Báo cáo khoa học: Modulation of glucocorticoid receptor-interacting protein 1 (GRIP1) transactivation and co-activation activities through its C-terminal repression and self-association domains pptx

... 563 11 21, 5–765, and AD2AD2AD2AD2 11 22 11 22 13 05 13 05 14 62 14 62 14 62 14 62AD1AD1AD2AD25 14 62 14 62AD1AD15 11 21 112 1AD1AD1AD2AD2 14 62 14 62563563AD1AD1 11 21 112 1563563AD1AD1 13 04 13 04563563[Gal4DBD; ... 10 %Input 10 %GSTInput 10 %Input 10 %GSTGST 11 22 -13 04 13 05- 1 398 1 305- 1 398 13 05 -14 62 13 05 -14 62 13 99 -14 62 13 99 -14 62GST-GRIP1GST-GRIP1GRIP1 11 22 -14 62GRIP1 11 22 -14 62 11 22 -14 62 11 22 -14 62 13 05 -14 62 13 05 -14 62GST-GRIP1GST-GRIP1 1 ... 234596 10 10 11 11 7 12 12 8HA.GRIP1563 -14 62HA.GRIP1563 -14 62HA.GRIP15-765HA.GRIP15-765HA.GRIP15 -11 21 HA.GRIP15 -11 21 HA.GRIP1563 -1 1 21 HA.GRIP1563 -1 1 21 Gal4DBD.GRIP15 -14 62Gal4DBD.GRIP15 -14 62+++++...

Tài liệu Báo cáo khoa học: Modulation of a-synuclein aggregation by dopamine in the presence of MPTP and its metabolite pptx

... ipsita@niper.ac.in(Received 28 September 2 010 , revised 24February 2 011 , accepted 7 March 2 011 )doi :10 .11 11/ j .17 42-4658.2 011 .08093.xThe neurotransmitter dopamine has been shown to inhibit ﬁbrillation of a-synuclein by ... al. 16 98 FEBS Journal 278 (2 011 ) 16 88 16 98 ª 2 011 The Authors Journal compilation ª 2 011 FEBS Modulation of a-synuclein aggregation by dopamine in thepresence of MPTP and its metabolitePrashant ... allopurinolon 1- methyl-4-phenyl -1, 2,3,6-tetrahydropyridineP. N. Jethva et al. Modulation of a-synuclein aggregationFEBS Journal 278 (2 011 ) 16 88 16 98 ª 2 011 The Authors Journal compilation ª 2 011 FEBS 16 97(MPTP)-induced...

Tài liệu Báo cáo khoa học: Modulation of F0F1-ATP synthase activity by cyclophilin D regulates matrix adenine nucleotide levels pptx

... FEBS Lett 233, 17 – 21. C. Chinopoulos et al. Effect of CYPD on mitochondrial ATP flux ratesFEBS Journal 278 (2 011 ) 11 12 11 25 ª 2 011 The Authors Journal compilation ª 2 011 FEBS 11 23 41 Hale DE & ... on mitochondrial ATP flux ratesFEBS Journal 278 (2 011 ) 11 12 11 25 ª 2 011 The Authors Journal compilation ª 2 011 FEBS 11 25 Modulation of F0F 1 -ATP synthase activity by cyclophilin Dregulates ... 0aReverse mode of operation for both ANT and F0F 1 -ATP synthase.Effect of CYPD on mitochondrial ATP flux rates C. Chinopoulos et al. 11 16 FEBS Journal 278 (2 011 ) 11 12 11 25 ª 2 011 The Authors...

Tài liệu Báo cáo khoa học: Modulation of sterol homeostasis by the Cdc42p effectors Cla4p and Ste20p in the yeast Saccharomyces cerevisiae pptx

... independentexperiments.lg of sterol per mg of protein wild-type ste20D cla4D swe1D cla4D swe1DErgosterol 15 . 21 ± 0.66 20 .1 ± 1. 67 19 .58 ± 0.57 15 .15 ± 0.98 18 .18 ± 1. 11 Zymosterol 0.62 ± 0 .14 0.84 ± 0.06 0.76 ± 0 .11 ... polarityproteins in mitotic exit. EMBO J 21 , 48 51 4862. 17 Seshan A, Bardin AJ & Amon A (2002) Control of Lte1 localization by cell polarity determinants and Cdc14. Curr Biol 12 , 2098– 211 0. 18 ... M & Dickson R (19 98) Bio-chemistry, cell biology and molecular biology of lipids of Saccharomyces cerevisiae. Yeast 14 , 14 71 15 10.33 Schneiter R, Bru¨gger B, Sandhoff R, Zellnig G, LeberA,...

Tài liệu Báo cáo khoa học: Modulation of the enzymatic efﬁciency of ferredoxin-NADP(H) reductase by the amino acid volume around the catalytic site pptx

... value)0 20 40 60 80 10 00. 01 0 .1 10 10 002340. 01 0 .1 1 10 10 00.0 0 .1 0.2 0.3 0.4 0.5kcat /Km (%)kcat /Km (%) 1 ABCDFig. 5. Catalytic efﬁciencies of wild-type and mutant FNRs plotted ... 31 ± 5L268V )25.0 31 ± 1 308 ± 15 9.97 ± 0.50 0.54 37 ± 2 31 ± 4C266AL268A )96.2 299 ± 42 3.5 ± 0.5 0. 011 ± 0.003 4.58 87 ± 6 12 0 ± 8C266L 53.2 16 ± 2 2.32 ± 0.04 0 .14 ± 0. 01 3.07 29 ± 4 18 ... 268, 14 7 15 7. 11 Arakaki AK, Ceccarelli EA & Carrillo N (19 97) Plant-type ferredoxin-NADP+reductases: a basal structuralframework and a multiplicity of functions. FASEB J 11 , 13 3 14 0.M....

Tài liệu Báo cáo khoa học: Modulation of oat arginine decarboxylase gene expression and genome organization in transgenic Trypanosoma cruzi epimastigotes docx

... Argentinas 435 (14 05),Buenos Aires, ArgentinaFax: +5 411 5238 75 01 Tel: +5 411 5238 7500E-mail: ialgranati@leloir.org.ar(Received 24 November 2005, accepted 12 December 2005)doi :10 .11 11/ j .17 42-4658.2005.05098.xWe ... putrescine, as a result of the absence of ornithine and arginine decarboxylases (ODC and ADC) [7 10 ], which catalyse the ﬁrst steps of bothpossible pathways of putrescine biosynthesis [11 ]. Inaccordance ... 9, 11 and 13 show the PCR products obtained using the primer pair T7 and RIB. Lanes 2, 4, 6, 8, 10 , 12 and 14 showthe PCR products obtained using the primer pair T7 and ADC2. Lane 15 , 1 kb DNA...

Tài liệu Báo cáo khoa học: Modulation of cyclin D1 and early growth response factor-1 gene expression in interleukin-1b-treated rat smooth muscle cells by n-6 and n-3 polyunsaturated fatty acids pdf

... action of EPA and DHA (Eur. J. Biochem. 2 71) 4465 Modulation of cyclin D1 synthesis and hyperphosphorylation of Rb by n-3 and n-6 PUFAsInduction of cyclin D1 is one of the e arliest effects of mitogenic ... -40 p lus 1 lgÆmL )1 of leupeptine, 1 lgÆmL )1 of pepstatin, 1 mMphenyl-methanesulfonyl ﬂuoride, and 1 mMEDTA]. Nuclearextracts were prepared as described above. Equal amounts of protein ... binding of the transcription factors Egr -1, as for NF-jBandEts -1, probably by reducing MAPK activity [18 ]. As NF-jB, Ets -1 and Egr -1 are substrates of MAPK [12 ,43,44], the inhibition of MAPK...

Báo cáo khoa học: Modulation of nitric oxide-mediated metal release from metallothionein by the redox state of glutathione in vitro doc

... 2004,accepted 14 April 2004)Eur. J. Biochem. 2 71, 2408–2 416 (2004) Ó FEBS 2004 doi :10 .11 11/ j .14 32 -10 33.2004.0 416 0.xBased on the preferred release of metal from theb-domain of mouse MT1, where zinc ... characterization of pure 20 lMCd5Zn2-MT2 and mixtures of MT2 + NO (1 +11 ) and MT2 + GSH + NO (1 +25 +10 ). The amount of zinc and cadmium is shown as a function of retention time and isgiven ... rather extreme NOFig. 1. Wavelength and time scans of the CD of MT2 in the presence and absence of NO and GSH/GSSG. CD spectra of 10 0 lMCd5Zn2-MT2 alone or with 1 mMGSH in 20 mMpotassium...

Báo cáo khoa học: Modulation of IMPDH2, survivin, topoisomerase I and vimentin increases sensitivity to methotrexate in HT29 human colon cancer cells docx

... cyclepLK PLK U 010 38 P53350 0.04 0.50E2F -1 E2F1 M96577 Q 010 94 0 .14 0 .16 Membrane-associated kinase Myt1 AF 014 118 O147 31 0.23 0.39Cyclin C CCNC M740 91 P24863 0.08 0.08Serine ⁄ threonine protein kinase ... Q00534 0. 01 0 .12 P53-like transcription factor P73 Y 114 16 O15350 0. 01 0.07p19INK4d; p19 protein CDKN2D U40343 P55273 0 .19 0 .12 Cytoskeleton-motility proteinsGrowth-arrest-speciﬁc protein 2 ... associated proteinsRetinoid X receptor beta; retinoic acid X receptor b RXRB M84820 P28702 0 .11 0.30WSL-S2 protein; WSL-S1 protein; WSL-1R protein TNFRSF12 Y09392 Q93038 0 .14 0 .11 Cell cyclepLK...

Báo cáo khoa học: Modulation of amyloid-b aggregation and toxicity by inosose stereoisomers pot

... metabolism and chem-ical toxicity. Chem Res Toxicol 14 , 611 –650.27 Spector R (19 78) The transport and metabolism of scyllo-inositol in the central nervous system. J Neuro-chem 31, 11 13 11 15.28 ... (nm)ThetaA5005000–500 10 00 15 005000–500 10 00 15 00–2000400020000–2000–4000–6000–8000 10 005000–500 10 00 15 00–2000–2500–3000 10 005000–500 10 00 15 00–20000–500 10 00 15 00–20000 10 0–200–300–400–5000–500 10 00 15 00–2000–2500 19 0 200 210 220 230 240 250 260 19 0 200 210 ... 240 250 260 18 0 19 0 200 210 220 230 240 250 260 19 0 200 210 220 230 240 250 260 19 0 200 210 220 230 240 250 260 19 0 200 210 220 230 240 250 260 19 0 200 210 220 230 240 250 260 19 0 200 210 220 230...

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