... presence of three distinct domains: the rigidCORE-domain and two smaller peripheral domains ormobile parts, the NMP-binding site and the LID-domain[4]. The NMP-binding site has many intermolecularcontacts ... wereobtained by simple rotation of the same model. The flexible LIDdomain appears at top of the three figures, NMP-binding site and ATPbinding domain are displayed, NH2- and COOH-termini are alsoindicated.Ó ... Within the AMP bindingdomain, some amino acid residues are well conserved(L59, F87, R89) while two others, a leucine and a valine,are replaced by V35 and I60, respectively. A Mg2+binding...