... orientation of for-
eign words. Identifying the semantic orienta-
tion of words has numerous applications in the
areas of text classification, analysis of prod-
uct review, analysis of responses ... semantic orientation
of any given word.
3.1 Multilingual Word Network
We build a network G(V, E) where V = V
en
∪ V
fr
is the union of a set of English and foreign words.
E is a set...
... Software Tool designed
and implemented by the authors to analyze
Modern Greek Language (~AnuoTL~'). This
system assigns grammatical ~lasses (parts
of speech) to 95-98% of the words of ... ending" of each
word.
Accentual scheme
The "accentual scheme" of
the
word
reflects the position of the stress on
the word; The stress may come only on one
of the l...
... determined by
the rate of association. It should be noted that quanti-
tative analysis of the more rapid phase of association
requires measurement of the binding on time scales of
minutes, a time ... presence of
unlabeled PCSK9 (Fig. 4A). In the presence of a high
concentration of unlabeled wild-type PCSK9, the half-
time of the rapid phase was reduced from 19 to 16 min
and...
... analysis of purified PhyH, PhyH-DI and PhyH-DII. Lane
M, molecular weight markers; lane 1, culture supernatant of PhyH;
lane 2, culture supernatant of PhyH-DII; lane 3, culture supernatant
of PhyH-DI; ... Environmental factors that affect the catalytic activities of PhyH and PhyH-DII. (A) Effect of 0–5.0 mM Ca
2+
at 37 °C. (B) Effect of pH
at 37 °C. (C) Effect of temperature at...
... University of Bath, UK
2 Department of Biochemistry, University of Wisconsin–Madison, USA
3 Department of Chemistry, University of Wisconsin–Madison, USA
Introduction
Upon catalyzing the cleavage of ... regarding a new class of
surrogates for the phosphoryl group.
Results and Discussion
Sulfonimides as inhibitors of RNase A
We began by determining the ability of three backbo...
... transfer of
phosphate esterified in the 5¢ position of 6-hydroxypu-
rine monophosphate nucleosides [1]. The transfer of
phosphate can lead to phosphorylation of inosine,
guanosine and a number of their ... disappearance of the
heavier inactive peak. Furthermore, FPLC analysis of
the recombinant wild-type cN-II showed the presence
of the tetrameric active form irrespective of...
... K
m
) of PRTFDC1 towards hypoxanthine and guanine was
only 0.26% and 0.09%, respectively, of that of HPRT. This low activity
could be explained by the fact that PRTFDC1 has a Gly in the position of
the ... metabolic consequences
of having HPRT deficiency are an overproduction of
uric acid and elevated levels of PRPP [3]. Patients hav-
ing mutations resulting in partial HPRT defici...
... previously
demonstrated the application of this method to the
determination of the glycan structure of a form of
AFP [10]. However, identification of the details of a
glycan structural change on a ... methylesteri-
fication of sialic acid moieties. All spectra were
obtained in the positive ion mode using MALDI–
quadrupole ion trap (QIT)-TOF MS.
A strategy for discovery of cancer...
... The expression of T-bet has been
seen within a wide variety of tissues and cells in the
Ginbuna crucian carp [27] and, in mammals, in the
lung tissue of mouse and spleen and thymus of human
and ... Activation of
STAT1 induces the transcription factor, T-box
expressed in T cells (T-bet), which is a master regula-
tor of Th1 differentiation [11]. T-bet potentiates the
expression...
... Kessler
Department of Clinical Medicine, University of Oxford, UK
Introduction
The genus Yersinia consists of three pathogenic species
that are agents of a variety of diseases, one of which
was historically ... GTPase-binding
capacity of YpkA and OTUB1-mediated increase in
susceptibility to infection (Fig. 6). The binding of small
GTPases has been reported to be independent o...