... Germany2 Research Group Modeling of Biological Systems, German Cancer Research Center and BioQuant Center, Heidelberg, Germany3 Department of Parasitology, Berlin, Germany4 Institute of Pathology, ... many cell types. A myr-iad of stimuli can activate these kinases, which, inturn, activate many other transcription factors andregulators of transcription, controlling the expression of many ... activation of ERK (transient) and p38 (sustained).Both models present weak and transient ERK andstrong and sustained p38 activation.Changing the Av17 stimulus shows that bothERK and p38 control...