... of PPARc tar-get genes is increased in WAT of TG mice, suggestingthat PPARc might be activated more in WAT of TGmice than in WAT of WT mice.Serum levels of triglyceride, glucose, leptin and insulin, ... we show, for the first time, that PGD2isinvolved in the activation of adipogenesis and regula-tion of insulin sensitivity in vivo. Further characteriza-tion of the role of PGD2 in adipocyte ... washing, the sections were incubated with the biotinylated goat anti-(rabbit IgG) for 30 min (Vector Laboratories, Burlingame,CA, USA), and this was followed by staining with the avidin–biotin–peroxidase...