Báo cáo khoa học: Amino acid limitation regulates the expression of genes involved in several specific biological processes through GCN2-dependent and GCN2-independent pathways ppt
... devoid of a given essential
amino acid.
Our data suggest that the GCN2 pathway is directly
involved in the regulation of amino acid and protein
metabolism, as many of the genes involved in these
processes ... that the mecha-
nism underlying the recognition of protein quality acts
through the sensing of free circulating amino acids
resulting from...
... FEBS
bean and soybean. When binding of arginine in the
presence of tRNA was investigated, some changes in
the binding architecture were observed [35], in that
N(153:Y), in addition to interacting with ... significantly. In contrast to l-canavanine,
it is the bridging N of the guanidine group that is
replaced by the heteroatom in l-thioarginine, locking
the guani...
... genes involved in PUFA biosynthesis follow-
ing the completion of the genome sequence of the EPA
and DHA producing diatom T. pseudonana [17]. Levels
of EPA and DHA in this organism are in the range ... encodes a protein of
474 amino acids. Alignment with the corresponding
genomic sequence confirmed the presence of a 99 bp
intron in the TpdesO gene. Th...
... matter
of hours.
As a demonstration of the biological relevance, this
methodology was used to model the P-selectin-binding
domain of the mucin-like glycoprotein PSGL-1 [73,74].
This ligand is involved ... in ammation in
mammalian brain tissue both in vitro and in vivo,
including in the detection of cerebral malaria.
Retooling of this reporter system also allow...
... calling Perl routines from the Java API.
Perl routines take care of the bulk of querying ency-
clopedia entries to the MediaWiki software (which
in turn queries the database) and efficiently parsing
the ... based on the link
structure of the articles);
3. computing paths in the Wikipedia categoriza-
tion graph between the categories the articles are
assigned to;...
... that these vectors reflect the sum of
the contextual behavior of a word’s underlying
senses, i.e. they are mixtures of all senses occur-
ring in the corpus.
However, since reconstructing the ... mixtures of all its senses. Inducing
a word’s senses therefore involves the difficult
problem of recovering the sense vectors from
the mixtures. In this paper we argue...
... occur-
rence of/ L In the case of the generation relation
between flipping the switch and turning on the light,
C will include that the wire, the switch and the bulb
are working.
Although ... that the generatee affects
the execution of the generator, so the enabled action
affects the execution of the enabling action. Consider
the difference in...
... assignment. In the case of
to gun
down
the ambiguity of to is enhanced by the ambiguity
of
gun,
and a mistake in tagging
gun
will automatically
lead to an incorrect tagging of
to
as ... between the
verb and the particle in order to optimize the perfor-
mance of the tagger.
3. THE EXPERIMENT
3.1. DATA
The first step in testing this hypothesis...
... terms of number of words,
f(a)
the frequency of a in the corpus,
Ta the set of candidate terms that contain a,
P(T~)
the number of these candidate terms.
At this point the incorporation of the ... these strings,
C-value
is calculated
resulting in a list of candidate terms (ranked by C-
value as
their likelihood of being terms). The length
of the...
... by the binding of ornithine. The loca-
tion of the common intercept in mixed-type inhibition
systems depends on the actual and relative values of a
and b. An intercept in the upper right-hand ... (formation of an enzyme–amidino interme-
diate and release of ornithine in the absence of
glycine), product formation by CyrA was investigated
in the presence...