Tài liệu Báo cáo khoa học: The role of antioxidants in the cytotoxicity of chemotherapeutic drugs pptx
Tài liệu Báo cáo khoa học: Domain deletions and substitutions in the modular protein evolution doc
... domain deletions are more com-mon at either of the protein termini, and that theiroccurrence is slightly higher at one of the termini,depending on the number of domains in the proteinand the ... C−terminusLength of the N terminus in % of the deleted domainLength of the C terminus in % of the deleted domainPfam, N−terminus Pfam, C −terminusNumber of occurencesNumber of occurences2500035000550000 ... size of the deleted domain was calculated for the proteins with the complete arrangement. To take into account the variability of the length of the complete domain, the length of the N-terminal...
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Tài liệu Báo cáo khoa học: Tryptophan tryptophylquinone cofactor biogenesis in the aromatic amine dehydrogenase of Alcaligenes faecalis Cofactor assembly and catalytic properties of recombinant enzyme expressed in Paracoccus denitrificans pptx
... substrate carbinolamine intermediate;III, iminoquinone intermediate; IV, product Schiff base intermediate;V, aminoquinol intermediate. In the oxidative half-reaction the ami-noquinol intermediate ... substrates. The lack of inhibition observed with benzylamine (Fig. 5A) in comparison to the inhibition observed with tryptamine(Fig. 5B) suggests differences in binding of the twosubstrates within the ... kinetically in uentialionizations were identified in plots of klim⁄ Kd of pKavalues 7.1 and 9.3,again with the maximum value realized in the alkaline region. The poten-tial origin of these kinetically...
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Tài liệu Báo cáo khoa học: Human intrinsic factor expressed in the plant Arabidopsis thaliana doc
... at the internal site …PSNPflGPGP. The key properties of the preparation obtained were identical to those of native IF: the binding curves of vitamin B12to recombinant IF and gastricIF were the ... this Cblbinder hampers the uptake of the minute amounts of the vitamin present in food. Only around 1% of the ingestedCbl can be absorbed by passive diffusion [6].Classical vitamin B12deficiency ... (IF) is the gastric protein that promotes the intestinal uptake of vitamin B12. Gastric IF from animalsources is used in diagnostic tests and in vitamin pills.However, administration of animal...
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Tài liệu Báo cáo khoa học: Moult cycle-related changes in biological activity of moult-inhibiting hormone (MIH) and crustacean hyperglycaemic hormone (CHH) in the crab, Carcinus maenas From target to transcript ppt
... biological activity of MIH and CHHduring precisely timed stages of the moult cycle of Carcinusto determine changes in: (a) potency of these peptides in repressing ecdysteroid synthesis; (b) receptor ... level. In view of these observations, we also investigated levels of MIH and CHH peptides in the sinus gland and levels of transcripts in XO neurones during the moult cycle, to seewhether significant ... oraccumulation of peptides in the SG, we quantified steady-state levels of peptides in the SG during the moult cycle.When levels of MIH in premoult SG were compared tothose in intermoult, there was...
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Tài liệu Báo cáo khoa học: "THERE STILL IS GOLD IN THE DATABASE MINE" potx
... and mine it very deeply, not necessarily discovering every aspect of the domain but requiring that the various aspects be integrated with one another to produce a coherent whole. Even in the ... of our art? Instead of assuming that the problem is one of using typed English to access and/or update a file or files in a single database system, let us define a spectrum of potential natural ... ambiguity (the word "yield" is ambiguous if there is both financial and productivity data in the knowledge base), and other complex linguistic phenomena. Let us go on to define the other...
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Tài liệu Báo cáo khoa học: A role of miR-27 in the regulation of adipogenesis ppt
... obese mice In order to gain insights into the potential biologicallyrelevant role of miR-27 in the regulation of adipose tis-sue functions in vivo, we examined the expression of miR-27 in the genetically ... together, these results illustratea critical and specific role of miR-27 in the regulation of adipogenic differentiation.miR-27 prevents the induction of PPARc andC⁄EBPa In order to delineate ... differentially regulatedor play a role under obese conditions in vivo. In the current study, we investigated the role of miRNAs in adipogenic differentiation using the mouseembryonic fibroblast-derived...
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Tài liệu Báo cáo khoa học: Local stability identification and the role of a key aromatic amino acid residue in staphylococcal nuclease refolding pdf
... can therefore postulatethat, when the segment beyond W140 was removed, the secondary structure of the protein disintegrated. Using the peak at 222 nm of the wild-type protein as an index of helical ... significant role in maintainingSNase tertiary structure.Our CD and DSC data show that the W140 in SNase is the amino acid responsible for the stability of the whole protein. However, in comparison ... 3).SummaryTrp140 located in the C-terminal loop of SNase playsan important role in protein stability and conforma-tional integrity. During protein unfolding ⁄ refolding, the addition of 2.5 protons (both...
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Tài liệu Báo cáo khoa học: A role for the intersubunit disulfides of seminal RNase in the mechanism of its antitumor action docx
... thusblocking protein synthesis and leading cells to death. The current model proposed for the mechanism of antitumouraction of BS-RNase is based on the ability of the proteinto resist the neutralizing ... hypothesize that the cytotoxicactivity of the latter monomers was due to the presence in these proteins of disulfide bonds, with their potentialchemical instability. It is well known that in the ... and the intersubunit disulfides thatlink the two subunits of BS-RNase. Monomeric derivatives of the protein are inactive as cytotoxic agents when they areprepared by reductive cleavage of the intersubunit...
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Tài liệu Báo cáo khoa học: Key role of the loop connecting the two beta strands of mussel defensin in its antimicrobial activity docx
... obtained by other groupswho also point to the role of the connecting loop of the b-hairpin of defensins. A combination of mutationalanalysis [35] and structural analysis of the plant defensinRs-AFP1 ... moleculecomprising Ôresidues in the protruding domain consisting of the type VI b-turn and the first part of b-strand 3Õ (i.e. the b-hairpin loop and part of the adjoining b-sheet) andÔresidues in the loop ... is not possible to infer whether the key role of the b-hairpin loop of MGD1 (loop 3) in antimicrobial activity of MGD1 is of general value in the mechanism of action of defensins. However, our...
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Tài liệu Báo cáo khoa học: Electrostatic role of aromatic ring stacking in the pH-sensitive modulation of a chymotrypsin-type serine protease, Achromobacter protease I pdf
... thisprotease at pH9 [10]. Further interest in the aromaticstacking is in the role of the electrostatic properties in enzymatic catalysis of API, and in distinguishing the functionally catalytic quadruple ... position. In the struc-tural deviation, the solvent ASA of the side-chain of His210increased with the decrease in size of the side-chain atresidue 169 (Table 1 and Fig. 3A). However, the ASAs of Asp113 ... size of the side-chain at residue 169 and the pK2showed a clear linear relationship (Fig. 3B). The pK2increased as the size of the residue at position 169 increased. The effect of the size of...
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Từ khóa: tài liệu báo cáo khoa họctài liệu báo cáo nghiên cứu khoa họctài liệu về báo cáo khoa họcbáo cáo khoa học công nghệ phục vụ nông nghiệp và phát triển nông thôn các tỉnh phía bắc 2006 2007 tài liệu phục vụ hội nghịbáo cáo khoa học tài chính côngbáo cáo khoa học số loài quý hiếm tại vườn quốc gia ba bểBáo cáo thực tập tại nhà thuốc tại Thành phố Hồ Chí Minh năm 2018Báo cáo quy trình mua hàng CT CP Công Nghệ NPVchuyên đề điện xoay chiều theo dạngNghiên cứu tổ chức pha chế, đánh giá chất lượng thuốc tiêm truyền trong điều kiện dã ngoạiMột số giải pháp nâng cao chất lượng streaming thích ứng video trên nền giao thức HTTPNghiên cứu vật liệu biến hóa (metamaterials) hấp thụ sóng điện tử ở vùng tần số THzđề thi thử THPTQG 2019 toán THPT chuyên thái bình lần 2 có lời giảiBiện pháp quản lý hoạt động dạy hát xoan trong trường trung học cơ sở huyện lâm thao, phú thọGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANNghiên cứu về mô hình thống kê học sâu và ứng dụng trong nhận dạng chữ viết tay hạn chếĐịnh tội danh từ thực tiễn huyện Cần Giuộc, tỉnh Long An (Luận văn thạc sĩ)Sở hữu ruộng đất và kinh tế nông nghiệp châu ôn (lạng sơn) nửa đầu thế kỷ XIXGiáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtchuong 1 tong quan quan tri rui roNguyên tắc phân hóa trách nhiệm hình sự đối với người dưới 18 tuổi phạm tội trong pháp luật hình sự Việt Nam (Luận văn thạc sĩ)Đổi mới quản lý tài chính trong hoạt động khoa học xã hội trường hợp viện hàn lâm khoa học xã hội việt namMÔN TRUYỀN THÔNG MARKETING TÍCH HỢP