Tài liệu Báo cáo khoa học: "Extraction and Approximation of Numerical Attributes from the Web" pdf

... of the methods aresuitable for retrieval of numerical attributes. How-ever, most of them do not exploit the numerical nature of the attribute data.Our research is related to a sub-domain of ... evaluation, since the nature of the data is different from that of the QA dataset. Most of the questions asked over the Web target named entities like speciﬁc car brands,places and actors. There is usually ... (e.g., the height of a person), whilefor others it is only the center of a distribution(e.g., the weight of a coffee cup). Questionswith no trusted and exact answers were eliminated. From the...

Tài liệu Báo cáo khoa học: Structure and function of active chromatin and DNase I hypersensitive sites pdf

... C (1989) The limits of the DNase I-sensitive domain of the human apolipoproteinB gene coincide with the locations of chromosomalanchorage loops and deﬁne the 5¢ and 3¢ boundaries of the gene. ... Since then there has been an explo-sion of papers on the multitude of chromatin modiﬁca-tions and the factors that can either create orrecognize them. We now have a very detailed picture of the ... bp intervals. The lighter colour shadesdepict the bottom half of the nucleosome, and the exploded viewbelow the octamer depicts the arrangement of the histones con-tacting 73 bp of DNA within...

Tài liệu Báo cáo khoa học: miRNAs and regulation of cell signaling pptx

... grants from the Scientiﬁc Fund of the Ministry of Education,Science and Culture of Japan (G.T.); the Program forPromotion of Fundamental Studies in Health Sciences of the National Institute of ... regulation of signal cascades and the physiological and pathological roles of miRNAs. Hence, furtherinvestigations aiming to elucidate the mechanisms and signal cascades that regulate the expression of miRNAs ... stimulates the production of these miR-NAs and thus represses the expression of their targetgenes. TGF-b signaling is known to be involved in the epithelial–mesenchymal transition (EMT). The transcription...

Tài liệu Báo cáo khoa học: Expression and secretion of interleukin-1b, tumour necrosis factor-a and interleukin-10 by hypoxia- and serum-deprivation-stimulated mesenchymal stem cells Implications for their paracrine roles ppt

... and secretion of IL-10Because of the lack of secretion of the inflammatorycytokines IL-1b and TNF-a from hypoxia ⁄ SD-stimu-lated MSCs, as well as the significant anti-inflamma-tory effects of MSCs, ... in the presenceor absence of LPS for the indicated number of h. *, nonspecific band. (C) The results of ELISA analysis of supernatants from MSCsafter hypoxia ⁄ SD stimulation for 12 h in the presence ... the phosphorylation and ubiquitin-related degradation of IjB. The active form of NF-jBp65 is then released and translocated into the nucleus to activate the tran-scription of IL-1b and TNF-a. In this...

Tài liệu Báo cáo khoa học: Investigation and prediction of the severity of p53 mutants using parameters from structural calculations pptx

... Among the 2314 mutants, 1148 were localized in the central coredomain of the protein and were used for training and evalua-tion of our prediction algorithm. Of the eight promoters, westudied the ... prediction of the severity of p53 mutants. The method was trained on a set of known mutants and subsequently evaluated on anotherset. The method is based on parameters reﬂecting the bio-chemical and ... powerful method, and several algorithms have been developed recently [4–7]. The major drawback of these analyses is the lack of information regarding the activity or loss of activity of the target...

Tài liệu Báo cáo khoa học: Isolation and characterization of four type 2 ribosome inactivating pulchellin isoforms from Abrus pulchellus seeds docx

... comprising the two sugarbinding pockets in the pulchellins (Fig. 3).In order to compare the similarity of the A- and B-chains of the four isoforms, a pairwise alignmentwas performed and the values of ... Taken together with the inability of P III and P IV to inhibit hemagglutination in vitro in the presence of this sugar, these data suggest that the bind-ing and uptake of these two isoforms does ... separate the P III and P IV isoforms from the eluate P III ⁄ P IV (Fig. 1C).Isoelectric focusing gave pI of 5.8, 5.7, 5.5 and 5.2 for the four isoforms respectively.Secondary structure of the pulchellin...

Tài liệu Báo cáo khoa học: Expression and function of Noxo1c, an alternative splicing form of the NADPH oxidase organizer 1 doc

... as the insert region is located between the pair of primers(Fig. 2A). The lengths of the PCR products of Noxo1b and Noxo1c were 225 and 240 bp, respectively. Todelineate the difference in the ... inregulation of Nox3, the role of the PX domain in Nox3activity remains unknown.In the process of cloning of human Noxo1, somespliced transcripts of the NOXO1 gene have beenidentiﬁed [15,17–19]. They ... show the expres-sion of alternatively spliced transcripts of the NOXO1gene, by PCR using variant-speciﬁc primers, and the roles of the protein products in activation of Noxoxidases.Results and...

Tài liệu Báo cáo khoa học: Production and characterization of a secreted, C-terminally processed tyrosinase from the ﬁlamentous fungus Trichoderma reesei ppt

... these states are alternated, has beenproposed [16]. The met state is the resting state of the enzyme, and in the absence of substrate about 85–90% of the enzyme is in this state [16]. Both the ... either from the mass ﬁngerprint orpuriﬁed peptides, covered 60.3% of the sequence, and the masses of cyanogen bromide fragments, including the N-terminal and C-terminal ones, covered 94.9% of the ... available, and will enable more detailed analy-sis of the exact reaction mechanisms. The tyrosinasestructure, wherein the active site was located at the bottom of a large vacant space and one of the...

Tài liệu Báo cáo khoa học: Cloning and characterization of CBL-CIPK signalling components from a legume (Pisum sativum) ppt

... represent the UTRs. The position of ATG and TAA are marked. The numbers below the lines and the above boxes indicate the sizes(bp) of introns and exons, respectively.Stress-induced CIPK from pea ... of a large family of CIPK and CBL genes hasbeen reported in Arabidopsis and rice [15]. However, the details of the role of these proteins and the inter-Stress-induced CIPK from pea phosphorylate ... MgCl2without addition of any exogenous Ca2+.Phospho-amino acid analysis The phosphorylated 26-kDa band of PsCBL and the 58-kDa band of PsCIPK were separately eluted from the gel and hydrolysed in...

Tài liệu Báo cáo khóa học: Cloning and characterization of two distinct isoforms of rainbow trout heat shock factor 1 ppt

... evidence for existence of twodistinct HSF1 isoforms in rainbow trout and the formation of heterotrimers of these isoforms in vitro.Materials and methodsCell culture and animalsRainbow trout ... 10.0;GAPEXT,0.05;GAPDIST,8;MAXDIV,40;ENDGAPS,off;NOPGAPS,off;NOHGAPS,off.Graphicaloutput of the bootstrap ﬁgure was produced by the programTREEVIEW.Isolation of RNA and RT-PCR analysisTotal RNA was isolated from RTG-2 cells and ... weredetected in the lanes containing HSF1a–HA (Fig. 7A, lanes1 and 3). The apparent molecular masses of the bands were 200 kDa and  70 kDa. These molecular masses corres-pond to the sizes of an HSF1...

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