... 2002
Human and
Drosophila
UDP-galactose transporters transport
UDP-
N
-acetylgalactosamine in addition to UDP-galactose
Hiroaki Segawa*, Masao Kawakita and Nobuhiro Ishida
Department of Physiological ... detected in a position and
stage-speci®c manner during Drosophila development [24].
Heparin-like glycosaminoglycans that contain galactose and
N-acetylgalactosa...
... 2-arachidonoylglycerol (2-AG), the cannabinoid CB
1
and CB
2
receptors, and one of the enzymes mostly
responsible for endocannabinoid hydrolysis, the fatty acid
amide hydrolase (FAAH). By using a very ... Parkinson’s disease) and pain [1], and to play a
down-regulatory role on the immune system [2]. Indeed,
cannabinoids exhibit immunosuppressive properties and
in vitro they weak...
... amino acid-
rich media included: YPD [yeast extract and Bactopeptone
(YP) containing 2% dextrose]; YPA (YP containing 0.05%
glucose and 2% potassium acetate); and YPG (YP
containing 3.5% galactose).
Phospholipase ... PtdEtn-PLD
activity in response to inositol and/ or choline in
the medium. Wild-type and spo14D mutant
strains were grown to mid log-phase in SC
medium in th...
... process in
mammals during late embryogenesis [6,7]. The methylation
pattern is created by de novo methylation and demethyla-
tion of the DNA, and maintained during mitosis by
maintenance methylation ... groups are always introduced, one
slowly by Dnmt3a or by de novo methylation catalyzed by
Dnmt1 and the second one very fast. Therefore, this effect
can only double the rate of DNA met...
... other amino-
glycosides, as kanamycin A, neomycin B and a synthetic
neomycin-neomycin dimer have been shown to induce
fragmentation of tRNA
Phe
at Y3 7 and additionally at
m
7
G46 in the variable ... were observed and they disappeared after removing
wybutine. Interestingly, enhancement of wybutine fluores-
cence was observed after addition of neomycin B or
kanamycin A to tRNA
Ph...
... [6], prothymosin
a [7], a bacterial ®bronectin-binding protein [8], the brain
protein a-synuclein together with the related proteins
b-synuclein and c-synuclein [9±12], a nd the brain protein
tau ... residues, as
observed in the caseins [3], synucleins [10], tau [14],
prothymosin a [7] and the ®bronectin-binding protein [8],
and also in typical chemically denatured proteins [56±58]....
... might in uence
antibacterial activity that differ between opistoporin 1 and
pandinin 1 are the hydrophobicity (pandinin 1–0.1214,
opistoporin 1–0.1652) and the hydrophobic moment, which
is nearly ... recently described
in the venom of spiders and insects.
Parabutoporin and opistoporin 1 were synthesized
chemically and preliminary studies on antibacterial activity
showed that the...
... atom. Tyr183 is
believed to assist Asp125 in this function by hydrogen
bonding to the carbonyl oxygen of the N-acetyl group. In
this specific orien tation the N- acetyl carbonyl oxygen
atom is in ... classes.
Role of Tyr183 in catalysis
In previous crystallographic studies it was shown that the
hydroxyl side chain of Tyr183 is within hydrogen bonding
distance of the N-acetyl carb...
... full-length proteins.
Keywords: calretinin; calcium; calbindin D
28k
; EF-hand;
NMR secondary structure.
Calretinin (CR) and calbindin D
28k
(Calb) are homologous
calcium-binding EF-hand proteins with ... C.P.
(1999) A kinetic and stereochemical investigation of the role of
lysine-32 in the phenylpyruvate tautomerase activity catalyzed by
macrophage migration inhibitory factor. Biochemi...
... Dialogue and Understanding Development Environment,
mapping Business Process Models to Information State Update dialogue
systems
Oliver Lemon and Xingkun Liu
School of Informatics
University of Edinburgh
olemon,xliu4 ... recognition, interpretation, and production) the
human operator is responsible for:
contextual interpretation of incoming spee c h
maintaining a nd updating dialogu...