Báo cáo khoa học "ADIABATIC TEMPERATURE RISE AND REACTION RATE OF MASS STRUCTURE IN LOTTE CENTER HANOI PROJECT " pptx

... ADIABATIC TEMPERATURE RISE AND REACTION RATE OF MASS STRUCTURE IN LOTTE CENTER HANOI PROJECT Dr. KIM KWANG KI, Eng. HWANG IN GWAN, Eng. KIM MYOUNG GUG Lotte E&C, Lotte Center Hanoi Project ... from initial time of hardening. Especially, a volume change in surface of mass- section element is almost same by cooling from low temperature in the air while inside of volume expands by high temperature ... stress is determined by ascension rate of peak temperature, peak temperature and intensity of restraint, it can be minimized by shop drawing, material, mixture design, construct and curing control....

Tài liệu Báo cáo khoa học: Processing, catalytic activity and crystal structures of kumamolisin-As with an engineered active site pptx

... the 57-kDa protein in a total of intensities of the 57-kDa, 38-kDa and 19-kDa bands, where the intensity of the38-kDa protein band was corrected for the amounts of the added proteins with similar ... protein bandsFig. 1. Schematic representation of the structure of the precursor of kumamolisin-As, consisting of an N-terminal propeptide (whiterectangle), the linker part (gray rectangle), and ... to nondenaturingPAGE, these proteins comigrated with each other,showing a broad protein band that differed from therespective original bands and almost coincided withthe band of the 57-kDa...

Tài liệu Báo cáo khoa học: X-ray crystallographic and NMR studies of pantothenate synthetase provide insights into the mechanism of homotropic inhibition by pantoate docx

... synthetase, one of whose substrates,IMP, binds to the GTP-binding site and inhibits the reaction [37–39]. The binding of pantoate to theATP-binding site also reveals the origin of the negativecooperativity ... ATP-binding pocket. Pantoatebinding to the ATP-binding site induced large changes in structure, mainlyfor backbone and side chain atoms of residues in the ATP bindingHXGH(34–37) motif. Sequence-speciﬁc ... results of the structural studies of the panto-ate-bound form of the N-terminal domain of E. coliPS (nPS). The structure and substrate-binding interac-tions of E. coli nPS have been studied using...

Báo cáo khoa học: Alternative splicing: good and bad effects of translationally silent substitutions pdf

... to demonstrate purifyingselection at silent sites in the gene of interest and todemonstrate that such constraint is necessary to main-tain correct splicing of the gene. In fact, although we ... field for the investigation of the ele-ments involved in splicing regulation and the integra-tion of all these approaches will give us the bestchance of finally understanding the splicing mechanismitself.An ... altering the essential protein func-tion are produced. In this review we briefly describe the current under-standing in the field and discuss emerging directions in the study of thesplicing mechanism...

Báo cáo khoa học: Protein–protein interactions and selection: generation of molecule-binding proteins on the basis of tertiary structural information potx

... protein–protein interactions and selectingspeciﬁc binders to novel target proteins, and the ﬁrst and second minireviews focus on the detection of protein–protein interactions [8,9]. In this third minire-view, ... fragments and nonantibody small scaffold proteins from X-ray and NMR analyses enables the design of and screeningfor small binding proteins. The preparation of thesmall binding proteins with binding ... [ref. 30]Randomization of X residues in CDR3 loop of heavy chainHeavychainLightchainFig. 3. Combination of grafting and locallibrary approaches in CDR 3 loops of theheavy chain to select...

Báo cáo khoa học: Amino acid limitation regulates the expression of genes involved in several speciﬁc biological processes through GCN2-dependent and GCN2-independent pathways ppt

... acidsresulting from the intestinal digestion of proteins [4,5].Another example of the detection of the lack of anamino acid is metabolic adaptation to cope with epi-sodes of protein malnutrition. In ... animportant role in controlling gene expression. Usingtranscriptional proﬁling, the objective of this work wasto gain a better understanding of the amino acid con-trol of gene expression. ... of several genes, including Chop, Atf3, Cat-1 and insulin-like growth factor binding protein 1 (Igfbp1), makingit possible that amino acid availability may affect amechanism regulating transcript...

Tài liệu Báo cáo khoa học: Nucleolin/C23 mediates the antiapoptotic effect of heat shock protein 70 during oxidative stress pptx

... 1C).Increased nucleolin/C23 protein levels in Hsp70-transfected cells in response toH2O2-induced apoptosisWe next examined the expression of nucleolin ⁄ C23protein in these cells in response ... Research Program of China (2007CB512007),the National Natural Science Foundation of China(30700290) and Special Funds for PhD Training fromThe Ministry of Education of China (20060533009).References1 ... the activity of caspase-3 was analy-sed as a marker of apoptotic cells using an in vitrosubstrate-cleaving reaction. As shown in Fig. 6D,H2O2-induced apoptosis was increased in cells trans-fected...

Báo cáo khoa học: " Medication errors: a prospective cohort study of hand-written and computerised physician order entry in the intensive care unit"

... remit of the local ethics committee. Prior tointroduction of CPOE, local standards of prescribing existedspecifying the tenets of good practice, including the avoid-ance of the use of abbreviations.An ... are the leadingtype of medical error [3]. Previously, in a setting that includedgeneral wards and ICUs, a similar type of CPOE was associ-ated with a halving of the rate of non-intercepted ... without decision support, in sev-eral ways. We compare the rates and types of MEs and thepotential outcome of intercepted and non-intercepted errors.Materials and methods In April 2002, University...

Tài liệu Báo cáo khoa học: Hypothalamic malonyl-CoA and CPT1c in the treatment of obesity pptx

... maintaining a lower foodintake. This is accompanied by a suppression in energyexpenditure. These data suggest that CPT1c canintegrate carbohydrate and lipid nutrient sensing in thebrain and ... promoting an increase in proopiomelanocortin and cocaine and amphetamineregulated transcript. Taken together, these ﬁndingsprovide a compelling argument for the role for malo-nyl-CoA in regulating ... changes in feedingbehavior and energy expenditure. Thus, insulin, leptin and ghrelin, as well as other hormones ⁄ cytokines,interact with their cognate receptors on neurons withinthe CNS that project...

Tài liệu Báo cáo khoa học: Activation loop 3 and the 170 loop interact in the active conformation of coagulation factor VIIa pdf

... allowsvisualization of the modiﬁcation using SDS–PAGE.The rate of carbamylation of the N-terminal aminogroup [Ile153(16)] of the protease domain in G372A-Fig. 2. PABA inhibition of G372A-FVIIa and FVIIa ... complex.The amino acid residues that determine the zymo-genicity of free FVIIa are as interesting as thoseinvolved in the TF-induced allostery. Amino acid resi-dues in FVIIa that are involved in the ... forTF binding and ⁄ or the cofactor effect [13]. In terms of intramolecular propagation of the TF-induced signal,the most interesting mutations are those that onlyaffect activity of the FVIIaÆTF...

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