Báo cáo khoa học: Flexibility and communication within the structure of the Mycobacterium smegmatis methionyl-tRNA synthetase Henrik Ingvarsson and Torsten Unge potx
... methylation [8], and the cleavage
of DNA by alkali [31]. The method allows easy detection of
DNA–protein interactions via the N7 position of guanines
in the major groove and via the N3 position of adenines ... results, and the
results of others, highlight the pleiotropic effects that TSA
administration has on chromatin structure and on gene
expression.
Materi...
... coiled-
coil or other interchain helical structure. Extension of
the binding studies to the other LCs showed that
LC8-induced DIC dimerization enhances the binding
affinity of the dimeric DYNLT and the resulting
complex ... DIC dimerization and the binding of light
chains and other components of the motor complex
including the heavy chain and p150
Glued
subunit...
... in the presence of increasing concentrations of
both K-49 and RDS1643, and was analyzed using the
Yonetani–Theorell plot (Fig. 2). The results show that
both slope and intercepts of the plots of ... both RNA and DNA
dependent; and (b) RNase H activity that selectively
hydrolyzes the RNA strand of the RNA:DNA hybrid
formed during synthesis of the minus (–) s...
... affect the rate of transcription
[33], and ever since the clear demonstration of a causal
relationship between hypermethylation of the promoter
of tumor suppressor genes and the development of
cancer, ... in the unique
N-terminus, (b) binding of the N-terminus by ancillary
factors, (c) the lack of a negatively functioning module
that is present in the N-termi...
... per-
mutation in the book, and then chooses the one with
the highest frequency as the correct reconstruction
of the entry. In this way, we identify the form of the
index entries as appearing in the book, ... segments, and counts the number of segments
that include the phrase (within document frequency);
the length of the phrase (length of phrase); and...
... the action of 20E and may act
to protect the ASGs from early execution of PCD during the feeding stage.
GOD was localized in the inner cavity of the gland, and was discharged to
the outside of ... with the liquid silk in the silk
glands, indicating that trehalase is produced by the silk
gland cells and is localized to the cavity of ASGs
[19,20]. The silk...
... suggesting that the
level of GFP–PrP
C
transgene expression was dependent
on the colour of the background of the animal. The
fusion protein was found only in the NIL and not in
the AL of black- and white-adapted ... examine the effect of the overexpressed Xenopus
GFP–PrP
C
protein on the biosynthesis and processing
of POMC as well as the secretion of...
... the basis
to further investigate the regulation of the cdc2
promoter by LINC in different phases of the cell cycle.
Although, so far, only the cdc2 promoter has been
analyzed, the promoters of ... serum-starved
cells, and that both parts of the CDE-CHR element
are required for binding of the complex. These find-
ings are consistent with previous studies that reporte...
... W1 is the lemma of the
word for which Rel holds, W2 is the lemma of the
other open-class word involved, Prep is the prepo-
sition or particle involved and Pos is the position
of W1 in the corpus. ... Lexi-
cographers need all the help they can get because
the analysis of meaning is the second hardest part
of their job (Kilgarriff, 1998), it occupies a large
sha...
... 2010 The Authors Journal compilation ª 2010 FEBS
Flexibility and communication within the structure of the
Mycobacterium smegmatis methionyl-tRNA synthetase
Henrik Ingvarsson and Torsten Unge
Department ... amide groups of Ile128 and Arg129.
Despite these differences in the coordination of the res-
idues in the tip, the fold of the loop is...