... from the Ministry of Education, Culture, Sports, Science and Technology of Japan, a grant from the program‘Research for the Future’ of the Japan Society for the Promotion of Science, and the ... tissuefluid and edema in the brain may be dangerousbecause the volume of the brain tissue is tightly limitedby the cranial bone. This limitation is unique amongtissues in the body, and the risk of ... deletion of the hypoxia-response element of the VEGF-A genepromoter and a reduction in VEGF-A expressioncause the degeneration of motor neurons. This studyraised the possibility that the VEGF and...