Tài liệu Báo cáo khoa học: P25a ⁄ TPPP expression increases plasma membrane presentation of the dopamine transporter and enhances cellular sensitivity to dopamine toxicity pptx

Tài liệu Báo cáo khoa học: P25a ⁄ TPPP expression increases plasma membrane presentation of the dopamine transporter and enhances cellular sensitivity to dopamine toxicity pptx

Tài liệu Báo cáo khoa học: P25a ⁄ TPPP expression increases plasma membrane presentation of the dopamine transporter and enhances cellular sensitivity to dopamine toxicity pptx

... sensitized them to the toxicity of extracellular dopamine. Neuronal expression of p25a thus holds the potential to sensitize the cells toward dopamine and toxins carried by the dopamine transporter. Structured ... compilation ª 2010 FEBS 505 P25a ⁄ TPPP expression increases plasma membrane presentation of the dopamine transporter and...
Ngày tải lên : 14/02/2014, 21:20
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Tài liệu Báo cáo khoa học: Mixed lineage leukemia: a structure–function perspective of the MLL1 protein ppt

Tài liệu Báo cáo khoa học: Mixed lineage leukemia: a structure–function perspective of the MLL1 protein ppt

... from the Win motif of MLL1 bound to the WD40 repeat protein, WDR5 [24,25] and the C-terminal SET domain in the presence and absence of histone peptides and the cofactor product, S-adenosyl-homocysteine ... (green) bound to the central opening of WDR5 (PDB code 3EG6). The position of the conserved Arg 3765 is indicated. On the left, a stick representation is...
Ngày tải lên : 16/02/2014, 14:20
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Tài liệu Báo cáo khoa học: Neuronal growth-inhibitory factor (metallothionein-3): evaluation of the biological function of growth-inhibitory factor in the injured and neurodegenerative brain pdf

Tài liệu Báo cáo khoa học: Neuronal growth-inhibitory factor (metallothionein-3): evaluation of the biological function of growth-inhibitory factor in the injured and neurodegenerative brain pdf

... neurodegenerative disease. Synthesis and secretion of GIF in the brain Cellular and temporal localization of GIF synthesis Whilst the MT1 and MT2 isoforms are ubiquitously synthesized throughout most ... Cu(II) and Zn(II), only the Cu(II)- induced aggregation of Ab is toxic. The neurotoxicity of Cu(II)-induced Ab aggregation is related to the genera- tion of RO...
Ngày tải lên : 16/02/2014, 15:20
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Tài liệu Báo cáo khóa học: Quantitative analysis, using MALDI-TOF mass spectrometry, of the N-terminal hydrolysis and cyclization reactions of the activation 2 process of onconase pdf

Tài liệu Báo cáo khóa học: Quantitative analysis, using MALDI-TOF mass spectrometry, of the N-terminal hydrolysis and cyclization reactions of the activation 2 process of onconase pdf

... simplify the protocol and shorten the time needed to obtain a fully active ONC compared with other procedures described in the literature. The application of MALDI-TOF MS to the characterization of ... dehydration, together with acidification and dilution of the samples, stopped the reactions. This finding allowed the acquisition of spectra in the automatic mod...
Ngày tải lên : 19/02/2014, 12:20
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Tài liệu Báo cáo khoa học: Angiopoietin-like proteins: emerging targets for treatment of obesity and related metabolic diseases pptx

Tài liệu Báo cáo khoa học: Angiopoietin-like proteins: emerging targets for treatment of obesity and related metabolic diseases pptx

... we focus on the roles of ANGPTL2 and ANGPTL6 ⁄ AGF in obes- ity and related metabolic diseases, and discuss whether these ANGPTLs could be targets for the prevention and treatment of these conditions. Suppression ... ⁄ AGF null mice, and increases in the expression of PPARa, PPARd and PGC-1a in skeletal muscle of ANGPTL6 ⁄ AGF transgenic mice [14]. Mo...
Ngày tải lên : 14/02/2014, 22:20
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Tài liệu Báo cáo khoa học: Diol dehydratase-reactivating factor is a reactivase – evidence for multiple turnovers and subunit swapping with diol dehydratase pdf

Tài liệu Báo cáo khoa học: Diol dehydratase-reactivating factor is a reactivase – evidence for multiple turnovers and subunit swapping with diol dehydratase pdf

... incubated with the reactivase in the presence of ADP and Mg 2+ and followed by nondenaturing PAGE, the bands of the enzyme and the reactivase were markedly reduced in density, and two bands of the enzymeÆreactivase complexes ... Positions of DD and its subun- its (a D , b D and c D ) and the reactivase (DD-R) and its subunits (a R and b R ) are indicate...
Ngày tải lên : 15/02/2014, 01:20
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Tài liệu Báo cáo khoa học: Epidermal growth factor receptor in relation to tumor development: EGFR gene and cancer ppt

Tài liệu Báo cáo khoa học: Epidermal growth factor receptor in relation to tumor development: EGFR gene and cancer ppt

... the control of doxycyclin [22,23]. Expression of either EGFR mutant led to the develop- ment of adenocarcinomas similar to human BACs, and the withdrawal of doxycycline to reduce expression of the ... regula- tory domain. These provide docking sites for downstream molecules and lead to the evasion of apoptosis, to proliferation, to invasion and to...
Ngày tải lên : 16/02/2014, 09:20
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Tài liệu Báo cáo khoa học: Bacitracin is not a specific inhibitor of protein disulfide isomerase pptx

Tài liệu Báo cáo khoa học: Bacitracin is not a specific inhibitor of protein disulfide isomerase pptx

... BiP, PDI and DsbC. To further study the mechanism of action of bacitra- cin, the reduction of insulin was analyzed in the pres- ence of the PDI a domain and DsbA, which are capable of catalyzing the ... Triton X-100 and 2-propylphenol [3,38]. To study the effect of inhibitors of substrate binding on the reductive activity of PDI, the precipitation of...
Ngày tải lên : 16/02/2014, 14:20
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Tài liệu Báo cáo khoa học: Catabolite repression in Escherichia coli – a comparison of modelling approaches docx

Tài liệu Báo cáo khoa học: Catabolite repression in Escherichia coli – a comparison of modelling approaches docx

... synthesis; accelerator actuator: comprises the control and synthesis of the PTS mRNA; brake actua- tor: describes the control and synthesis of the PtsG repressor Mlc. Protein synthesis is described ... popular [21]. One advantage of the method of modular modeling is that the granularity of the submodels can easily be adjusted to the objective of the model...
Ngày tải lên : 18/02/2014, 13:20
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Tài liệu Báo cáo khoa học: DNA adenine methylation changes dramatically during establishment of symbiosis pdf

Tài liệu Báo cáo khoa học: DNA adenine methylation changes dramatically during establishment of symbiosis pdf

... obtained using NotI as the landmark enzyme and HinfI as the second dimension fragmentation enzyme. Although most of the spots are located on the top left (short in the first dimension and long in the second ... mixture [100 ng each of landmark- and HinfI-adapter and 5 lLof Ligation High solution (Toyobo, Tokyo, Japan) in 8.5 lL]. The mixture was incubated at 16 °C for...
Ngày tải lên : 19/02/2014, 02:20
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