... form the phenolic substrate-binding site of the enzyme, whereas the T2 and the T3-pair coppers form the trinuclear site that is responsible for binding and reduction of the molecular oxygen. The ... which is Asp in TaLcc1, and Glu in MaL. In addi-tion, the crystal structure of TaLcc1 does not have a chloride attached to the T2 copper, as observed in the crystal structure of MaL. The unique ... against hydrolysis, and improving the Fig. 1. (A) The crystal structure of TaLcc1as a surface model. Domain A is presented in blue, domain B in green, and domain C in yellow. The N-glycans are...