... processes. In A. aegypti, the discrete expression
of both AaHR3 and AaHR4 suggests their function in
the regulatory hierarchy in the mosquito fat body dur-
ing vitellogenesis. Indeed, the analysis of the ... Vitellogenin, in the mosquito
Aedes aegypti. Mol Cell Endocrinol 267, 97–105.
20 Velarde RA, Robinson GE & Fahrbach SE (2006)
Nuclear receptors of...
... [4,5]. The remaining 10 subunits of the
mammalian enzyme, namely, IV, Vb, VIa, VIb, VIc, VIIa,
VIIb and VIII are encoded by the nuclear genome,
synthesized in the cytosol and imported into mitochondria
[1–3]. ... Chaps and
150 m
M
NaCl and protease inhibitors [5 lgÆmL
)1
pepstatin
A, 5 lgÆmL
)1
aprotinin, and 1 m
M
phenylmethanesulfonyl
fluoride]) and lysed by three cyc...
... 1C).
Increased nucleolin/C23 protein levels in
Hsp70-transfected cells in response to
H
2
O
2
-induced apoptosis
We next examined the expression of nucleolin ⁄ C23
protein in these cells in response ... oxidative
stress induces nucleolin ⁄ C23 cleavage and apoptosis
[14], and that nucleolin downregulation induces apop-
tosis in C2C12 cells [15]. These data suggest the role...
... sol-
vent B in 2 min, maintenance at 100% solvent B for 6 min,
and linear gradient of 100–5% solvent B in 2 min. The col-
umn was maintained at 30 °C and the flow rate was 300 nLÆ
min
)1
. Detection ... containing a P
1
¢
Lys with the MMP-9 binding site. (C) Interaction of the peptide
substrate PQGKAG containing a P
1
¢ Lys with the MMP-12
binding site.
Tropoelastin degradati...
... interpretation in distinguish-
ing interacting from noninteracting proteins. One
Fig. 1. Schematics of library designs. The helical wheel diagram looks down the axis from the N-terminus to the C-terminus. ... kinetics in the folding
direction, indicating the existence of a folding interme-
diate. In this study, it was ascertained that the first
reaction phase was fast and...
... hydroxylated pyridine ring and of c-N-methyl-
aminobutyrate (CH
3
-4-aminobutyrate) from the pyrrolidine ring of the
molecule. Surprisingly, two alternative pathways for the final steps in the
catabolism ... expect them also to be expressed in a nicotine-
dependent manner. In order to investigate this, we
analyzed the transcription of these genes in the pres-
ence and a...
... values. The Y-axis in the upper
panel shows the cumulative percentage of the values at or below
each interval. The Y-axis in the lower panel shows the number of
sequences scoring within the interval. ... shown in Fig. 2,
the domains obtained can delineate the variations of
the cumulative GC profile and the density distribution
of CpG islands more and more accu...
... pilocarpine, on muscarinic and dopaminer-
gic receptors and on phosphoinositide metabolism in
rat hippocampus and striatum. Neurochem Int 33,
299–306.
21 Viana GSB, Marinho MMF, Sousa FCF, Bruin VMS,
Aguiar ... died during the 24 h observa-
tion period.
Lipid peroxidation and nitrite and GSH content
in the hippocampus of adult rats after
pilocarpine-induced SE
Lipid peroxi...
... unusual in having
two histidine residues (rather than the His-Asn pair
seen in OYE, MR and some of the other member
proteins; Fig. 1B) in the active site for ligand and
substrate binding. For ... productive binding of steroid substrates:
in the first, a (small) sub population of enzyme binds
directly the steroid in the reactive conformation, with
the remainder of t...
... protein uncoupling, G protein
inactivation, and receptor sequestration and degrada-
tion that together regulate the duration and or the
magnitude of the signaling event. In particular, the
rapid ... RGS domain in the amino-terminus of G
protein-coupled receptor kinase 2 inhibits Gq-mediated
signaling. Int J Mol Med 5, 335–340.
20 Chen CA & Manning DR (2001) Regulation...