... ribosome attains its high level of accuracy in translation, its catalytic triad (rRNA,ribosomal protein, and the peptidyl-tRNA substrate), and the mode of action of many antibiotics, enabling the design ... effort in preparing and analyzing the full-length protein can be extremelyrewarding, as shown by the information obtained with the tumor suppressor protein BRCA2 and its interac-tion with DNA [44,45]. ... structure of human growtharrest and DNA damage 45alpha (Gadd45alpha) and its interactions with proliferating cell nuclear antigen(PCNA) and Aurora A kinase. J Biol Chem 285,22196–22201.9 De Biasio...