... renal failure was defined as calculated creatinineclearance less than 50 ml/minute. The parameters needed tocalculate the creatinine clearance were always available in both the PB-U and the ... acquisition, analysis of the data, statistical analysis and drafting of the manuscript.BC was responsible for data acquisition, analysis of the data,and drafting of the manuscript. JD was responsible ... physicians had to order a 'vancomycin loading dose' and a 'vancomycin dose accord-ing to plasma level', without having to adjust anything, whichvirtually eliminates the risk of...