Tài liệu Báo cáo khoa học: The crystal structure of human a-amino-b-carboxymuconatee-semialdehyde decarboxylase in complex with 1,3-dihydroxyacetonephosphate suggests a regulatory link between NAD synthesis and glycolysis ppt

Tài liệu Báo cáo khoa học: The crystal structure of human a-amino-b-carboxymuconatee-semialdehyde decarboxylase in complex with 1,3-dihydroxyacetonephosphate suggests a regulatory link between NAD synthesis and glycolysis ppt

Tài liệu Báo cáo khoa học: The crystal structure of human a-amino-b-carboxymuconatee-semialdehyde decarboxylase in complex with 1,3-dihydroxyacetonephosphate suggests a regulatory link between NAD synthesis and glycolysis ppt

... participates in picolinic acid (PA), quinolinic acid (QA) and NAD homeostasis. Indeed, the enzyme stands at a branch point of the tryptophan to NAD pathway, and deter- mines the final fate of the amino acid, ... The crystal structure of human a -amino- b -carboxymuconate- e -semialdehyde decarboxylase in complex with 1,3-dihydroxyacetonephosphate...
Ngày tải lên : 18/02/2014, 06:20
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Tài liệu Báo cáo khoa học: The crystal structure of coenzyme B12-dependent glycerol dehydratase in complex with cobalamin and propane-1,2-diol pptx

Tài liệu Báo cáo khoa học: The crystal structure of coenzyme B12-dependent glycerol dehydratase in complex with cobalamin and propane-1,2-diol pptx

... pUSI2E (a G ). DNA segments encoding the b and c subunits of glycerol dehydratase were amplified by PCR using pairs of primers 5¢-CATATGCAACAGACAACCCAAATTCAGCCC-3¢ and 5¢-AGATCTTATCACTCCCTTACTAAGTCGATG-3¢ for ... northern and southern least-squares planes is 5.5°, indicating that the corrin ring of the glycerol dehydratase- bound cobalamin is also almost planar, as compared...
Ngày tải lên : 21/02/2014, 03:20
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Tài liệu Báo cáo khoa học: The capsid protein of human immunodeficiency virus: intersubunit interactions during virus assembly doc

Tài liệu Báo cáo khoa học: The capsid protein of human immunodeficiency virus: intersubunit interactions during virus assembly doc

... The Gag subunits are radially extended, with the N-terminal domain, MA, associated with the inner layer of the viral membrane, and the remaining domains forming the innermost protein layers accor- ding ... spectroscopy. The N-terminal domain of CA (NTD) and the C-ter- minal domain of CA (CTD) are small, globular and mainly helical. NTD contains a- helices 1–7...
Ngày tải lên : 18/02/2014, 06:20
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Tài liệu Báo cáo khoa học: The capsid protein of human immunodeficiency virus: designing inhibitors of capsid assembly ppt

Tài liệu Báo cáo khoa học: The capsid protein of human immunodeficiency virus: designing inhibitors of capsid assembly ppt

... that of wild-type, and those of the assembly-competent mutants E18 7A and N18 3A: the conformations of the two assembly-incompetent mutants (Y16 9A and L21 1A) in the absence of CAI are the same as the ... the protein. This movement creates a large cavity where the aromatic ring of CAP-1 inserts; the urea and dimethyla- monium groups of CAP-1 also m...
Ngày tải lên : 18/02/2014, 06:20
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Tài liệu Báo cáo khoa học: The solution structure of reduced dimeric copper zinc superoxide dismutase doc

Tài liệu Báo cáo khoa học: The solution structure of reduced dimeric copper zinc superoxide dismutase doc

... 1465–1470. 53. Aoki, M., Ogasawara, M., Matsubara, Y., Narisawa, K., Nakamura,S.,Itoyama,Y.&Abe,K.(1994)Familialamyo- trophic lateral sclerosis (ALS) in Japan associated with H46R mutation in Cu/Zn ... black and the residue labels are underlined. Fig. 3. Tube representation of the family of 30 structures of human reduced native SOD obtained with DYANA calculations a...
Ngày tải lên : 21/02/2014, 03:20
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Báo cáo khoa học: The crystal structure of human WD40 repeat-containing peptidylprolyl isomerase (PPWD1) pdf

Báo cáo khoa học: The crystal structure of human WD40 repeat-containing peptidylprolyl isomerase (PPWD1) pdf

... Ciclosporin A inhibits PPWD1 activity against suc-AAPF-pNA. (C) Binding and catalysis of isomerization for the standard substrate suc-AAPF-pNA. Black and red spectra of the Ala residues in the peptide ... response events, including the participation of host CypA in binding the capsid protein Gag of HIV-1 during infec- tion in humans and packaging into HIV virio...
Ngày tải lên : 23/03/2014, 07:20
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Tài liệu Báo cáo khoa học: The central role of CDE/CHR promoter elements in the regulation of cell cycle-dependent gene transcription pdf

Tài liệu Báo cáo khoa học: The central role of CDE/CHR promoter elements in the regulation of cell cycle-dependent gene transcription pdf

... an activating element binding E2F1, -2 and -3. These acti- vating E2Fs cooperate with NF-Y proteins binding to CCAAT-boxes and with Myb proteins associating with a distal Myb site in activating the ... homologs of Caenor- habditis elegans synMuvB proteins and is composed of p130, E2F4 ⁄ 5 and DP1 ⁄ 2 and a module containing the MuvB proteins Lin-37, Lin-52, Lin-5...
Ngày tải lên : 16/02/2014, 09:20
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Tài liệu Báo cáo khoa học: The pro-form of BMP-2 interferes with BMP-2 signalling by competing with BMP-2 for IA receptor binding pptx

Tài liệu Báo cáo khoa học: The pro-form of BMP-2 interferes with BMP-2 signalling by competing with BMP-2 for IA receptor binding pptx

... cells, refolded and purified [31]. The ECD was biotinylated and immobilized on streptavidin-coated BIAcore chips. Ligand binding was first analysed using the mature growth factor. The fast association rate and ... induction of alkaline phos- phatase in C2C12 cells. AP activity was measured by determination of the change in extinction (DE) per minute and microgram protein...
Ngày tải lên : 18/02/2014, 06:20
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Tài liệu Báo cáo khoa học: The chitinolytic system of Lactococcus lactis ssp. lactis comprises a nonprocessive chitinase and a chitin-binding protein that promotes the degradation of a- and b-chitin doc

Tài liệu Báo cáo khoa học: The chitinolytic system of Lactococcus lactis ssp. lactis comprises a nonprocessive chitinase and a chitin-binding protein that promotes the degradation of a- and b-chitin doc

... CBP21 and CHB1. Degradation of a- and b-chitin The degradation rates of a- and b-chitin were assayed with LlChi1 8A in the presence or absence of LlCBP3 3A. As both chitin variants, and especially a- chitin, ... chains); b-chitin (parallel packing of the chitin chains); and the minor polymorph c-chitin (mixture of parallel and antiparallel chain packing)...
Ngày tải lên : 18/02/2014, 08:20
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Tài liệu Báo cáo khoa học: The intracellular region of the Notch ligand Jagged-1 gains partial structure upon binding to synthetic membranes docx

Tài liệu Báo cáo khoa học: The intracellular region of the Notch ligand Jagged-1 gains partial structure upon binding to synthetic membranes docx

... ligands, apart from the identical PDZ binding motif (ATEV) found at the C-terminus of Delta-1 and Delta-4. The cytoplasmic tail of Jagged-1 (Fig. 1) contains a different C-terminal PDZ interacting ... A role of the cytoplasmic tail of membrane-spanning proteins in protein–protein interactions has also been proved, e.g. the case of the association between the...
Ngày tải lên : 18/02/2014, 16:20
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