not have rounded We set : The second power of two sides of equation...

Tài liệu Báo cáo khoa học: How to remain nonfolded and pliable: the linkers in modular a-amylases as a case study ppt

... near the N- and C-termini of the linkers: this suggests thata mobile connection with both the catalytic domainand the binding module is required for the function of the nanomachine. Furthermore, ... covering the face of the aromatic ring [25].Alternatively, the ring may sterically disfavor extensivebending in this region, which could result in unwantedinteractions between the linker and the ... C-terminal domain. URLs of the relevantgenome databases are given in Table S1. The linkerbetween the core enzyme and its C-terminal domain wasdeﬁned as the region between the end of the usual...

Tài liệu Báo cáo khoa học: Structural and functional studies of the human phosphoribosyltransferase domain containing protein 1 docx

... N7 (Fig. 1C). The 2¢OH of the ribose is hydro-gen bonded to the main chain and the side chain of Asp142 (Fig. 1C). Both hydroxyl groups of the riboseare involved in coordinating a putative ... solutions. The ligandbound was interpreted as GMP because the N2 of the base makes a hydrogen bond to a main chain car-bonyl. Binding of a xanthine base from XMP in the same position, would lead to the ... for the quantitation of microgram quantities of proteinutilizing the principle of protein-dye binding. AnalBiochem 72, 248–254.28 Page R & Stevens RC (2004) Crystallization data min-ing in...

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