... HAH1 and either the second or the fifthsoluble domains of ATP7A (MNK2 and MNK5, respectively), in the pres-ence of copper(I). The copper-transfer properties of MNK2 and MNK5are similar, and ... An NMR study of the interaction between the humancopper(I) chaperone and the second and fifthmetal-binding domains of the Menkes proteinLucia Banci1,2, Ivano Bertini1,2, ... equilibrationconstant of the order of 5–10, with the soluble domains of ATP7A being better ligands for copper(I) thanHAH1. In other words, our data are consistent with the copper(I)-binding constant of MNK2 and...