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Tài liệu Báo cáo Y học: Structure of the O-polysaccharide and classification of Proteus mirabilis strain G1 in Proteus serogroup O3 potx

Tài liệu Báo cáo Y học: Structure of the O-polysaccharide and classification of Proteus mirabilis strain G1 in Proteus serogroup O3 potx

Tài liệu Báo cáo Y học: Structure of the O-polysaccharide and classification of Proteus mirabilis strain G1 in Proteus serogroup O3 potx

... Structure of the O-polysaccharide and classification of Proteus mirabilis strain G1 in Proteus serogroup O3 Zygmunt Sidorczyk1, Krystyna Zych1, Filip V. Toukach2, Nikolay P. Arbatsky2, ... showed the presence o f2-amino-2-deoxygalactose and lysine. The Dconfiguration of GalA and GalN was determined by GLC of the acetylated (S)-2-butyl glycosides and the Lconfiguration of lysine by ... LPS of P. mirabilis strains from two other serogroups contain-ingD-GalA6(L-Lys) in the O-polysacch aride or in the coreregion.Keywords: Proteus mirabilis; O-polysaccharide; lipopoly-saccharide;...
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Tài liệu Báo cáo Y học: Insights into the reaction mechanism of Escherichia coli agmatinase by site-directed mutagenesis and molecular modelling ppt

Tài liệu Báo cáo Y học: Insights into the reaction mechanism of Escherichia coli agmatinase by site-directed mutagenesis and molecular modelling ppt

... whole loops and the two connecting aminoacids at the beginning and the end, were mutated to glycines and, after remodelling back to their side chains in agma-tinase, the whole hydrogen bond ... environ-ment of tryptophan residues is essentially conserved in the mutant enzyme. On the other hand, the absence of majordifferences in the CD spectra of the wild-type and D153Nagmatinases indicates ... separately alignedwith the sequences of 1CEV and 1RLA and pasted into the structural alignment. The alignment was then corrected byhand. Since the sequences of the two arginases and agmatinase...
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Tài liệu Báo cáo Y học: Tissue factor pathway inhibitor A possible mechanism of action doc

Tài liệu Báo cáo Y học: Tissue factor pathway inhibitor A possible mechanism of action doc

... anevidence of the hypothesis.Fig. 5. Verification of the hypotheses for TFPI inhibitory mechanism.(A) Verification of the hypothesis of the enzyme–product complexinhibition by TFPI. Factor Xa is inhibited ... the data of the study[18] (see below). In other cases the binding of factor Xa toTFPI was assumed to be plain bimolecular reaction basingon the data of the study [8]. The model including inhibition ... 1A), the authors of the study [8] introduced a hypothesis of inhibitory action of TFPI on the enzyme–product complexas the predominant pathway of TFPI action (Scheme 2). The second step in the...
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Tài liệu Báo cáo Y học: Studies on the nonmevalonate pathway of terpene biosynthesis The role of 2C-methyl-D -erythritol 2,4-cyclodiphosphate in plants docx

Tài liệu Báo cáo Y học: Studies on the nonmevalonate pathway of terpene biosynthesis The role of 2C-methyl-D -erythritol 2,4-cyclodiphosphate in plants docx

... the observed very slow exchange of the HA-hydrogen of IPP. In both cases, scrambling of the label takes place within the IPPpool and the error is then transcribed into the DMAPP pool by the normal ... undetected,probably because of the inadequacy of the analytical toolsemployed in earlier work using a14C label. In all the cases in which such a scrambling was observed it was usuallyascribed to a lack of ... exchange (2% of the isomerization rate) of the methyl group of IPP and the (Z)-methyl group of DMAPP, and an even slower exchange(0.5% of the isomerization rate) of the olefinic hydrogen of DMAPP...
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Tài liệu Báo cáo khoa học:

Tài liệu Báo cáo khoa học: "What lies beneath: Semantic and syntactic analysis of manually reconstructed spontaneous speech" pdf

... concep-tion of transformation (Harris, 1957). In this view, the original verbatim string is the surface form of the sentence, and as in linguistic theory should beconstrained in some manner ... directly. Such analysis not only in- forms us of what the speaker intended to commu-nicate, but also reveals insights into the types of er-rors speakers make when speaking spontaneously and where ... underlying constituentdependencies and parser interpretation. We canquantify these changes in part by comparing the internal context-free structure between the twosets of parses.We compare the...
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Tài liệu Báo cáo khoa học:

Tài liệu Báo cáo khoa học: "Prosodic Aids to Syntactic and Semantic Analysis of Spoken English" ppt

... parser's input and again to deter- mine the syntactic structure of sentences by seeking structures that are intonationally and syntactically consistent. The work described here is in progress. The ... purpose of utteranc- es and their domain context, it is then possible to correct some of the insertion and mis-recognised word errors from the SR and determine the com- municative intent of the ... present some results of employ- ing two types of prosodic information, namely pitch and pause, to assist syntactic and semantic analysis during parsing. 1. INTRODUCTION In attempting to merge speech...
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Tài liệu Báo cáo khoa học:

Tài liệu Báo cáo khoa học: "Guided Learning for Bidirectional Sequence Classification" ppt

... U is the score of an action. In other words, the score of an hypothesis is the sum of the score of the most recent action h.A and the scores of the top hypotheses of the context states. The score ... directly de-pends on the score of the action, but not on the score of the hypothesis. On the other hand, the score of the hypothesis is used to maintain top partial results foreach span.We brie y ... the gold standard, we update P and Qas in Algorithm 1. Otherwise, we update the weightvector in the Perceptron style, by promoting the fea-tures of the gold standard action, and demoting the features...
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Tài liệu Báo cáo Y học: Functional analysis of DM64, an antimyotoxic protein with immunoglobulin-like structure from Didelphis marsupialis serum pdf

Tài liệu Báo cáo Y học: Functional analysis of DM64, an antimyotoxic protein with immunoglobulin-like structure from Didelphis marsupialis serum pdf

... found in DM43 first threedomains and are present in the inhibitory receptors of Fig. 6. Inhibition of in vitro cytotoxicity of myotoxins I or II by DM64.Cytotoxicity was analyzed in vitro using ... a1B-glycoprotein, indicating the presence of five immunoglobulin-like domains. DM64 neutralized both the in vivo myotoxicity and the in vitro cytotoxicity of myotoxins I (mt-I/Asp49) and II (mt-II/Lys49) ... sequences. The conserved aromatic residues phenylalanine and tyrosine typical of the Ig-fold are bold in each domain.Fig. 5. Inhibition of in vivo myotoxicity of myotoxins I or II by DM64.Groups of...
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Tài liệu Báo cáo Y học: A Raman optical activity study of rheomorphism in caseins, synucleins and tau New insight into the structure and behaviour of natively unfolded proteins pot

Tài liệu Báo cáo Y học: A Raman optical activity study of rheomorphism in caseins, synucleins and tau New insight into the structure and behaviour of natively unfolded proteins pot

... ±Birkprotease inhibitors [5], metallothioneins [6], prothymosina [7], a bacterial ®bronectin-binding protein [8], the brainprotein a-synuclein together with the related proteinsb-synuclein and c-synuclein ... structures of the caseins,synucleins and tau may be envisaged as more open,hydrated, longer-chain (and nonglobular) versions of the structure of the Bowman±Birk inhibitor in Fig. 6 . The X-ray crystal ... 1320 cm)1to PPII structure relies mainly on the evidence outlined above. In view of the c lose similarity of the ROA spectra of the casein, synuclein and tau proteins shown in t his paper, wehave...
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Tài liệu Báo cáo Y học: Molecular modeling of the dimeric structure of human lipoprotein lipase and functional studies of the carboxyl-terminal domain docx

Tài liệu Báo cáo Y học: Molecular modeling of the dimeric structure of human lipoprotein lipase and functional studies of the carboxyl-terminal domain docx

... the catalytic site in the N-terminal domain of one subunit and the substrate recognition site in the C-terminal domain of the other face each other, thereby bringing together the substrate-binding ... (Arg405, Lys407,Lys413, Lys414, Lys422, Lys428, and Lys430) oriented in the same direction with the heparin-binding domain at the N-terminal end [14]. The other is a cluster of tryptophans(Trp390, ... (40% similarity) and are28% identical in the C-terminal domain (38% similarity). The catalytic efficiency and heparin-binding functions of the N-terminal domain have been extensively studied[13,14]....
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