Tài liệu Báo cáo khoa học: The chitinolytic system of Lactococcus lactis ssp lactis comprises a nonprocessive chitinase and a chitin-binding protein that promotes the degradation of a- and b-chitin doc

... immunoprecipitations and can activate tran-scription of the promoter in transient transfectionassays through the upstream part of the SIRF element.Mutational analysis of a putative CDE ⁄ CHR site in the ... usuallylack a TATA-box and employ multiple transcriptionalstart sites [10,14]. Mutation of either a CDE or a CHR in a promoter leads to the activation of tran-scription in quiescent cells. A ... CHR, yielded a further decrease in regulation. The CDE alone was nottested [41]. The CDE mutation that was assayed wouldalso alter a putative CDE site with the standard dis-tance of four nucleotides...

... phosphorylation. The data presented here suggest that the pro-domain of BMP-2 can alter the signalling properties of the growth factorby modulating the ability of the mature part to interact with the ... Ghayor C, Suzuki A, PalmerG & Caverzasio J (2003) Activation of p38 mitogen-activated protein kinase and c-Jun-NH2-terminal kinaseby BMP-2 and their implication in the stimulation of osteoblastic ... ECD was biotinylated and immobilized on streptavidin-coated BIAcore chips.Ligand binding was first analysed using the maturegrowth factor. The fast association rate and the veryslow dissociation...

... picolinicacid (PA), quinolinic acid (QA) and NAD homeostasis. Indeed, the enzymestands at a branch point of the tryptophan to NAD pathway, and deter-mines the final fate of the amino acid, i.e. transformation ... insertion domain that comprises a short a- helix and a three-stranded anti-parallel b-sheet; the remaining protein residues form the (a ⁄ b)8barreldomain and a C-terminal extension that comprises ... profile and the associated variation in QA and PA levels [7], and other investigations have clearly demonstrated that changes in ACMSD activity are readily reflectedby serum and tissue QA levels...