Tài liệu Báo cáo khoa học: Interaction between very-KIND Ras guanine exchange factor and microtubule-associated protein 2, and its role in dendrite growth – structure and function of the second kinase noncatalytic C-lobe domain docx
Tài liệu Báo cáo khoa học: Interaction between very-KIND Ras guanine exchange factor and microtubule-associated protein 2, and its role in dendrite growth – structure and function of the second kinase noncatalytic C-lobe domain docx
... 1661 Interaction between very-KIND Ras guanine exchange factor and microtubule-associated protein 2, and its role in dendrite growth – structure and function of the second kinase noncatalytic C-lobe ... S-transferase; HMW, high-molecular-weight; KIND, kinase noncatalytic C-lobe domain; KIND1, first kinase noncatalytic C-lobe domain; KIND2, second kinase noncatalytic C-lobe domain; MAP2, microtubule-associated ... February2011)doi:10.1111/j.1742-4658.2011.08085.x The kinase noncatalytic C-lobe domain (KIND) is a putative protein protein interaction module. Four KIND-containing proteins, Spir-2 (actin-nuclear factor) , PTPN13 (protein tyrosine phosphatase),...
- 11
- 658
- 0
Tài liệu Báo cáo khoa học: Competition between innate multidrug resistance and intracellular binding of rhodamine dyes pdf
... comparison of rhodamine uptake, in the presence and the absence of uncouplers, allows the estimation of the effect of intracellular binding on the MDR phenomenon. The data detailed obtained in the present ... nm. Inhibition of the NBD-Cl-sensitive efflux allowed the uptake of TMRM and its quenching within the cells. Right: the various cell linesindicated in the figure were incubated for 15 min with the ... included the K562 cell line and its Pgp over-expressing subline(K562 ⁄ ADR), the GLC4 cell line and its MRP1 over-expressing subline (GLC4 ⁄ ADR), the 2008 cell line and its sublines over-expressingMRP1,...
- 12
- 651
- 0
Tài liệu Báo cáo khoa học: Relationships between structure, function and stability for pyridoxal 5¢-phosphate-dependent starch phosphorylase from Corynebacterium callunaeas revealed by reversible cofactor dissociation studies doc
... timing of steps involved in dimer formation and a ppearance of thermostabilization byphosphate has been examined. The role of the cofactor5¢-phosphate group in the induction of stability and stabil-ization ... [17]. Enzyme–oxyanioninteractions occur a t a protein site different from the activesite, and thermostabilization is the result of a protein conformational change induced by the binding event.Residues ... formation of an a po-oligomer induced by the b inding of the nucleotide sugar. The presence of maltopentaose (5 mM) resulted in a moderate 1.5-foldincrease in the half-life of apo-CcStP.Effects of...
- 11
- 636
- 0
Tài liệu Báo cáo khoa học: Interactions between M proteins of Streptococcus pyogenes and glycosaminoglycans promote bacterial adhesion to host cells pdf
... IgGFc-binding to the S -domain, and albumin-binding to the C-repeats [31].Recombinantly expressed fragments rA–S and rS–C3 are indicated. (D) The M1 protein and the A–S and S–C3 fragments of M1 ... protein and protein H appear to be involved in the interaction as the binding of 125I-labelled DS was reduced to isogenicderivatives of the AP1 strain lacking either of these surfaceproteins (Fig. ... streptococciTo establish the role of M proteins for the GAG interaction we again first focused on the AP1 system. AP1 expressestwo members of the M protein family; protein M1 and protein H. There was a clearly...
- 9
- 512
- 0
Tài liệu Báo cáo khoa học: Interaction of the small heat shock protein with molecular mass 25 kDa (hsp25) with actin doc
... and its 3D mutant on the kinetics of actin polymerization.Samples containing 1–4 lM of actin (10% of pyrene-labeled protein) were incubated for 5 min in the absence (1) or in the presence of ... The quantity of actin in the pellet was plotted against the totalquantity of actin in the sample.ResultsHeat denaturation of actinBefore starting the investigation of the HSP25–actin inter-action ... analyzed the effect of HSP25 on the polymerization of intact actin and aggregation of heated actin. Interaction of HSP25 with intact actin In the first series of experiments we analyzed the effect of HSP25...
- 10
- 431
- 0
Tài liệu Báo cáo khoa học: P25a ⁄ TPPP expression increases plasma membrane presentation of the dopamine transporter and enhances cellular sensitivity to dopamine toxicity pptx
... yielding the supernatant LS2, containing the cytosol-enriched fraction, and the pellet LP2, which isenriched in synaptic vesicles. The protein concentrationswere measured using the bicinchoninic ... sample buffer, and incubated for 30 minat 37 °C. The dithioerythreitol reduces the disulfide bridge in the cross-linker between biotin and the target proteins, and thus allows their analysis ... cross-linker allows cleavage between biotin and the target by reducing the disulfide bridge. The biotinyla-ted proteins were captured by incubating with NeutraAvidin beads. The total and surface-bound...
- 13
- 596
- 0
Tài liệu Báo cáo khoa học: Nucleolin/C23 mediates the antiapoptotic effect of heat shock protein 70 during oxidative stress pptx
... 1C).Increased nucleolin/C23 protein levels in Hsp70-transfected cells in response toH2O2-induced apoptosisWe next examined the expression of nucleolin ⁄ C23 protein in these cells in response ... byforming large molecular complexes with other factors,such as casein kinase II, c-Myb, midkine, histone H1,nucleophosmin, p53 and protein phosphatase 1. Anumber of studies, including our own, indicate ... These results also indicate that the nucleolin ⁄ C23 gene has a functional role in the growth control of cardiomyocytes, and its regulation may beclosely associated with the susceptibility of...
- 11
- 614
- 0
Tài liệu Báo cáo khoa học: Proteolysis of Pseudomonas exotoxin A within hepatic endosomes by cathepsins B and D produces fragments displaying in vitro ADP-ribosylating and apoptotic effects doc
... proteasecathepsin D, as indicated by the following observa-tions: (a) the inhibitor profile of the endosomalETA-degrading activity was very similar to that of cathepsins B and D [30]; and (b) the ... Lipoprotein binding and endosomal itinerary of the low density lipoprotein receptor-related protein in rat liver. Proc Natl Acad Sci USA 86, 931 8–9 322.T. El Hage et al. Proteolysis of ETA in ... protein synthesis and programmed cell death [2,3 ]. ETA is secreted as a single polypeptide chaincomposed of three structural and functional domains: domain Ia (amino acids 1–2 52), which binds...
- 15
- 588
- 0
Tài liệu Báo cáo khoa học: Solution structure of hirsutellin A – new insights into the active site and interacting interfaces of ribotoxins docx
... loop 2 of ribotox-ins in protein functionality and protein protein and protein lipid interactions has been demonstrated[10,2 9–3 1]. Thus, the first segment of the long loop 2 in a-sarcin has ... of the various groups in determining the dependence of the activity on pH.Comparison with other structures: structuralproperties of HtA regions involved in protein protein or protein lipid interactions The ... functionality, protein protein and protein lipid interactions, are also discussed. The truncation and reduced charge of the N-terminal hairpin in HtA may be compensatedfor by the extension and new...
- 10
- 607
- 0
Tài liệu Báo cáo khoa học: Oocyte membrane localization of vitellogenin receptor coincides with queen flying age, and receptor silencing by RNAi disrupts egg formation in fire ant virgin queens ppt
... levelscontinued to increase in virgin queens up to 60 days of age [36]. It was of interest to determine whether recep-tor protein expression paralleled transcript abundance in these virgin queens. The ... via the VgR include: (a) functional VgR translationalmachinery, which may be negatively regulated by lowlevels of JH in virgin queens; and (b) the correct locali-zation of the VgR protein in the ... bio-genic amine) levels in the brain and this may upregulateJH [58]. By contrast, the traditional positive relation-ship between nutrition and insulin signaling is inverted in honey bee adults, and...
- 14
- 482
- 0
Từ khóa: tài liệu báo cáo nghiên cứu khoa họctài liệu về báo cáo khoa họcbáo cáo khoa học tài chính côngbáo cáo khoa học số loài quý hiếm tại vườn quốc gia ba bểtai lieu bao cao thuc tap khoa co khitai lieu bao cao thuc tap tai khoa duoc benh vienNghiên cứu sự biến đổi một số cytokin ở bệnh nhân xơ cứng bì hệ thốngNghiên cứu sự hình thành lớp bảo vệ và khả năng chống ăn mòn của thép bền thời tiết trong điều kiện khí hậu nhiệt đới việt namMột số giải pháp nâng cao chất lượng streaming thích ứng video trên nền giao thức HTTPNghiên cứu vật liệu biến hóa (metamaterials) hấp thụ sóng điện tử ở vùng tần số THzGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANPhát triển mạng lưới kinh doanh nước sạch tại công ty TNHH một thành viên kinh doanh nước sạch quảng ninhĐịnh tội danh từ thực tiễn huyện Cần Giuộc, tỉnh Long An (Luận văn thạc sĩ)Thơ nôm tứ tuyệt trào phúng hồ xuân hươngChuong 2 nhận dạng rui roTổ chức và hoạt động của Phòng Tư pháp từ thực tiễn tỉnh Phú Thọ (Luận văn thạc sĩ)BT Tieng anh 6 UNIT 2Tranh tụng tại phiên tòa hình sự sơ thẩm theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn xét xử của các Tòa án quân sự Quân khu (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtGiáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtTrách nhiệm của người sử dụng lao động đối với lao động nữ theo pháp luật lao động Việt Nam từ thực tiễn các khu công nghiệp tại thành phố Hồ Chí Minh (Luận văn thạc sĩ)Đổi mới quản lý tài chính trong hoạt động khoa học xã hội trường hợp viện hàn lâm khoa học xã hội việt namMÔN TRUYỀN THÔNG MARKETING TÍCH HỢP